BLASTX 2.2.6 [Apr-09-2003]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= QAZ3f05.yg.3.1
(1626 letters)
Database: nr
3,454,138 sequences; 1,185,965,366 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|ABA94007.1| alpha-mannosidase [Oryza sativa (japonica cu... 570 0.0
ref|NP_189306.1| alpha-mannosidase [Arabidopsis thaliana] >... 428 e-149
dbj|BAB11126.1| alpha-mannosidase [Arabidopsis thaliana] 431 e-144
ref|NP_851037.2| alpha-mannosidase [Arabidopsis thaliana] >... 431 e-144
ref|NP_201416.1| alpha-mannosidase [Arabidopsis thaliana] >... 375 e-121
ref|NP_001031878.1| alpha-mannosidase [Arabidopsis thaliana] 337 e-116
ref|NP_919780.1| putative alpha-mannosidase [Oryza sativa (... 309 5e-89
gb|EAL40240.1| ENSANGP00000013227 [Anopheles gambiae str. P... 206 1e-65
ref|NP_776986.2| mannosidase, alpha, class 2B, member 1 [Bo... 206 1e-61
gb|AAC48763.1| lysosomal alpha-mannosidase [Bos taurus] 206 1e-61
emb|CAG12505.1| unnamed protein product [Tetraodon nigrovir... 197 4e-61
ref|XP_542048.2| PREDICTED: similar to Lysosomal alpha-mann... 205 5e-61
ref|XP_867548.1| PREDICTED: similar to Lysosomal alpha-mann... 205 5e-61
emb|CAH91346.1| hypothetical protein [Pongo pygmaeus] 202 9e-61
gb|EAA44350.2| ENSANGP00000023272 [Anopheles gambiae str. P... 189 1e-60
gb|AAH00736.1| Mannosidase, alpha, class 2B, member 1 [Homo... 201 2e-60
gb|AAC34130.1| lysosomal alpha-mannosidase [Homo sapiens] 201 2e-60
gb|AAC51362.1| lysosomal alpha-mannosidase [Homo sapiens] >... 201 2e-60
dbj|BAD93158.1| mannosidase, alpha, class 2B, member 1 prec... 201 2e-60
gb|AAC50812.1| lysosomal acid alpha-mannosidase [Homo sapiens] 201 2e-60
gb|AAB03816.1| alpha-mannosidase 201 2e-60
ref|XP_795985.1| PREDICTED: similar to Lysosomal alpha-mann... 203 6e-60
gb|AAL58982.1| lysosomal alpha-mannosidase [Cavia porcellus... 205 8e-60
gb|AAL58984.1| lysosomal alpha-mannosidase [Cavia porcellus] 205 8e-60
gb|AAL58983.1| lysosomal alpha-mannosidase [Cavia porcellus] 205 8e-60
ref|NP_001009222.1| mannosidase, alpha, class 2B, member 1 ... 198 5e-59
dbj|BAD51966.1| mannosidase, alpha, class 2B, member 1 [Mac... 196 6e-59
ref|XP_624628.1| PREDICTED: similar to ENSANGP00000013227 [... 194 4e-58
ref|NP_001014354.1| hypothetical protein LOC541519 [Danio r... 203 2e-57
ref|NP_955436.1| mannosidase 2, alpha B1 [Rattus norvegicus... 188 1e-56
gb|AAH05430.1| Mannosidase 2, alpha B1 [Mus musculus] >gi|1... 191 4e-56
dbj|BAE28235.1| unnamed protein product [Mus musculus] >gi|... 191 4e-56
dbj|BAE42288.1| unnamed protein product [Mus musculus] 191 4e-56
gb|AAC78560.1| lysosomal alpha-mannosidase [Mus musculus] >... 191 4e-56
gb|AAC09470.1| lysosomal alpha-mannosidase [Mus musculus] 191 4e-56
gb|AAC53369.1| alpha-D-mannosidase 191 4e-56
ref|NP_723591.1| CG6206-PB, isoform B [Drosophila melanogas... 176 7e-54
ref|NP_609408.1| CG6206-PA, isoform A [Drosophila melanogas... 176 7e-54
pir||JC2200 alpha-mannosidase (EC 3.2.1.24) precursor - human 179 1e-53
dbj|BAD93831.1| alpha-mannosidase [Arabidopsis thaliana] 211 5e-53
gb|EAL32868.1| GA21810-PA [Drosophila pseudoobscura] 179 1e-50
gb|ABC86349.1| IP13633p [Drosophila melanogaster] 165 1e-48
ref|NP_609407.1| CG5322-PA [Drosophila melanogaster] >gi|72... 165 1e-48
ref|XP_629747.1| alpha-mannosidase [Dictyostelium discoideu... 181 6e-48
pdb|1O7D|D Chain D, The Structure Of The Bovine Lysosomal A... 160 8e-47
ref|NP_609251.1| CG9465-PA [Drosophila melanogaster] >gi|72... 171 1e-46
ref|XP_512408.1| PREDICTED: similar to Mannosidase, alpha, ... 157 2e-44
sp|P34098|MANA_DICDI Lysosomal alpha-mannosidase precursor ... 169 3e-44
ref|NP_609252.1| CG9466-PA [Drosophila melanogaster] >gi|16... 181 1e-43
ref|XP_701739.1| PREDICTED: hypothetical protein XP_696647 ... 157 2e-43
ref|NP_609250.2| CG9463-PA [Drosophila melanogaster] >gi|22... 165 2e-43
gb|AAL48871.2| RE28991p [Drosophila melanogaster] 162 1e-42
emb|CAE68642.1| Hypothetical protein CBG14532 [Caenorhabdit... 129 2e-41
gb|AAM50967.1| RE08556p [Drosophila melanogaster] 166 3e-39
gb|EAS02484.1| Glycosyl hydrolases family 38 protein [Tetra... 153 3e-39
ref|NP_609253.1| CG9468-PA [Drosophila melanogaster] >gi|22... 164 1e-38
gb|EAS02485.1| Glycosyl hydrolases family 38 protein [Tetra... 145 2e-36
gb|EAR94085.1| Glycosyl hydrolases family 38 protein [Tetra... 149 3e-34
ref|XP_812205.1| lysosomal alpha-mannosidase precursor [Try... 134 2e-33
ref|XP_819105.1| lysosomal alpha-mannosidase precursor [Try... 134 6e-33
gb|EAS02491.1| Glycosyl hydrolases family 38 protein [Tetra... 129 1e-31
gb|EAS02490.1| Glycosyl hydrolases family 38 protein [Tetra... 126 1e-30
ref|XP_822510.1| lysosomal alpha-mannosidase precursor [Try... 129 2e-30
gb|EAR94069.1| Glycosyl hydrolases family 38 protein [Tetra... 129 4e-28
gb|EAS04708.1| Glycosyl hydrolases family 38 protein [Tetra... 128 6e-28
gb|AAA81731.2| Hypothetical protein F55D10.1 [Caenorhabditi... 121 7e-26
gb|AAX26929.2| SJCHGC06403 protein [Schistosoma japonicum] 110 2e-22
gb|AAC72969.1| lysosomal alpha mannosidase [Trypanosoma cruzi] 100 2e-19
ref|XP_420805.1| PREDICTED: similar to hypothetical protein... 97 2e-18
gb|EAA13579.3| ENSANGP00000014255 [Anopheles gambiae str. P... 74 7e-15
ref|NP_524291.2| Mannosidase II CG18802-PA [Drosophila mela... 72 2e-14
emb|CAA54732.1| putative golgi alpha-mannosidase II [Drosop... 72 2e-14
emb|CAA10755.1| alpha-mannosidase II [Drosophila melanogaster] 72 2e-14
pdb|1R34|A Chain A, Golgi Alpha-Mannosidase Ii Complex With... 72 2e-14
pdb|1QX1|A Chain A, Golgi Alpha-Mannosidase Ii D341n Mutant... 72 2e-14
pdb|1PS3|A Chain A, Golgi Alpha-Mannosidase Ii In Complex W... 72 2e-14
pdb|1HWW|A Chain A, Golgi Alpha-Mannosidase Ii In Complex W... 72 2e-14
ref|NP_032576.1| mannosidase alpha class 2B member 2 [Mus m... 83 4e-14
dbj|BAE38153.1| unnamed protein product [Mus musculus] 83 4e-14
dbj|BAC30580.1| unnamed protein product [Mus musculus] >gi|... 83 4e-14
dbj|BAB23655.1| unnamed protein product [Mus musculus] 83 4e-14
ref|XP_610717.2| PREDICTED: similar to Epididymis-specific ... 82 7e-14
gb|AAH94773.1| Mannosidase, alpha, class 2B, member 2 [Homo... 81 1e-13
ref|NP_056089.1| mannosidase, alpha, class 2B, member 2 [Ho... 81 1e-13
gb|AAH33307.1| Mannosidase, alpha, class 2B, member 2 [Homo... 81 1e-13
emb|CAD89971.1| hypothetical protein [Homo sapiens] 81 1e-13
emb|CAH90164.1| hypothetical protein [Pongo pygmaeus] >gi|6... 81 1e-13
sp|Q9Y2E5|MA2B2_HUMAN Epididymis-specific alpha-mannosidase... 81 1e-13
pdb|1HTY|A Chain A, Golgi Alpha-Mannosidase Ii 70 1e-13
gb|EAL26975.1| GA15085-PA [Drosophila pseudoobscura] 72 2e-13
sp|Q28949|MA2B2_PIG Epididymis-specific alpha-mannosidase p... 78 9e-13
ref|NP_999014.1| 135kDa alpha-D-mannosidase [Sus scrofa] >g... 78 9e-13
emb|CAG03449.1| unnamed protein product [Tetraodon nigrovir... 70 2e-12
ref|NP_006113.2| mannosidase, alpha, class 2A, member 2 [Ho... 70 4e-12
gb|AAH72937.1| MGC80473 protein [Xenopus laevis] 71 4e-12
emb|CAE75350.1| Hypothetical protein CBG23330 [Caenorhabdit... 71 4e-12
dbj|BAA92325.1| geraniol-responsible factor 15 [Matricaria ... 76 5e-12
emb|CAJ55257.1| Hypothetical protein F58H1.1b [Caenorhabdit... 70 1e-11
ref|NP_505995.1| F58H1.1 [Caenorhabditis elegans] >gi|38778... 70 1e-11
ref|XP_689538.1| PREDICTED: similar to mannosidase, alpha, ... 68 1e-11
ref|XP_624759.1| PREDICTED: similar to CG18802-PA [Apis mel... 72 5e-11
ref|XP_605840.2| PREDICTED: similar to mannosidase, alpha, ... 65 1e-10
ref|XP_877989.1| PREDICTED: similar to mannosidase, alpha, ... 65 1e-10
ref|XP_642278.1| hypothetical protein DDB0218084 [Dictyoste... 70 2e-10
dbj|BAD32345.1| mKIAA0935 protein [Mus musculus] 70 2e-10
ref|XP_642277.1| hypothetical protein DDB0218083 [Dictyoste... 70 2e-10
emb|CAG04580.1| unnamed protein product [Tetraodon nigrovir... 70 2e-10
dbj|BAA76779.2| KIAA0935 protein [Homo sapiens] 70 2e-10
ref|XP_218816.3| PREDICTED: similar to mannosidase, alpha, ... 67 2e-09
dbj|BAE23268.1| unnamed protein product [Mus musculus] 67 2e-09
gb|AAH55006.1| Man2a2 protein [Mus musculus] 67 2e-09
ref|XP_545863.2| PREDICTED: similar to mannosidase, alpha, ... 66 5e-09
ref|XP_599803.2| PREDICTED: similar to mannosidase, alpha, ... 65 6e-09
ref|XP_545995.2| PREDICTED: similar to mannosidase, alpha, ... 65 8e-09
ref|XP_396290.2| PREDICTED: similar to ENSANGP00000010944 [... 64 1e-08
ref|XP_852836.1| PREDICTED: similar to Epididymis-specific ... 64 1e-08
ref|XP_517864.1| PREDICTED: similar to mannosidase, alpha, ... 63 2e-08
ref|NP_002363.2| mannosidase, alpha, class 2A, member 1 [Ho... 63 2e-08
gb|AAC50302.1| alpha mannosidase II >gi|3122380|sp|Q16706|M... 63 2e-08
dbj|BAA10017.1| golgi alpha-mannosidaseII [Homo sapiens] 63 2e-08
ref|XP_545897.2| PREDICTED: similar to Epididymis-specific ... 64 2e-08
dbj|BAC92711.1| alpha-mannosidase [Drosophila melanogaster] 63 4e-08
gb|EAA05368.2| ENSANGP00000010944 [Anopheles gambiae str. P... 63 4e-08
ref|XP_601803.2| PREDICTED: similar to Epididymis-specific ... 63 4e-08
ref|XP_413979.1| PREDICTED: similar to Alpha-mannosidase II... 57 5e-08
ref|NP_650494.2| -Man-IIb CG4606-PA [Drosophila melanogaste... 62 5e-08
dbj|BAA75817.1| alpha-mannosidase [Drosophila melanogaster] 62 5e-08
dbj|BAA09510.1| alpha mannosidase II isozyme [Homo sapiens]... 61 1e-07
ref|XP_642245.1| hypothetical protein DDB0205324 [Dictyoste... 61 2e-07
emb|CAA43480.1| mannosyl-oligosaccharide 1,3-1,6-alpha-mann... 60 3e-07
gb|AAR15492.1| glycosyl hydrolase [Arabidopsis arenosa] 59 5e-07
dbj|BAD45807.1| putative glycosyl hydrolase [Oryza sativa (... 59 5e-07
emb|CAF89893.1| unnamed protein product [Tetraodon nigrovir... 59 6e-07
emb|CAF87950.1| unnamed protein product [Tetraodon nigrovir... 59 6e-07
emb|CAF87266.1| unnamed protein product [Tetraodon nigrovir... 59 6e-07
pdb|1O7D|E Chain E, The Structure Of The Bovine Lysosomal A... 59 8e-07
ref|NP_196999.1| alpha-mannosidase [Arabidopsis thaliana] >... 59 8e-07
ref|XP_799148.1| PREDICTED: similar to mannosidase, alpha, ... 58 1e-06
ref|XP_646960.1| hypothetical protein DDB0202336 [Dictyoste... 58 1e-06
gb|EAL28526.1| GA18295-PA [Drosophila pseudoobscura] 57 2e-06
gb|AAB62719.1| alpha-mannosidase II [Spodoptera frugiperda] 55 1e-05
gb|EAL40242.1| ENSANGP00000028437 [Anopheles gambiae str. P... 55 1e-05
ref|XP_606944.2| PREDICTED: similar to Epididymis-specific ... 55 1e-05
gb|EAS02486.1| conserved hypothetical protein [Tetrahymena ... 54 1e-05
ref|XP_517094.1| PREDICTED: similar to Mannosidase, alpha, ... 53 4e-05
pir||JC4037 alpha-mannosidase II, Golgi - fruit fly (Drosop... 40 5e-05
dbj|BAE42419.1| unnamed protein product [Mus musculus] >gi|... 52 6e-05
emb|CAE66941.1| Hypothetical protein CBG12333 [Caenorhabdit... 52 6e-05
gb|AAL38616.1| AT5g14950/F2G14_70 [Arabidopsis thaliana] >g... 52 9e-05
ref|XP_688638.1| PREDICTED: similar to mannosidase, alpha, ... 44 2e-04
gb|AAB52345.2| Hypothetical protein F48C1.1 [Caenorhabditis... 50 3e-04
dbj|BAD94717.1| alpha-mannosidase [Arabidopsis thaliana] 50 4e-04
ref|XP_852823.1| PREDICTED: similar to mannosidase, alpha, ... 49 8e-04
gb|AAP92617.1| Ab2-450 [Rattus norvegicus] 47 0.002
ref|XP_637323.1| hypothetical protein DDB0187376 [Dictyoste... 46 0.004
ref|XP_688626.1| PREDICTED: similar to Alpha-mannosidase II... 45 0.007
ref|XP_875484.1| PREDICTED: similar to Epididymis-specific ... 41 0.17
gb|AAW27826.1| SJCHGC06726 protein [Schistosoma japonicum] 40 0.29
ref|YP_437108.1| Polyketide synthase modules and related pr... 39 0.49
ref|XP_653893.1| hypothetical protein 69.t00014 [Entamoeba ... 39 0.64
gb|AAL11728.1| membrane protein NBR1 [Mus musculus] 39 0.64
ref|XP_716055.1| hypothetical protein CaO19_2215 [Candida a... 38 1.4
dbj|BAA14368.1| surface protein antigen precursor [Streptoc... 37 1.9
dbj|BAD91216.1| antigen I/II [Streptococcus downei] 37 1.9
ref|NP_504860.1| F07G11.1 [Caenorhabditis elegans] >gi|1086... 37 1.9
emb|CAD16742.1| PROBABLE DNA-DIRECTED RNA POLYMERASE (BETA'... 37 2.4
ref|ZP_00946351.1| DNA-directed RNA polymerase beta chain [... 37 2.4
gb|AAB41815.1| proline rich protein [Medicago sativa] 37 3.2
ref|NP_954610.1| taste receptor, type 2, member 135 [Mus mu... 36 5.4
gb|AAR29905.1| putative response regulator receiver RIM15p ... 36 5.4
tpg|DAA01236.1| TPA: TPA_exp: candidate taste receptor mt2r... 36 5.4
ref|ZP_00461715.1| extracellular solute-binding protein, fa... 36 5.4
ref|ZP_00569278.1| Amidohydrolase 2 [Frankia sp. EAN1pec] >... 36 5.4
gb|AAA26977.1| antigen I 35 7.0
ref|XP_537305.2| PREDICTED: similar to Rho-associated prote... 35 7.0
ref|XP_628930.1| hypothetical protein DDB0219906 [Dictyoste... 35 7.0
emb|CAA40973.1| antigen I /II [Streptococcus sobrinus] >gi|... 35 7.0
gb|EAQ84058.1| hypothetical protein CHGG_10462 [Chaetomium ... 35 9.2
>gb|ABA94007.1| alpha-mannosidase [Oryza sativa (japonica cultivar-group)]
Length = 1020
Score = 570 bits (1468), Expect(2) = 0.0
Identities = 272/319 (85%), Positives = 299/319 (93%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VYK KD++ETEFIVGPIPVDDGNGKE++TE+VTNM TNKTFYTDSSGRDFIKRIRDYRSE
Sbjct: 700 VYKGKDYVETEFIVGPIPVDDGNGKELSTEVVTNMATNKTFYTDSSGRDFIKRIRDYRSE 759
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WKIEVHQPIAGNYYPVNLGIYVEDGS+ELS+LVDRS+GG+SIKDGQIELMLHRRLLHDDG
Sbjct: 760 WKIEVHQPIAGNYYPVNLGIYVEDGSRELSILVDRSVGGASIKDGQIELMLHRRLLHDDG 819
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GVAEALNET C D QCEGL+IQGKYY+KIDPQGEGARWRRTFGQEIYSPLL+AF EQDG
Sbjct: 820 RGVAEALNETTCFDNQCEGLVIQGKYYLKIDPQGEGARWRRTFGQEIYSPLLIAFAEQDG 879
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
GNW NSHV KFSAMD YSLPDNVA+LTLQELEDG+VLLR AHLYEAGE KDLS+LAS+D
Sbjct: 880 GNWVNSHVTKFSAMDPAYSLPDNVALLTLQELEDGTVLLRLAHLYEAGEHKDLSALASVD 939
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLVVEL 1277
LKRVFP+KKI K++ETSLSANQER+AMEKKRLKWK +G ADEK+VRGGPVDPSKLVV+L
Sbjct: 940 LKRVFPDKKIVKIVETSLSANQERSAMEKKRLKWKVEGPPADEKIVRGGPVDPSKLVVDL 999
Query: 1278 GPMEIRTFIVSFDHISDKQ 1334
GPMEIRTF+++F S KQ
Sbjct: 1000 GPMEIRTFLINFAPQSGKQ 1018
Score = 202 bits (513), Expect(2) = 0.0
Identities = 99/124 (79%), Positives = 108/124 (87%)
Frame = +2
Query: 20 KKSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKY 199
KKSA +S ST +S QGSE+SN+Q+GQG LKLQYN AG LSLYS+SKT V+ANFEQKYKY
Sbjct: 581 KKSASVSLMSTLHSSQGSENSNMQIGQGQLKLQYNAAGALSLYSNSKTQVEANFEQKYKY 640
Query: 200 YIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
YIGQDGNGSDPQASGAYIFRPNGTVPI TDGQV LTVLRG ILDEVHQQIN WIYQI R
Sbjct: 641 YIGQDGNGSDPQASGAYIFRPNGTVPIKTDGQVPLTVLRGSILDEVHQQINPWIYQINRV 700
Query: 380 LQGE 391
+G+
Sbjct: 701 YKGK 704
>ref|NP_189306.1| alpha-mannosidase [Arabidopsis thaliana]
emb|CAA72432.1| alpha-mannosidase precursor [Arabidopsis thaliana]
emb|CAA66821.1| alpha-mannosidase [Arabidopsis thaliana]
gb|AAM47314.1| AT3g26720/MLJ15_12 [Arabidopsis thaliana]
gb|AAK62592.1| AT3g26720/MLJ15_12 [Arabidopsis thaliana]
dbj|BAB01735.1| alpha-mannosidase [Arabidopsis thaliana]
Length = 1019
Score = 428 bits (1100), Expect(2) = e-149
Identities = 207/324 (63%), Positives = 260/324 (80%), Gaps = 4/324 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VYK K+ E EF +GPIP DDG KE+ T++ T M TN TFYTDS+GRDFIKRIRD+R++
Sbjct: 693 VYKGKNHAEIEFTIGPIPADDGISKEIITKLTTTMKTNGTFYTDSNGRDFIKRIRDFRTD 752
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W ++V+QP+AGNYYP+NLGIY++D + ELSVLVDR++GGSS+++GQIELMLHRR+ HDD
Sbjct: 753 WDLQVYQPVAGNYYPLNLGIYMQDKTSELSVLVDRAVGGSSLENGQIELMLHRRMQHDDI 812
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GV E LNETVCL + C+GL IQGK+YV+ID G+GA+WRRTFGQEIYSPLL+AFTEQ+G
Sbjct: 813 RGVGEILNETVCLPEGCKGLTIQGKFYVQIDKPGDGAKWRRTFGQEIYSPLLIAFTEQEG 872
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
+W NSH FSA + +YSLP NVA+LTLQELE+G VLLR AHL+E GED + S +A ++
Sbjct: 873 DSWINSHKTTFSAFEPSYSLPKNVALLTLQELENGEVLLRLAHLFEVGEDSEYSVMAKVE 932
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLVVEL 1277
LK++F KKI +V ETSLS NQE+A MEK+RL WK +GSA +E V RG VD KLVVEL
Sbjct: 933 LKKLFHNKKIREVKETSLSGNQEKAEMEKRRLIWKVEGSAGEE-VKRGEAVDAEKLVVEL 991
Query: 1278 GPMEIRTFIVSFDH----ISDKQQ 1337
PMEIRT ++ FD + DK+Q
Sbjct: 992 VPMEIRTLLIKFDDQIEMVGDKEQ 1015
Score = 125 bits (315), Expect(2) = e-149
Identities = 60/116 (51%), Positives = 83/116 (71%), Gaps = 1/116 (0%)
Frame = +2
Query: 47 STQYSPQGSESSNLQVGQGNLKLQYNEAG-KLSLYSDSKTMVQANFEQKYKYYIGQDGNG 223
S Y GS + N++VGQGNLKL+Y+E G K++ + +K V A EQ Y YYIG +G
Sbjct: 584 SASYVTSGSMNQNVEVGQGNLKLRYSEEGVKITRHLSTKNQVTA--EQSYAYYIGSNGTD 641
Query: 224 SDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
DPQASGAY+FRP+G +PI + + LT+++GP+ DEVHQ++NSWI QITR +G+
Sbjct: 642 KDPQASGAYVFRPDGVLPIKSKEEAQLTIVQGPLFDEVHQELNSWISQITRVYKGK 697
>dbj|BAB11126.1| alpha-mannosidase [Arabidopsis thaliana]
Length = 1030
Score = 431 bits (1109), Expect(2) = e-144
Identities = 209/316 (66%), Positives = 257/316 (81%), Gaps = 3/316 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VYK K+ +E EFIVG IP+DDG GKEV T+I +++ +NKTFYTDSSGRD+IKRIRDYRS+
Sbjct: 702 VYKGKEHVEVEFIVGNIPIDDGIGKEVVTQISSSLKSNKTFYTDSSGRDYIKRIRDYRSD 761
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK++V+QPIAGNYYP+N GIY++D KE SV+VDR+ GGSSI DGQ+ELMLHRRLL DD
Sbjct: 762 WKLDVNQPIAGNYYPINHGIYLQDSKKEFSVMVDRAFGGSSIVDGQVELMLHRRLLLDDS 821
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GVAE LNETVC+ +C GL IQGKYY +IDP GEGA+WRRTFGQEIYSPLLLAF +QD
Sbjct: 822 RGVAENLNETVCVQDKCTGLTIQGKYYYRIDPYGEGAKWRRTFGQEIYSPLLLAFAQQDD 881
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
G + A FS +D +YSLPDNVA+LTLQEL+DG+VLLR AHLYE EDK+LS +AS++
Sbjct: 882 GKPMSFGAASFSGIDPSYSLPDNVALLTLQELDDGNVLLRLAHLYEVEEDKELSGVASVE 941
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAA---DEKVVRGGPVDPSKLV 1268
LK++FP KKIGK+ E SLSANQER+ MEKKRL WK +G + ++K RG +DP KL
Sbjct: 942 LKKLFPGKKIGKLTEMSLSANQERSTMEKKRLVWKVEGEGSYGEEKKAKRGREIDPRKLE 1001
Query: 1269 VELGPMEIRTFIVSFD 1316
+EL PMEIRT ++ +
Sbjct: 1002 MELYPMEIRTVLIHLE 1017
Score = 105 bits (263), Expect(2) = e-144
Identities = 57/129 (44%), Positives = 80/129 (62%), Gaps = 5/129 (3%)
Frame = +2
Query: 20 KKSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYK 196
KK+ SSKS + E S + +G G+LKL ++ + G Y + +T + +Q +
Sbjct: 578 KKTDGYSSKSYVSNILKGEQSIINIGHGHLKLSFSTDQGTAINYVNGRTSMTEPVKQTFS 637
Query: 197 YYIGQDGNGSD----PQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
YY +G+ PQ SGAY+FRPNGT PI+ +GQV LTV+ GP++DEVHQQIN WI
Sbjct: 638 YYSAYNGSNDKEPLIPQNSGAYVFRPNGTFPINPEGQVPLTVIHGPLVDEVHQQINPWIS 697
Query: 365 QITRRLQGE 391
QITR +G+
Sbjct: 698 QITRVYKGK 706
>ref|NP_851037.2| alpha-mannosidase [Arabidopsis thaliana]
ref|NP_196902.2| alpha-mannosidase [Arabidopsis thaliana]
gb|AAN15620.1| alpha-mannosidase [Arabidopsis thaliana]
gb|AAM20555.1| alpha-mannosidase [Arabidopsis thaliana]
Length = 1024
Score = 431 bits (1109), Expect(2) = e-144
Identities = 209/316 (66%), Positives = 257/316 (81%), Gaps = 3/316 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VYK K+ +E EFIVG IP+DDG GKEV T+I +++ +NKTFYTDSSGRD+IKRIRDYRS+
Sbjct: 696 VYKGKEHVEVEFIVGNIPIDDGIGKEVVTQISSSLKSNKTFYTDSSGRDYIKRIRDYRSD 755
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK++V+QPIAGNYYP+N GIY++D KE SV+VDR+ GGSSI DGQ+ELMLHRRLL DD
Sbjct: 756 WKLDVNQPIAGNYYPINHGIYLQDSKKEFSVMVDRAFGGSSIVDGQVELMLHRRLLLDDS 815
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GVAE LNETVC+ +C GL IQGKYY +IDP GEGA+WRRTFGQEIYSPLLLAF +QD
Sbjct: 816 RGVAENLNETVCVQDKCTGLTIQGKYYYRIDPYGEGAKWRRTFGQEIYSPLLLAFAQQDD 875
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
G + A FS +D +YSLPDNVA+LTLQEL+DG+VLLR AHLYE EDK+LS +AS++
Sbjct: 876 GKPMSFGAASFSGIDPSYSLPDNVALLTLQELDDGNVLLRLAHLYEVEEDKELSGVASVE 935
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAA---DEKVVRGGPVDPSKLV 1268
LK++FP KKIGK+ E SLSANQER+ MEKKRL WK +G + ++K RG +DP KL
Sbjct: 936 LKKLFPGKKIGKLTEMSLSANQERSTMEKKRLVWKVEGEGSYGEEKKAKRGREIDPRKLE 995
Query: 1269 VELGPMEIRTFIVSFD 1316
+EL PMEIRT ++ +
Sbjct: 996 MELYPMEIRTVLIHLE 1011
Score = 105 bits (263), Expect(2) = e-144
Identities = 57/129 (44%), Positives = 80/129 (62%), Gaps = 5/129 (3%)
Frame = +2
Query: 20 KKSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYK 196
KK+ SSKS + E S + +G G+LKL ++ + G Y + +T + +Q +
Sbjct: 572 KKTDGYSSKSYVSNILKGEQSIINIGHGHLKLSFSTDQGTAINYVNGRTSMTEPVKQTFS 631
Query: 197 YYIGQDGNGSD----PQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
YY +G+ PQ SGAY+FRPNGT PI+ +GQV LTV+ GP++DEVHQQIN WI
Sbjct: 632 YYSAYNGSNDKEPLIPQNSGAYVFRPNGTFPINPEGQVPLTVIHGPLVDEVHQQINPWIS 691
Query: 365 QITRRLQGE 391
QITR +G+
Sbjct: 692 QITRVYKGK 700
>ref|NP_201416.1| alpha-mannosidase [Arabidopsis thaliana]
dbj|BAB10420.1| alpha-mannosidase [Arabidopsis thaliana]
Length = 1047
Score = 375 bits (964), Expect(2) = e-121
Identities = 186/315 (59%), Positives = 238/315 (75%), Gaps = 3/315 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGN--GKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYR 551
+YKEK+ E EF +GPI V G+ GKE+ T +VT+M T K FYTDS+GRDF+KR+RD R
Sbjct: 722 LYKEKEHAEFEFTIGPISVGKGHLTGKEIITRMVTDMTTAKEFYTDSNGRDFLKRVRDNR 781
Query: 552 SEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHD 731
++W +EV++PIAGNYYP+NLG+Y++D ELSVLVDR+ GG+SIKDG+IELMLHRR D
Sbjct: 782 TDWHLEVNEPIAGNYYPLNLGMYIKDEKAELSVLVDRATGGASIKDGEIELMLHRRTSMD 841
Query: 732 DGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQ 911
D +GV E+L ETVC++ C GL I+G YYV I+ GEG RWRR GQEIYSPLL+AF +
Sbjct: 842 DSRGVEESLVETVCVNDTCAGLTIRGNYYVSINKVGEGGRWRRETGQEIYSPLLMAFAHE 901
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLAS 1091
+ W S+ K AMD Y+LP N+A++TL+EL+ G+VLLR AHLYEAGED D S +A
Sbjct: 902 NKEKWKASNTVKGYAMDHLYTLPQNIALITLEELDLGNVLLRLAHLYEAGEDSDYSKIAK 961
Query: 1092 IDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAAD-EKVVRGGPVDPSKLV 1268
++LK++F K I +V E SLSANQE+ M K+++KWK +G A +RGGPVD S LV
Sbjct: 962 VELKKLFSGKMIKEVTEMSLSANQEKVKM-KEKMKWKVEGEAEQPSSPLRGGPVDKSTLV 1020
Query: 1269 VELGPMEIRTFIVSF 1313
VELGPMEIRTF+V F
Sbjct: 1021 VELGPMEIRTFVVQF 1035
Score = 84.3 bits (207), Expect(2) = e-121
Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 17/141 (12%)
Frame = +2
Query: 5 ASANLKKSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANF 181
+ A+ + S + S SP + + ++G GNLK+ ++ ++G+L +S+T
Sbjct: 584 SKASAQGSNNHKHSSVMLSPMNNTT---EIGPGNLKMVFSSDSGRLERMYNSRTGADIKV 640
Query: 182 EQKYKYYIGQDGNGSDPQASGAYIFRPNGTV--PIST--------------DGQVSLTVL 313
+Q Y +Y G+ DPQ SGAYIFRPNG++ P+S+ + Q L ++
Sbjct: 641 DQNYFWYASNVGDAKDPQVSGAYIFRPNGSLAYPVSSSKICTVTSAFIGNGNVQSKLQIV 700
Query: 314 RGPILDEVHQQINSWIYQITR 376
RGP++DEVHQQ + W+ Q+ R
Sbjct: 701 RGPLIDEVHQQFSPWVAQVVR 721
>ref|NP_001031878.1| alpha-mannosidase [Arabidopsis thaliana]
Length = 921
Score = 337 bits (864), Expect(2) = e-116
Identities = 160/226 (70%), Positives = 191/226 (84%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VYK K+ +E EFIVG IP+DDG GKEV T+I +++ +NKTFYTDSSGRD+IKRIRDYRS+
Sbjct: 696 VYKGKEHVEVEFIVGNIPIDDGIGKEVVTQISSSLKSNKTFYTDSSGRDYIKRIRDYRSD 755
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK++V+QPIAGNYYP+N GIY++D KE SV+VDR+ GGSSI DGQ+ELMLHRRLL DD
Sbjct: 756 WKLDVNQPIAGNYYPINHGIYLQDSKKEFSVMVDRAFGGSSIVDGQVELMLHRRLLLDDS 815
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GVAE LNETVC+ +C GL IQGKYY +IDP GEGA+WRRTFGQEIYSPLLLAF +QD
Sbjct: 816 RGVAENLNETVCVQDKCTGLTIQGKYYYRIDPYGEGAKWRRTFGQEIYSPLLLAFAQQDD 875
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYE 1055
G + A FS +D +YSLPDNVA+LTLQEL+DG+VLLR AHLYE
Sbjct: 876 GKPMSFGAASFSGIDPSYSLPDNVALLTLQELDDGNVLLRLAHLYE 921
Score = 105 bits (263), Expect(2) = e-116
Identities = 57/129 (44%), Positives = 80/129 (62%), Gaps = 5/129 (3%)
Frame = +2
Query: 20 KKSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYK 196
KK+ SSKS + E S + +G G+LKL ++ + G Y + +T + +Q +
Sbjct: 572 KKTDGYSSKSYVSNILKGEQSIINIGHGHLKLSFSTDQGTAINYVNGRTSMTEPVKQTFS 631
Query: 197 YYIGQDGNGSD----PQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
YY +G+ PQ SGAY+FRPNGT PI+ +GQV LTV+ GP++DEVHQQIN WI
Sbjct: 632 YYSAYNGSNDKEPLIPQNSGAYVFRPNGTFPINPEGQVPLTVIHGPLVDEVHQQINPWIS 691
Query: 365 QITRRLQGE 391
QITR +G+
Sbjct: 692 QITRVYKGK 700
>ref|NP_919780.1| putative alpha-mannosidase [Oryza sativa (japonica cultivar-group)]
gb|AAM08419.1| Putative alpha-mannosidase [Oryza sativa]
gb|AAL73069.1| Putative alpha-mannosidase [Oryza sativa]
gb|AAP52067.1| Putative alpha-mannosidase [Oryza sativa (japonica cultivar-group)]
Length = 438
Score = 309 bits (792), Expect(2) = 5e-89
Identities = 156/315 (49%), Positives = 213/315 (67%), Gaps = 3/315 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGN--GKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYR 551
+YK K+ E E+ +GPIPVDD + GKEV T + TNM TNK FYTDS+GRDF++R+R++R
Sbjct: 163 LYKNKEHAEVEYTIGPIPVDDDDDIGKEVVTRLTTNMATNKIFYTDSNGRDFLERVRNHR 222
Query: 552 SEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHD 731
+W + + QP+AGNYYPVN GIYV DG ELSVLVD ++G SSI+DGQIE+MLHRRL D
Sbjct: 223 DDWDLNLSQPVAGNYYPVNQGIYVADGKYELSVLVDHAVGASSIQDGQIEVMLHRRLSAD 282
Query: 732 DGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQ 911
DG+GV E LNE VC+D++C+GL+
Sbjct: 283 DGRGVGEPLNEVVCVDQKCDGLV------------------------------------- 305
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLAS 1091
D +W ++++AK S ++ YSLPDNVA++TLQ L+DG+ LLR AHL++A ED S +A
Sbjct: 306 DERSWKSNNIAKASTVEGNYSLPDNVAIITLQSLDDGTTLLRLAHLFQAQEDTQYSVMAK 365
Query: 1092 IDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQG-SAADEKVVRGGPVDPSKLV 1268
++L+++F ++ I + ETSLSANQ+++ E K+L W+ G S D ++GGPVD LV
Sbjct: 366 VELRKLFGKRIIKDLTETSLSANQKKS--EMKKLNWRVTGESKTDPAPLKGGPVDSHALV 423
Query: 1269 VELGPMEIRTFIVSF 1313
VELGPMEIRTF++ F
Sbjct: 424 VELGPMEIRTFLLKF 438
Score = 44.3 bits (103), Expect(2) = 5e-89
Identities = 17/25 (68%), Positives = 22/25 (88%)
Frame = +2
Query: 302 LTVLRGPILDEVHQQINSWIYQITR 376
L V+ GP++DEVHQQ +SWIYQ+TR
Sbjct: 138 LKVIHGPLVDEVHQQFSSWIYQVTR 162
>gb|EAL40240.1| ENSANGP00000013227 [Anopheles gambiae str. PEST]
ref|XP_557728.1| ENSANGP00000013227 [Anopheles gambiae str. PEST]
Length = 957
Score = 206 bits (524), Expect(2) = 1e-65
Identities = 119/320 (37%), Positives = 190/320 (59%), Gaps = 10/320 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VY ++ +E E++VGPIP+DD GKE+ + +++ + TF+TDS+GR+ ++R+R+YR
Sbjct: 641 VYAGQEHVELEWLVGPIPIDDSKGKEIISRFESDIKSEGTFWTDSNGREMLRRVRNYRET 700
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W++++ +P+AGNYYP+ I VED ++VL DR+ GGSS+ DGQ+ELM+HRRLL DD
Sbjct: 701 WELDLVEPVAGNYYPITAKIAVEDDHSRMAVLNDRAQGGSSLVDGQLELMVHRRLLRDDA 760
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGA-----RWRRTFGQEIYSPLLLAF 902
GV EALNET + G++ +GK+++ + R ++ P
Sbjct: 761 FGVGEALNET----QYGAGIVARGKHWLFFGSSQKAVSPTLQAKERFLQNKVLLPSWPFV 816
Query: 903 TEQDGGNWANSHVAKFSAMDSTYS--LPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDL 1076
+ D + +++ F + S + LP NV +LTL+ +DG+VL+R HL+E ED
Sbjct: 817 SAVDNVLTYDDYLSNFRNIYSAIAQQLPPNVNLLTLEPWKDGTVLVRLEHLFERNEDPVY 876
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGS---AADEKVVRGGP 1247
S I+++ V I + ET+L+ANQ +A + KRL++ + + A+ + V
Sbjct: 877 SQAVRINVRSVLFALNIESIHETTLAANQWKA--DSKRLQFNTESTANEASPKDQVERVA 934
Query: 1248 VDPSKLVVELGPMEIRTFIV 1307
D + +EL PMEIRTFIV
Sbjct: 935 QDSTDFDIELQPMEIRTFIV 954
Score = 69.7 bits (169), Expect(2) = 1e-65
Identities = 45/129 (34%), Positives = 72/129 (55%), Gaps = 6/129 (4%)
Frame = +2
Query: 23 KSAHIS---SKSTQYSPQGSESSNLQVGQGNLKLQYNEAGKLSLYS-DSKTMVQANFEQK 190
KS ++S SKS+ + + N+ +G L + ++E G +S+ + D +T + +Q
Sbjct: 521 KSYYVSKEESKSSSSAAVMRQEDNVSIGNDYLTVHFDENGFMSMITIDGETH---SLKQN 577
Query: 191 YKYYIGQDGNGSD--PQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
+ YY G GN + ++SGAYIFRPNGT TD V + V++ ++ EVHQ N WI
Sbjct: 578 FLYYEGAYGNNEEFRNRSSGAYIFRPNGTEKAVTD-VVEIQVVKSDLVQEVHQIFNEWIS 636
Query: 365 QITRRLQGE 391
Q+ R G+
Sbjct: 637 QVIRVYAGQ 645
>ref|NP_776986.2| mannosidase, alpha, class 2B, member 1 [Bos taurus]
gb|AAB67726.2| alpha-mannosidase [Bos taurus]
sp|Q29451|MA2B1_BOVIN Lysosomal alpha-mannosidase precursor (Mannosidase, alpha B)
(Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase
alpha class 2B member 1) [Contains: Lysosomal
alpha-mannosidase A peptide; Lysosomal alpha-mannosidase
B peptide; Lysosomal alpha-mannosidase C peptide;
Lysosomal alpha-mannosidase D peptide; Lysosomal
alpha-mannosidase E peptide]
Length = 999
Score = 206 bits (524), Expect(2) = 1e-61
Identities = 124/314 (39%), Positives = 176/314 (56%), Gaps = 3/314 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV DG GKEV + T + T FYTDS+GR+ ++R R+YR
Sbjct: 692 LYPRQRHLELEWTVGPIPVGDGWGKEVISRFDTALATRGLFYTDSNGREILERRRNYRPT 751
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 752 WKLNQTEPVAGNYYPVNSRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDA 811
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSPLLLAFTEQD 914
+GV E LN K+ GL ++G++ V +D + AR R E+ +P ++ +
Sbjct: 812 RGVGEPLN------KEGSGLWVRGRHLVLLDKKETAAARHRLQAEMEVLAPQVV-LAQGG 864
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSLA 1088
G + + LP +V +LTL ++LLR H + GED ++LSS
Sbjct: 865 GARYRLEKAPRTQFSGLRRELPPSVRLLTLARWGPETLLLRLEHQFAVGEDSGRNLSSPV 924
Query: 1089 SIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLV 1268
++DL +F I + ET+L+ANQ A RL+W P P
Sbjct: 925 TLDLTNLFSAFTITNLRETTLAANQLLA--YASRLQWTTDTGPTPHP----SPSRPVSAT 978
Query: 1269 VELGPMEIRTFIVS 1310
+ L PMEIRTF+ S
Sbjct: 979 ITLQPMEIRTFLAS 992
Score = 55.8 bits (133), Expect(2) = 1e-61
Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 1/118 (0%)
Frame = +2
Query: 26 SAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYY 202
S + S+ PQ S S +L + L+ +++ G L + + + Q + +Y
Sbjct: 574 SIYSVSQMPNQRPQKSWSRDLVIQNEYLRARFDPNTGLLMELENLEQNLLLPVRQAFYWY 633
Query: 203 IGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
GN QASGAYIFRPN P+ +++ ++ EVHQ ++W Q+ R
Sbjct: 634 NASTGNNLSSQASGAYIFRPNQNKPLFVSHWAQTHLVKASLVQEVHQNFSAWCSQVVR 691
>gb|AAC48763.1| lysosomal alpha-mannosidase [Bos taurus]
Length = 960
Score = 206 bits (524), Expect(2) = 1e-61
Identities = 124/314 (39%), Positives = 176/314 (56%), Gaps = 3/314 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV DG GKEV + T + T FYTDS+GR+ ++R R+YR
Sbjct: 653 LYPRQRHLELEWTVGPIPVGDGWGKEVISRFDTALATRGLFYTDSNGREILERRRNYRPT 712
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 713 WKLNQTEPVAGNYYPVNSRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDA 772
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSPLLLAFTEQD 914
+GV E LN K+ GL ++G++ V +D + AR R E+ +P ++ +
Sbjct: 773 RGVGEPLN------KEGSGLWVRGRHLVLLDKKETAAARHRLQAEMEVLAPQVV-LAQGG 825
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSLA 1088
G + + LP +V +LTL ++LLR H + GED ++LSS
Sbjct: 826 GARYRLEKAPRTQFSGLRRELPPSVRLLTLARWGPETLLLRLEHQFAVGEDSGRNLSSPV 885
Query: 1089 SIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLV 1268
++DL +F I + ET+L+ANQ A RL+W P P
Sbjct: 886 TLDLTNLFSAFTITNLRETTLAANQLLA--YASRLQWTTDTGPTPHP----SPSRPVSAT 939
Query: 1269 VELGPMEIRTFIVS 1310
+ L PMEIRTF+ S
Sbjct: 940 ITLQPMEIRTFLAS 953
Score = 55.8 bits (133), Expect(2) = 1e-61
Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 1/118 (0%)
Frame = +2
Query: 26 SAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYY 202
S + S+ PQ S S +L + L+ +++ G L + + + Q + +Y
Sbjct: 535 SIYSVSQMPNQRPQKSWSRDLVIQNEYLRARFDPNTGLLMELENLEQNLLLPVRQAFYWY 594
Query: 203 IGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
GN QASGAYIFRPN P+ +++ ++ EVHQ ++W Q+ R
Sbjct: 595 NASTGNNLSSQASGAYIFRPNQNKPLFVSHWAQTHLVKASLVQEVHQNFSAWCSQVVR 652
>emb|CAG12505.1| unnamed protein product [Tetraodon nigroviridis]
Length = 975
Score = 197 bits (502), Expect(2) = 4e-61
Identities = 113/274 (41%), Positives = 169/274 (61%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y +E E+ VGP+PVDD GKEV T + T++ T + FYTDS+GR+ ++R D+R
Sbjct: 704 LYAASRAVELEWTVGPLPVDDNLGKEVITRLDTSISTAQYFYTDSNGREVLQRKTDFRPT 763
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W +E +PIAGNYYP+N +++D +L+V+ DRS GG+SI +G +E+MLHRRLL+DD
Sbjct: 764 WHLEQSEPIAGNYYPINSRAFIKDDVDQLTVVTDRSQGGASIYNGSLEIMLHRRLLYDDN 823
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GV E LNE D EGL+++G+ + +D A R +E+ LL FT DG
Sbjct: 824 RGVGEPLNEV--SDIFPEGLVVRGRLLLSLDRPASAADTYRPLAEEVVLQPLLTFT--DG 879
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
NS + +FS + +LP V +LTL + ++ SVLLR H +++ E K S +++
Sbjct: 880 DLHPNSEL-EFSGL--LAALPPAVHLLTLTQWDESSVLLRLEHQFQSWESKANSQPVTVN 936
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKW 1199
L+++F K+ V E +LSANQ + M KR W
Sbjct: 937 LQKLFSTLKVLGVSELNLSANQWKDKM--KRFDW 968
Score = 62.8 bits (151), Expect(2) = 4e-61
Identities = 36/87 (41%), Positives = 45/87 (51%), Gaps = 3/87 (3%)
Frame = +2
Query: 125 EAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGS-DPQASGAYIFRPNGTV--PISTDGQ 295
+ G LS S+ +T Q + +Y DGN + Q SGAYIFRPNGT PIS Q
Sbjct: 617 DTGLLSGLSNLETQQTIKLTQNFYWYKASDGNSAASKQPSGAYIFRPNGTAPFPISKTAQ 676
Query: 296 VSLTVLRGPILDEVHQQINSWIYQITR 376
+ GP+L EV QQ W Q+ R
Sbjct: 677 TESVQVGGPLLQEVRQQFAPWASQVVR 703
>ref|XP_542048.2| PREDICTED: similar to Lysosomal alpha-mannosidase precursor
(Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase)
(Laman) (Mannosidase alpha class 2B member 1) isoform 1
[Canis familiaris]
Length = 1008
Score = 205 bits (521), Expect(2) = 5e-61
Identities = 133/319 (41%), Positives = 185/319 (57%), Gaps = 8/319 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV DG GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 702 LYPGQRHLELEWTVGPIPVGDGWGKEVISRFDTVLETKGLFYTDSNGREILERRRDYRPT 761
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 762 WKLNQTEPVAGNYYPVNSRIYIRDGHVQLTVLTDRSQGGSSLRDGSVELMVHRRLLKDDG 821
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQ-EIYSPLLLAFTEQD 914
+GV E L E + GL ++G++ V +D A R + E+ +P ++
Sbjct: 822 RGVGEPLLE------EGSGLWVRGRHLVLLDKAQTAATGHRLQAEKEVLAPQVVLAP--- 872
Query: 915 GGNWANSHVA-----KFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDK-DL 1076
G A H+ +FS + LP +V +LTL + +LLR H + GE +L
Sbjct: 873 -GGGAPYHLGVAPRKQFSGL--RRELPPSVHLLTLARWDRTRLLLRLEHQFAVGEGSGNL 929
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQ-GSAADEKVVRGGPVD 1253
SS ++DLK +F I + ET+L+ANQ RA+ RLKW G A R +D
Sbjct: 930 SSPVTLDLKDLFSAFTITYLQETTLAANQPRAS--ASRLKWTPNTGPTAQPSPPR---LD 984
Query: 1254 PSKLVVELGPMEIRTFIVS 1310
P+ + +E PMEIRTF+ S
Sbjct: 985 PTTITLE--PMEIRTFLAS 1001
Score = 55.1 bits (131), Expect(2) = 5e-61
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y GN Q SGAYIFRPN P+ V++ P++ EVHQ ++W
Sbjct: 638 QAFYWYNASVGNNLSTQVSGAYIFRPNRQEPLIVSHWAQTRVVKTPLVQEVHQNFSAWCS 697
Query: 365 QITRRLQGE 391
Q+ R G+
Sbjct: 698 QVVRLYPGQ 706
>ref|XP_867548.1| PREDICTED: similar to Lysosomal alpha-mannosidase precursor
(Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase)
(Laman) (Mannosidase alpha class 2B member 1) isoform 2
[Canis familiaris]
Length = 969
Score = 205 bits (521), Expect(2) = 5e-61
Identities = 133/319 (41%), Positives = 185/319 (57%), Gaps = 8/319 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV DG GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 663 LYPGQRHLELEWTVGPIPVGDGWGKEVISRFDTVLETKGLFYTDSNGREILERRRDYRPT 722
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 723 WKLNQTEPVAGNYYPVNSRIYIRDGHVQLTVLTDRSQGGSSLRDGSVELMVHRRLLKDDG 782
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQ-EIYSPLLLAFTEQD 914
+GV E L E + GL ++G++ V +D A R + E+ +P ++
Sbjct: 783 RGVGEPLLE------EGSGLWVRGRHLVLLDKAQTAATGHRLQAEKEVLAPQVVLAP--- 833
Query: 915 GGNWANSHVA-----KFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDK-DL 1076
G A H+ +FS + LP +V +LTL + +LLR H + GE +L
Sbjct: 834 -GGGAPYHLGVAPRKQFSGL--RRELPPSVHLLTLARWDRTRLLLRLEHQFAVGEGSGNL 890
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQ-GSAADEKVVRGGPVD 1253
SS ++DLK +F I + ET+L+ANQ RA+ RLKW G A R +D
Sbjct: 891 SSPVTLDLKDLFSAFTITYLQETTLAANQPRAS--ASRLKWTPNTGPTAQPSPPR---LD 945
Query: 1254 PSKLVVELGPMEIRTFIVS 1310
P+ + +E PMEIRTF+ S
Sbjct: 946 PTTITLE--PMEIRTFLAS 962
Score = 55.1 bits (131), Expect(2) = 5e-61
Identities = 25/69 (36%), Positives = 36/69 (52%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y GN Q SGAYIFRPN P+ V++ P++ EVHQ ++W
Sbjct: 599 QAFYWYNASVGNNLSTQVSGAYIFRPNRQEPLIVSHWAQTRVVKTPLVQEVHQNFSAWCS 658
Query: 365 QITRRLQGE 391
Q+ R G+
Sbjct: 659 QVVRLYPGQ 667
>emb|CAH91346.1| hypothetical protein [Pongo pygmaeus]
Length = 1012
Score = 202 bits (515), Expect(2) = 9e-61
Identities = 130/317 (41%), Positives = 183/317 (57%), Gaps = 6/317 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 704 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 763
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 764 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 823
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSPLLLAFTEQD 914
+GV+E L E G ++G++ V +D Q A R QE+ +P ++ D
Sbjct: 824 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVV--LAPD 875
Query: 915 GG---NWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLS 1079
GG N +FS + LP +V +LTL VLLR H + GED ++LS
Sbjct: 876 GGAAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLS 933
Query: 1080 SLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPS 1259
+ +++L+ +F I ++ ET+L ANQ R A RLKW + +DP+
Sbjct: 934 APVTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPA 989
Query: 1260 KLVVELGPMEIRTFIVS 1310
+ +E PMEIRTF+ S
Sbjct: 990 NITLE--PMEIRTFLAS 1004
Score = 56.6 bits (135), Expect(2) = 9e-61
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 20 KKSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYK 196
K AH + Q P+ S S L + +++ ++ + G L + + Q +
Sbjct: 588 KPQAH----APQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFF 643
Query: 197 YYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
+Y G+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R
Sbjct: 644 WYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVR 703
Query: 377 RLQGE 391
G+
Sbjct: 704 LYPGQ 708
>gb|EAA44350.2| ENSANGP00000023272 [Anopheles gambiae str. PEST]
ref|XP_314688.2| ENSANGP00000023272 [Anopheles gambiae str. PEST]
Length = 922
Score = 189 bits (480), Expect(2) = 1e-60
Identities = 105/281 (37%), Positives = 170/281 (60%), Gaps = 7/281 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VY ++ +E E++VGPIP+DD GKE+ + +++ + TF+TDS+GR+ ++R+R+YR
Sbjct: 648 VYAGQEHVELEWLVGPIPIDDSKGKEIISRFESDIKSEGTFWTDSNGREMLRRVRNYRET 707
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W++++ +P+AGNYYP+ I VED ++VL DR+ GGSS+ DGQ+ELM+HRRLL DD
Sbjct: 708 WELDLVEPVAGNYYPITAKIAVEDDHSRMAVLNDRAQGGSSLVDGQLELMVHRRLLRDDA 767
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGA-----RWRRTFGQEIYSPLLLAF 902
GV EALNET + G++ +GK+++ + R ++ P
Sbjct: 768 FGVGEALNET----QYGAGIVARGKHWLFFGSSQKAVSPTLQAKERFLQNKVLLPSWPFV 823
Query: 903 TEQDGGNWANSHVAKFSAMDSTYS--LPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDL 1076
+ D + +++ F + S + LP NV +LTL+ +DG+VL+R HL+E ED
Sbjct: 824 SAVDNVLTYDDYLSNFRNIYSAIAQQLPPNVNLLTLEPWKDGTVLVRLEHLFERNEDPVY 883
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKW 1199
S I+++ V I + ET+L+ANQ +A + KRL++
Sbjct: 884 SQAVRINVRSVLFALNIESIHETTLAANQWKA--DSKRLQF 922
Score = 69.7 bits (169), Expect(2) = 1e-60
Identities = 45/129 (34%), Positives = 72/129 (55%), Gaps = 6/129 (4%)
Frame = +2
Query: 23 KSAHIS---SKSTQYSPQGSESSNLQVGQGNLKLQYNEAGKLSLYS-DSKTMVQANFEQK 190
KS ++S SKS+ + + N+ +G L + ++E G +S+ + D +T + +Q
Sbjct: 528 KSYYVSKEESKSSSSAAVMRQEDNVSIGNDYLTVHFDENGFMSMITIDGETH---SLKQN 584
Query: 191 YKYYIGQDGNGSD--PQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
+ YY G GN + ++SGAYIFRPNGT TD V + V++ ++ EVHQ N WI
Sbjct: 585 FLYYEGAYGNNEEFRNRSSGAYIFRPNGTEKAVTD-VVEIQVVKSDLVQEVHQIFNEWIS 643
Query: 365 QITRRLQGE 391
Q+ R G+
Sbjct: 644 QVIRVYAGQ 652
>gb|AAH00736.1| Mannosidase, alpha, class 2B, member 1 [Homo sapiens]
ref|NP_000519.2| mannosidase, alpha, class 2B, member 1 precursor [Homo sapiens]
Length = 1011
Score = 201 bits (510), Expect(2) = 2e-60
Identities = 129/315 (40%), Positives = 182/315 (57%), Gaps = 4/315 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 703 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 762
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 763 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 822
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 823 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 876
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL VLLR H + GED ++LS+
Sbjct: 877 AAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAP 934
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKL 1265
+++L+ +F I ++ ET+L ANQ R A RLKW + +DP+ +
Sbjct: 935 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPANI 990
Query: 1266 VVELGPMEIRTFIVS 1310
+E PMEIRTF+ S
Sbjct: 991 TLE--PMEIRTFLAS 1003
Score = 57.4 bits (137), Expect(2) = 2e-60
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 590 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIG 649
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R G+
Sbjct: 650 DNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQ 707
>gb|AAC34130.1| lysosomal alpha-mannosidase [Homo sapiens]
Length = 1011
Score = 201 bits (510), Expect(2) = 2e-60
Identities = 129/315 (40%), Positives = 182/315 (57%), Gaps = 4/315 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 703 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 762
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 763 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 822
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 823 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 876
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL VLLR H + GED ++LS+
Sbjct: 877 AAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAP 934
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKL 1265
+++L+ +F I ++ ET+L ANQ R A RLKW + +DP+ +
Sbjct: 935 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPANI 990
Query: 1266 VVELGPMEIRTFIVS 1310
+E PMEIRTF+ S
Sbjct: 991 TLE--PMEIRTFLAS 1003
Score = 57.4 bits (137), Expect(2) = 2e-60
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 590 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIG 649
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R G+
Sbjct: 650 DNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQ 707
>gb|AAC51362.1| lysosomal alpha-mannosidase [Homo sapiens]
sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase precursor (Mannosidase, alpha B)
(Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase
alpha class 2B member 1) [Contains: Lysosomal
alpha-mannosidase A peptide; Lysosomal alpha-mannosidase
B peptide; Lysosomal alpha-mannosidase C peptide;
Lysosomal alpha-mannosidase D peptide; Lysosomal
alpha-mannosidase E peptide]
Length = 1010
Score = 201 bits (510), Expect(2) = 2e-60
Identities = 129/315 (40%), Positives = 182/315 (57%), Gaps = 4/315 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 702 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 761
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 762 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 821
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 822 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 875
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL VLLR H + GED ++LS+
Sbjct: 876 AAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAP 933
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKL 1265
+++L+ +F I ++ ET+L ANQ R A RLKW + +DP+ +
Sbjct: 934 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPANI 989
Query: 1266 VVELGPMEIRTFIVS 1310
+E PMEIRTF+ S
Sbjct: 990 TLE--PMEIRTFLAS 1002
Score = 57.4 bits (137), Expect(2) = 2e-60
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 589 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIG 648
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R G+
Sbjct: 649 DNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQ 706
>dbj|BAD93158.1| mannosidase, alpha, class 2B, member 1 precursor variant [Homo
sapiens]
Length = 1007
Score = 201 bits (510), Expect(2) = 2e-60
Identities = 129/315 (40%), Positives = 182/315 (57%), Gaps = 4/315 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 699 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 758
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 759 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 818
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 819 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 872
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL VLLR H + GED ++LS+
Sbjct: 873 AAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAP 930
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKL 1265
+++L+ +F I ++ ET+L ANQ R A RLKW + +DP+ +
Sbjct: 931 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPANI 986
Query: 1266 VVELGPMEIRTFIVS 1310
+E PMEIRTF+ S
Sbjct: 987 TLE--PMEIRTFLAS 999
Score = 57.4 bits (137), Expect(2) = 2e-60
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 586 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIG 645
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R G+
Sbjct: 646 DNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQ 703
>gb|AAC50812.1| lysosomal acid alpha-mannosidase [Homo sapiens]
Length = 988
Score = 201 bits (510), Expect(2) = 2e-60
Identities = 129/315 (40%), Positives = 182/315 (57%), Gaps = 4/315 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 680 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 739
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 740 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 799
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 800 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 853
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL VLLR H + GED ++LS+
Sbjct: 854 AAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAP 911
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKL 1265
+++L+ +F I ++ ET+L ANQ R A RLKW + +DP+ +
Sbjct: 912 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPANI 967
Query: 1266 VVELGPMEIRTFIVS 1310
+E PMEIRTF+ S
Sbjct: 968 TLE--PMEIRTFLAS 980
Score = 57.4 bits (137), Expect(2) = 2e-60
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 567 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIG 626
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R G+
Sbjct: 627 DNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQ 684
>gb|AAB03816.1| alpha-mannosidase
Length = 987
Score = 201 bits (510), Expect(2) = 2e-60
Identities = 129/315 (40%), Positives = 182/315 (57%), Gaps = 4/315 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 679 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 738
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 739 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 798
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 799 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 852
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL VLLR H + GED ++LS+
Sbjct: 853 AAYNLGAPPRTQFSGL--RRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAP 910
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKL 1265
+++L+ +F I ++ ET+L ANQ R A RLKW + +DP+ +
Sbjct: 911 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPANI 966
Query: 1266 VVELGPMEIRTFIVS 1310
+E PMEIRTF+ S
Sbjct: 967 TLE--PMEIRTFLAS 979
Score = 57.4 bits (137), Expect(2) = 2e-60
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 566 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIG 625
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R G+
Sbjct: 626 DNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQ 683
>ref|XP_795985.1| PREDICTED: similar to Lysosomal alpha-mannosidase precursor
(Mannosidase, alpha B) (Lysosomal acid alpha-mannosidase)
(Laman) (Mannosidase alpha class 2B member 1)
[Strongylocentrotus purpuratus]
Length = 1014
Score = 203 bits (517), Expect(2) = 6e-60
Identities = 118/313 (37%), Positives = 182/313 (58%), Gaps = 2/313 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+YK + E + VGPIP+ DG GKE+ T TN+ + + FYTDS+GR +KR+ R +
Sbjct: 710 LYKGQSAAEFTWTVGPIPIGDGLGKEIITRFDTNVQSGQMFYTDSNGRQMMKRVLYQRED 769
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
+ +P+AGNYYP+N I + D + +V+ DRS GGSS+ +G +E+M+HRR+L DD
Sbjct: 770 YPYVNSEPVAGNYYPINSRIIINDTMSQFTVMTDRSQGGSSLSNGSVEIMIHRRILKDDN 829
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIY-SPLLLAFTEQD 914
+GV E LNET + +GL+++G + V + + A +RT G+E+Y P T
Sbjct: 830 RGVGEPLNET---GQFGDGLMVRGTHTVFLATPKKAAYIQRTLGEELYMKPYFYVST--- 883
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASI 1094
A + + S+ + +LP NV +LTL++L+ +LLR H +E G+DK S ++
Sbjct: 884 ----ATGNQSPVSSSFISQALPANVHLLTLEQLKPNVLLLRLEHQFEIGDDKAFSKPVTV 939
Query: 1095 DLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSA-ADEKVVRGGPVDPSKLVV 1271
L+ +F I V E SLSANQ +++ RL+WK +GS+ + + P V
Sbjct: 940 SLRDLFKPFGISDVEELSLSANQVLKSVD--RLQWKIEGSSTTTPQAFKPIPATAPDFNV 997
Query: 1272 ELGPMEIRTFIVS 1310
L PM+IRTF V+
Sbjct: 998 TLNPMDIRTFNVT 1010
Score = 53.1 bits (126), Expect(2) = 6e-60
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 2/71 (2%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGT--VPISTDGQVSLTVLRGPILDEVHQQINSW 358
Q + +Y GN Q SGAYIFRPN + P+ V + V++G ++ EV QQ W
Sbjct: 644 QSFYWYESSTGNNVSIQGSGAYIFRPNKSDPYPLFDGTSVLVKVVKGDVVQEVQQQFTPW 703
Query: 359 IYQITRRLQGE 391
+ Q+ R +G+
Sbjct: 704 LSQVVRLYKGQ 714
>gb|AAL58982.1| lysosomal alpha-mannosidase [Cavia porcellus]
sp|Q8VHC8|MA2B1_CAVPO Lysosomal alpha-mannosidase precursor (Mannosidase, alpha B)
(Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase
alpha class 2B member 1)
Length = 1007
Score = 205 bits (521), Expect(2) = 8e-60
Identities = 128/318 (40%), Positives = 184/318 (57%), Gaps = 7/318 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKE+ + T + T F+TDS+GR+ ++R RDYR
Sbjct: 697 LYSGQRHLELEWTVGPIPVGDKWGKEIISRFDTPLETGGVFFTDSNGREVLERRRDYRPS 756
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG +L+VL DRS GGSS+ DG +ELM+HRRLL DDG
Sbjct: 757 WKLNQTEPVAGNYYPVNSRIYITDGKMQLTVLTDRSQGGSSMSDGSLELMVHRRLLKDDG 816
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQ-EIYSPLLLAFTEQD 914
+GV EAL E G ++G++ + +D E A R + E+ +P L+ Q
Sbjct: 817 RGVGEALQE------PGSGGWVRGRHLLLLDTAREAAAEHRLLAEKELLAPQLVLAPGQG 870
Query: 915 GGNWANSHVA----KFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDL 1076
+ H A +FS + LP +V +LTL ++LLR H + GED ++L
Sbjct: 871 PSYHHDHHEAVPRKQFSGL--RRQLPPSVRLLTLARWGPDTLLLRLEHQFALGEDSSRNL 928
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDP 1256
S ++DL+ +F I ++ ET+L+ANQ RA+ RLKW + V +DP
Sbjct: 929 SLPVTLDLQDLFSTFTITRLQETTLAANQLRAS--ASRLKWTTEIDPISRPAV--PRLDP 984
Query: 1257 SKLVVELGPMEIRTFIVS 1310
S + ++ PMEIRTF+ S
Sbjct: 985 SSITLQ--PMEIRTFVAS 1000
Score = 51.2 bits (121), Expect(2) = 8e-60
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
++S PQ S L + L+ ++ + G LS+ + Q + +Y G
Sbjct: 584 TRSQHSRPQKYSSPVLSIKNEYLRASFHPDTGLLSMIEVLDRKLTLPVNQAFFWYNASVG 643
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRP+ P +++ ++ EVHQ +W Q+ R G+
Sbjct: 644 DKRSSQASGAYIFRPSQQWPFPVSHLARTRLVKTALVQEVHQNFTAWCSQVVRLYSGQ 701
>gb|AAL58984.1| lysosomal alpha-mannosidase [Cavia porcellus]
Length = 1007
Score = 205 bits (521), Expect(2) = 8e-60
Identities = 128/318 (40%), Positives = 184/318 (57%), Gaps = 7/318 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKE+ + T + T F+TDS+GR+ ++R RDYR
Sbjct: 697 LYSGQRHLELEWTVGPIPVGDKWGKEIISRFDTPLETGGVFFTDSNGREVLERRRDYRPS 756
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG +L+VL DRS GGSS+ DG +ELM+HRRLL DDG
Sbjct: 757 WKLNQTEPVAGNYYPVNSRIYITDGKMQLTVLTDRSQGGSSMSDGSLELMVHRRLLKDDG 816
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQ-EIYSPLLLAFTEQD 914
+GV EAL E G ++G++ + +D E A R + E+ +P L+ Q
Sbjct: 817 RGVGEALQE------PGSGGWVRGRHLLLLDTAREAAAEHRLLAEKELLAPQLVLAPGQG 870
Query: 915 GGNWANSHVA----KFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDL 1076
+ H A +FS + LP +V +LTL ++LLR H + GED ++L
Sbjct: 871 PSYHHDHHEAVPRKQFSGL--RRQLPPSVRLLTLARWGPDTLLLRLEHQFALGEDSSRNL 928
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDP 1256
S ++DL+ +F I ++ ET+L+ANQ RA+ RLKW + V +DP
Sbjct: 929 SLPVTLDLQDLFSTFTITRLQETTLAANQLRAS--ASRLKWTTEIDPISRPAV--PRLDP 984
Query: 1257 SKLVVELGPMEIRTFIVS 1310
S + ++ PMEIRTF+ S
Sbjct: 985 SSITLQ--PMEIRTFVAS 1000
Score = 51.2 bits (121), Expect(2) = 8e-60
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
++S PQ S L + L+ ++ + G LS+ + Q + +Y G
Sbjct: 584 TRSQHSRPQKYSSPVLSIKNEYLRASFHPDTGLLSMIEVLDRKLTLPVNQAFFWYNASVG 643
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRP+ P +++ ++ EVHQ +W Q+ R G+
Sbjct: 644 DKRSSQASGAYIFRPSQQWPFPVSHLARTRLVKTALVQEVHQNFTAWCSQVVRLYSGQ 701
>gb|AAL58983.1| lysosomal alpha-mannosidase [Cavia porcellus]
Length = 1007
Score = 205 bits (521), Expect(2) = 8e-60
Identities = 128/318 (40%), Positives = 184/318 (57%), Gaps = 7/318 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKE+ + T + T F+TDS+GR+ ++R RDYR
Sbjct: 697 LYSGQRHLELEWTVGPIPVGDKWGKEIISRFDTPLETGGVFFTDSNGREVLERRRDYRPS 756
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG +L+VL DRS GGSS+ DG +ELM+HRRLL DDG
Sbjct: 757 WKLNQTEPVAGNYYPVNSRIYITDGKMQLTVLTDRSQGGSSMSDGSLELMVHRRLLKDDG 816
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQ-EIYSPLLLAFTEQD 914
+GV EAL E G ++G++ + +D E A R + E+ +P L+ Q
Sbjct: 817 RGVGEALQE------PGSGGWVRGRHLLLLDTAREAAAEHRLLAEKELLAPQLVLAPGQG 870
Query: 915 GGNWANSHVA----KFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDL 1076
+ H A +FS + LP +V +LTL ++LLR H + GED ++L
Sbjct: 871 PSYHHDHHEAVPRKQFSGL--RRQLPPSVRLLTLARWGPDTLLLRLEHQFALGEDSSRNL 928
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDP 1256
S ++DL+ +F I ++ ET+L+ANQ RA+ RLKW + V +DP
Sbjct: 929 SLPVTLDLQDLFSTFTITRLQETTLAANQLRAS--ASRLKWTTEIDPISRPAV--PRLDP 984
Query: 1257 SKLVVELGPMEIRTFIVS 1310
S + ++ PMEIRTF+ S
Sbjct: 985 SSITLQ--PMEIRTFVAS 1000
Score = 51.2 bits (121), Expect(2) = 8e-60
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 1/118 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
++S PQ S L + L+ ++ + G LS+ + Q + +Y G
Sbjct: 584 TRSQHSRPQKYSSPVLSIKNEYLRASFHPDTGLLSMIEVLDRKLTLPVNQAFFWYNASVG 643
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
+ QASGAYIFRP+ P +++ ++ EVHQ +W Q+ R G+
Sbjct: 644 DKRSSQASGAYIFRPSQQWPFPVSHLARTRLVKTALVQEVHQNFTAWCSQVVRLYSGQ 701
>ref|NP_001009222.1| mannosidase, alpha, class 2B, member 1 [Felis catus]
gb|AAB97672.1| lysosomal alpha-mannosidase [Felis catus]
sp|O46432|MA2B1_FELCA Lysosomal alpha-mannosidase precursor (Mannosidase, alpha B)
(Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase
alpha class 2B member 1)
Length = 1007
Score = 198 bits (504), Expect(2) = 5e-59
Identities = 129/316 (40%), Positives = 184/316 (58%), Gaps = 5/316 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ + LE E+ VGPIPV DG GKE+ + T + T FYTDS+GR+ ++R RDYR
Sbjct: 701 LYRGQRHLELEWTVGPIPVGDGWGKEIISRFDTVLETKGLFYTDSNGREILERRRDYRPT 760
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ + +AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 761 WKLNQTETVAGNYYPVNSRIYIRDGNMQLTVLTDRSQGGSSLRDGSMELMVHRRLLKDDG 820
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQ-EIYSPLLLAFTEQD 914
+GV EAL E G ++G++ V +D A R + E+ +P ++
Sbjct: 821 RGVGEALLEDGL------GRWVRGRHLVLLDKVRTAATGHRLQAEKEVLTPQVV--LAPG 872
Query: 915 GGNWANSHVA---KFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDK-DLSS 1082
GG + VA +FS + LP +V +LTL + ++LLR H + GED +LSS
Sbjct: 873 GGAPYHLKVAPRKQFSGL--RRELPPSVHLLTLARWDQKTLLLRLEHQFAVGEDSGNLSS 930
Query: 1083 LASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSK 1262
++DL +F I + ET+L ANQ RA+ RLKW + + +DP+
Sbjct: 931 PVTLDLTDLFSAFTITYLQETTLVANQLRAS--ASRLKWTP--NTGPTPLPSPSRLDPA- 985
Query: 1263 LVVELGPMEIRTFIVS 1310
+ L PMEIRTF+ S
Sbjct: 986 -TITLQPMEIRTFLAS 1000
Score = 55.1 bits (131), Expect(2) = 5e-59
Identities = 24/69 (34%), Positives = 37/69 (53%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y GN Q SGAYIFRPN P+ +++ P++ EVHQ ++W
Sbjct: 637 QAFYWYNASVGNNLSTQVSGAYIFRPNQEKPLMVSHWAQTRLVKTPLVQEVHQNFSAWCS 696
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 697 QVVRLYRGQ 705
>dbj|BAD51966.1| mannosidase, alpha, class 2B, member 1 [Macaca fascicularis]
sp|Q60HE9|MA2B1_MACFA Lysosomal alpha-mannosidase precursor (Mannosidase, alpha B)
(Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase
alpha class 2B member 1)
Length = 1012
Score = 196 bits (499), Expect(2) = 6e-59
Identities = 127/315 (40%), Positives = 180/315 (57%), Gaps = 4/315 (1%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 704 LYPGRRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 763
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 764 WKLNQTEPVAGNYYPVNTRIYITDGKMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDE 823
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 824 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 877
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL +LLR H + GED ++LS+
Sbjct: 878 AAYNLGAPPRTQFSGL--RRELPPSVHLLTLASWGPEMLLLRLEHQFAVGEDSGRNLSAP 935
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKL 1265
+++L+ +F I ++ ET+L ANQ R A RLKW + +DP+ +
Sbjct: 936 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDPANI 991
Query: 1266 VVELGPMEIRTFIVS 1310
+E PMEIRTF+ S
Sbjct: 992 TLE--PMEIRTFLAS 1004
Score = 56.6 bits (135), Expect(2) = 6e-59
Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 591 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQRLLLPVRQTFFWYNASIG 650
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQG 388
+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R G
Sbjct: 651 DNESDQASGAYIFRPNQQKPLPVSRWAQIRLVKTPLVQEVHQNFSAWCSQVVRLYPG 707
>ref|XP_624628.1| PREDICTED: similar to ENSANGP00000013227 [Apis mellifera]
Length = 998
Score = 194 bits (493), Expect(2) = 4e-58
Identities = 118/320 (36%), Positives = 188/320 (58%), Gaps = 10/320 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VY +++E +++VGPIP+ D GKE+ T +N+ ++ FYTDS+GR+ +KR RDYR
Sbjct: 674 VYNGMEYVEFDWLVGPIPIKDMIGKEIITRYYSNLNSSGEFYTDSNGREMLKRKRDYRPT 733
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSK--ELSVLVDRSIGGSSIKDGQIELMLHRRLLHD 731
WK+ + + ++GNYYP+ I ++D + +LS+L DR+ GG+S+KDG+IE+M+HRRLL D
Sbjct: 734 WKVNLQEEVSGNYYPITSKISLKDEERRLKLSLLTDRAQGGTSMKDGEIEMMVHRRLLKD 793
Query: 732 DGKGVAEALNETVCLDKQCEGLIIQGKYYV---KIDPQGEGARWRRTFG-QEIYSPLLLA 899
D GV EALNE+ EGL+++G +Y+ I E A + Q + P
Sbjct: 794 DAFGVGEALNESA----YGEGLVVRGSHYIIGGSIKNLDELAIKEKNLALQLLLRPWPFI 849
Query: 900 FTEQDGGNWANSHVAKF--SAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD 1073
+ + + H +++ S + +LP NV +LTL+ ++ S+LLR H++E E ++
Sbjct: 850 ISNESNFSTYAQHFSQYATSQVSLAKALPPNVHILTLEPWKEDSLLLRLEHIFEIDETEN 909
Query: 1074 LSSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVD 1253
LS +I+++ +F I V ET+L NQ M RLKW A+ + + PV+
Sbjct: 910 LSKPVTINIQDLFKTFTIVSVKETTLGGNQWYKDM--NRLKWDAETNDILYSEEQYQPVE 967
Query: 1254 PSKLVVE--LGPMEIRTFIV 1307
++ L PMEIRTFI+
Sbjct: 968 IKDGIINIILKPMEIRTFIL 987
Score = 56.2 bits (134), Expect(2) = 4e-58
Identities = 35/131 (26%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Frame = +2
Query: 2 HASANLKKSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANF 181
+ S +K++ ++ + G+E N+ V Q N + + K
Sbjct: 558 YKSYTIKRAESARQEAMEEISIGNEFYNIWVNQYN-----------HIVVEWKKEKNMRL 606
Query: 182 EQKYKYYIGQDGNGSD--PQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINS 355
Q + YY G +GN + ++SGAYIFRP + + V +GP+++E+HQ IN
Sbjct: 607 TQSFHYYEGMEGNNMEFKNRSSGAYIFRPRNMFVKNFVTPNTFKVYKGPLVEEIHQYIND 666
Query: 356 WIYQITRRLQG 388
W+ Q+ R G
Sbjct: 667 WVSQVIRVYNG 677
>ref|NP_001014354.1| hypothetical protein LOC541519 [Danio rerio]
gb|AAH91843.1| Hypothetical LOC541519 [Danio rerio]
Length = 982
Score = 203 bits (517), Expect(2) = 2e-57
Identities = 119/310 (38%), Positives = 184/310 (59%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+++ LE E+ VGP+PV+DG GKEV T + T++ ++ FYTDS+GR+ ++R +DYR
Sbjct: 685 LYEDRRELELEWTVGPVPVEDGLGKEVITRLDTDIQSSGYFYTDSNGREVLERRKDYRPT 744
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W ++ +PIAGNYYP+N Y++D ++L+V+ DRS G SSI +G +E+MLHRRLL+DD
Sbjct: 745 WDLKQTEPIAGNYYPINSRAYIKDDKRQLTVVTDRSQGASSIYNGSLEIMLHRRLLYDDF 804
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GV E L+E + GL+ +G+ + + P A R Q + LL+F QDG
Sbjct: 805 RGVGEPLSEP---GEFAHGLVARGRLLLTLSPPEAAADLHRPLAQSMVLQPLLSF--QDG 859
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
+ + +FS + + +LP V +LT+ + + SVL+R H Y+A E K S +++
Sbjct: 860 APSPGTKL-EFSGLQA--ALPPAVHLLTVSQWDQDSVLVRLEHQYQAKESKTHSQPVTVN 916
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLVVEL 1277
L+++F ++ E SL ANQ + M RL W + DPS V L
Sbjct: 917 LQKLFSTLQVLGASEMSLGANQWKEDM--IRLHWNTDALPPTAR-------DPSSWEVTL 967
Query: 1278 GPMEIRTFIV 1307
PMEIRTF++
Sbjct: 968 KPMEIRTFLL 977
Score = 44.7 bits (104), Expect(2) = 2e-57
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Frame = +2
Query: 107 LKLQYNEA-GKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDP-QASGAYIFRPNGTVP- 277
LK+ ++ G LS ++ +T Q + +Y GN + Q SGAYIFRPN + P
Sbjct: 592 LKVTFDSTTGLLSSLTNLETQQTIRLTQNFFWYNASAGNNKESHQPSGAYIFRPNSSDPF 651
Query: 278 -ISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
IS ++ L + EV Q+ + W+ Q+ R
Sbjct: 652 IISKTAEIQAVSLYNSV-QEVTQRFSPWVSQVVR 684
>ref|NP_955436.1| mannosidase 2, alpha B1 [Rattus norvegicus]
gb|AAH61819.1| Mannosidase 2, alpha B1 [Rattus norvegicus]
Length = 1009
Score = 188 bits (477), Expect(2) = 1e-56
Identities = 125/320 (39%), Positives = 178/320 (55%), Gaps = 9/320 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ + LE E+ VGPIPV D GKEV + T M T F+TDS+GR+ +KR D+R
Sbjct: 703 LYEGQRHLELEWTVGPIPVKDDWGKEVISRFNTPMRTRGQFFTDSNGREILKRRDDFRPT 762
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W + +P+AGNYYPVN IY+ DG +L+VL DRS GGSS+ DG +ELM+HRRLL DD
Sbjct: 763 WTLNQTEPVAGNYYPVNTRIYITDGHMQLTVLTDRSQGGSSLLDGSLELMVHRRLLVDDE 822
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGE-GARWRRTFGQEIYSPLLLAFTEQD 914
+GVAE L ET DK ++G++ V + + AR R QE+ +P ++
Sbjct: 823 RGVAEPLLETDTGDK------VRGRHLVILSSVSDAAARHRLLAEQEVLAPQVV--LAHG 874
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSLA 1088
G + +S K LP V +LTL +LLR H + ED ++LSS
Sbjct: 875 GSSPYHSQAPKMQFSALRRELPPQVHLLTLARWGPKMLLLRLEHQFAVKEDSNRNLSSPV 934
Query: 1089 SIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVD---PS 1259
+++L+ +F I + ET+L+ANQ + + RLKW + GP+ PS
Sbjct: 935 TLNLQNLFKTFTINYLQETTLAANQPLSRV--SRLKW----------MTDTGPISYPAPS 982
Query: 1260 KL---VVELGPMEIRTFIVS 1310
+L + L PM+IRTF+ S
Sbjct: 983 RLDPTSITLQPMQIRTFLAS 1002
Score = 57.4 bits (137), Expect(2) = 1e-56
Identities = 30/111 (27%), Positives = 57/111 (51%), Gaps = 1/111 (0%)
Frame = +2
Query: 62 PQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQA 238
P+ S+S L + ++ ++ + G L + + + Q + +Y G+ PQA
Sbjct: 597 PKKSKSRVLVIENKYIRATFDSDTGLLRKIENLEQNISLPVRQGFFWYNASAGDEESPQA 656
Query: 239 SGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
SGAYIFRP+ P+ +T+++ ++ EVHQ ++W Q+ R +G+
Sbjct: 657 SGAYIFRPSHRKPLPVSHWAQVTLVKTNLVQEVHQNFSAWCSQVIRLYEGQ 707
>gb|AAH05430.1| Mannosidase 2, alpha B1 [Mus musculus]
sp|O09159|MA2B1_MOUSE Lysosomal alpha-mannosidase precursor (Mannosidase, alpha B)
(Lysosomal acid alpha-mannosidase) (Laman) (Mannosidase
alpha class 2B member 1)
Length = 1013
Score = 191 bits (486), Expect(2) = 4e-56
Identities = 129/321 (40%), Positives = 180/321 (56%), Gaps = 10/321 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+YK + LE E+ VGPIPV D GKEV + T M T F+TDS+GR+ +KR DYR
Sbjct: 704 LYKGQRHLELEWTVGPIPVRDDWGKEVISRFDTPMKTKGQFFTDSNGREILKRRDDYRPT 763
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W + +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 764 WTLNQTEPVAGNYYPVNTRIYITDGQMQLTVLTDRSQGGSSLQDGSLELMVHRRLLVDDD 823
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGE-GARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L ET DK ++G++ V + + AR R QE+ +P ++L+
Sbjct: 824 RGVSEPLLETDTGDK------VRGRHLVLLSSVSDAAARHRLLAEQEVLAPQVVLSLGGS 877
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD--LSSL 1085
+ + +FS + LP V +LTL +LLR H + ED D LSS
Sbjct: 878 SPYHSRATPKTQFSGL--RQELPPQVHLLTLARWGPKMLLLRLEHQFALKEDSDRNLSSP 935
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPV---DP 1256
+++++ +F I + ET+L+ANQ + RLKW + GP +P
Sbjct: 936 VTLNVQNLFQTFTINYLQETTLAANQPLS--RASRLKW----------MTNTGPTSFPEP 983
Query: 1257 SKL---VVELGPMEIRTFIVS 1310
SKL V L PMEIRTF+ S
Sbjct: 984 SKLDPTSVTLKPMEIRTFLAS 1004
Score = 52.4 bits (124), Expect(2) = 4e-56
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y G+ QASGAYIFRPN PI +++++ ++ EVHQ ++W
Sbjct: 640 QGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCS 699
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 700 QVIRLYKGQ 708
>dbj|BAE28235.1| unnamed protein product [Mus musculus]
dbj|BAB23588.1| unnamed protein product [Mus musculus]
Length = 1013
Score = 191 bits (486), Expect(2) = 4e-56
Identities = 129/321 (40%), Positives = 180/321 (56%), Gaps = 10/321 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+YK + LE E+ VGPIPV D GKEV + T M T F+TDS+GR+ +KR DYR
Sbjct: 704 LYKGQRHLELEWTVGPIPVRDDWGKEVISRFDTPMKTKGQFFTDSNGREILKRRDDYRPT 763
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W + +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 764 WTLNQTEPVAGNYYPVNTRIYITDGQMQLTVLTDRSQGGSSLQDGSLELMVHRRLLVDDD 823
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGE-GARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L ET DK ++G++ V + + AR R QE+ +P ++L+
Sbjct: 824 RGVSEPLLETDTGDK------VRGRHLVLLSSVSDAAARHRLLAEQEVLAPQVVLSLGGS 877
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD--LSSL 1085
+ + +FS + LP V +LTL +LLR H + ED D LSS
Sbjct: 878 SPYHSRATPKTQFSGL--RQELPPQVHLLTLARWGPKMLLLRLEHQFALKEDSDRNLSSP 935
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPV---DP 1256
+++++ +F I + ET+L+ANQ + RLKW + GP +P
Sbjct: 936 VTLNVQNLFQTFTINYLQETTLAANQPLS--RASRLKW----------MTNTGPTSYPEP 983
Query: 1257 SKL---VVELGPMEIRTFIVS 1310
SKL V L PMEIRTF+ S
Sbjct: 984 SKLDPTSVTLKPMEIRTFLAS 1004
Score = 52.4 bits (124), Expect(2) = 4e-56
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y G+ QASGAYIFRPN PI +++++ ++ EVHQ ++W
Sbjct: 640 QGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCS 699
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 700 QVIRLYKGQ 708
>dbj|BAE42288.1| unnamed protein product [Mus musculus]
Length = 1013
Score = 191 bits (486), Expect(2) = 4e-56
Identities = 129/321 (40%), Positives = 180/321 (56%), Gaps = 10/321 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+YK + LE E+ VGPIPV D GKEV + T M T F+TDS+GR+ +KR DYR
Sbjct: 704 LYKGQRHLELEWTVGPIPVRDDWGKEVISRFDTPMKTKGQFFTDSNGREILKRRDDYRPT 763
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W + +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 764 WTLNQTEPVAGNYYPVNTRIYITDGQMQLTVLTDRSQGGSSLQDGSLELMVHRRLLVDDD 823
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGE-GARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L ET DK ++G++ V + + AR R QE+ +P ++L+
Sbjct: 824 RGVSEPLLETDTGDK------VRGRHLVLLSSVSDAAARHRLLAEQEVLAPQVVLSLGGS 877
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD--LSSL 1085
+ + +FS + LP V +LTL +LLR H + ED D LSS
Sbjct: 878 SPYHSRATPKTQFSGL--RQELPPQVHLLTLARWGPKMLLLRLEHQFALKEDSDRNLSSP 935
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPV---DP 1256
+++++ +F I + ET+L+ANQ + RLKW + GP +P
Sbjct: 936 VTLNVQNLFQTFTINYLQETTLAANQPLS--RASRLKW----------MTNTGPTSFPEP 983
Query: 1257 SKL---VVELGPMEIRTFIVS 1310
SKL V L PMEIRTF+ S
Sbjct: 984 SKLDPTSVTLKPMEIRTFLAS 1004
Score = 52.4 bits (124), Expect(2) = 4e-56
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y G+ QASGAYIFRPN PI +++++ ++ EVHQ ++W
Sbjct: 640 QGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCS 699
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 700 QVIRLYKGQ 708
>gb|AAC78560.1| lysosomal alpha-mannosidase [Mus musculus]
ref|NP_034894.1| mannosidase 2, alpha B1 [Mus musculus]
Length = 1012
Score = 191 bits (486), Expect(2) = 4e-56
Identities = 129/321 (40%), Positives = 180/321 (56%), Gaps = 10/321 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+YK + LE E+ VGPIPV D GKEV + T M T F+TDS+GR+ +KR DYR
Sbjct: 703 LYKGQRHLELEWTVGPIPVRDDWGKEVISRFDTPMKTKGQFFTDSNGREILKRRDDYRPT 762
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W + +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 763 WTLNQTEPVAGNYYPVNTRIYITDGQMQLTVLTDRSQGGSSLQDGSLELMVHRRLLVDDD 822
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGE-GARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L ET DK ++G++ V + + AR R QE+ +P ++L+
Sbjct: 823 RGVSEPLLETDTGDK------VRGRHLVLLSSVSDAAARHRLLAEQEVLAPQVVLSLGGS 876
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD--LSSL 1085
+ + +FS + LP V +LTL +LLR H + ED D LSS
Sbjct: 877 SPYHSRATPKTQFSGL--RQELPPQVHLLTLARWGPKMLLLRLEHQFALKEDSDRNLSSP 934
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPV---DP 1256
+++++ +F I + ET+L+ANQ + RLKW + GP +P
Sbjct: 935 VTLNVQNLFQTFTINYLQETTLAANQPLS--RASRLKW----------MTNTGPTSFPEP 982
Query: 1257 SKL---VVELGPMEIRTFIVS 1310
SKL V L PMEIRTF+ S
Sbjct: 983 SKLDPTSVTLKPMEIRTFLAS 1003
Score = 52.4 bits (124), Expect(2) = 4e-56
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y G+ QASGAYIFRPN PI +++++ ++ EVHQ ++W
Sbjct: 639 QGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCS 698
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 699 QVIRLYKGQ 707
>gb|AAC09470.1| lysosomal alpha-mannosidase [Mus musculus]
Length = 992
Score = 191 bits (486), Expect(2) = 4e-56
Identities = 129/321 (40%), Positives = 180/321 (56%), Gaps = 10/321 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+YK + LE E+ VGPIPV D GKEV + T M T F+TDS+GR+ +KR DYR
Sbjct: 683 LYKGQRHLELEWTVGPIPVRDDWGKEVISRFDTPMKTKGQFFTDSNGREILKRRDDYRPT 742
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W + +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 743 WTLNQTEPVAGNYYPVNTRIYITDGQMQLTVLTDRSQGGSSLQDGSLELMVHRRLLVDDD 802
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGE-GARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L ET DK ++G++ V + + AR R QE+ +P ++L+
Sbjct: 803 RGVSEPLLETDTGDK------VRGRHLVLLSSVSDAAARHRLLAEQEVLAPQVVLSLGGS 856
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD--LSSL 1085
+ + +FS + LP V +LTL +LLR H + ED D LSS
Sbjct: 857 SPYHSRATPKTQFSGL--RQELPPQVHLLTLARWGPKMLLLRLEHQFALKEDSDRNLSSP 914
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPV---DP 1256
+++++ +F I + ET+L+ANQ + RLKW + GP +P
Sbjct: 915 VTLNVQNLFQTFTINYLQETTLAANQPLS--RASRLKW----------MTNTGPTSFPEP 962
Query: 1257 SKL---VVELGPMEIRTFIVS 1310
SKL V L PMEIRTF+ S
Sbjct: 963 SKLDPTSVTLKPMEIRTFLAS 983
Score = 52.4 bits (124), Expect(2) = 4e-56
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y G+ QASGAYIFRPN PI +++++ ++ EVHQ ++W
Sbjct: 619 QGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCS 678
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 679 QVIRLYKGQ 687
>gb|AAC53369.1| alpha-D-mannosidase
Length = 991
Score = 191 bits (486), Expect(2) = 4e-56
Identities = 129/321 (40%), Positives = 180/321 (56%), Gaps = 10/321 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+YK + LE E+ VGPIPV D GKEV + T M T F+TDS+GR+ +KR DYR
Sbjct: 682 LYKGQRHLELEWTVGPIPVRDDWGKEVISRFDTPMKTKGQFFTDSNGREILKRRDDYRPT 741
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W + +P+AGNYYPVN IY+ DG +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 742 WTLNQTEPVAGNYYPVNTRIYITDGQMQLTVLTDRSQGGSSLQDGSLELMVHRRLLVDDD 801
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGE-GARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L ET DK ++G++ V + + AR R QE+ +P ++L+
Sbjct: 802 RGVSEPLLETDTGDK------VRGRHLVLLSSVSDAAARHRLLAEQEVLAPQVVLSLGGS 855
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD--LSSL 1085
+ + +FS + LP V +LTL +LLR H + ED D LSS
Sbjct: 856 SPYHSRATPKTQFSGL--RQELPPQVHLLTLARWGPKMLLLRLEHQFALKEDSDRNLSSP 913
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPV---DP 1256
+++++ +F I + ET+L+ANQ + RLKW + GP +P
Sbjct: 914 VTLNVQNLFQTFTINYLQETTLAANQPLS--RASRLKW----------MTNTGPTSFPEP 961
Query: 1257 SKL---VVELGPMEIRTFIVS 1310
SKL V L PMEIRTF+ S
Sbjct: 962 SKLDPTSVTLKPMEIRTFLAS 982
Score = 52.4 bits (124), Expect(2) = 4e-56
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y G+ QASGAYIFRPN PI +++++ ++ EVHQ ++W
Sbjct: 618 QGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCS 677
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 678 QVIRLYKGQ 686
>ref|NP_723591.1| CG6206-PB, isoform B [Drosophila melanogaster]
gb|AAN10754.1| CG6206-PB, isoform B [Drosophila melanogaster]
Length = 1080
Score = 176 bits (447), Expect(2) = 7e-54
Identities = 101/269 (37%), Positives = 154/269 (57%), Gaps = 8/269 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VY + + E E++VGPIP+DDG GKEV T +++ ++ F TDS+GR+ IKR ++R
Sbjct: 699 VYNKDSYAEFEWLVGPIPIDDGIGKEVITRFNSDIASDGIFRTDSNGREMIKRKINHRDT 758
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W +++++ +AGNYYP+ I VED + +++L DR+ GGSS+KDG +ELM+HRRLL DD
Sbjct: 759 WSVKINEAVAGNYYPITTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDA 818
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYV----KIDPQGEGARWRRTFGQ-EIYSPLLLAF 902
GV EALNET + +GLI +GK+++ D +G + Q E P F
Sbjct: 819 FGVGEALNET----EYGDGLIARGKHHLFFGKSTDREGVSLKGIERLTQLEKLLPTWKFF 874
Query: 903 TEQD---GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD 1073
+ + W + FS + + LP V +LTL+ + +L+RF H+ E GED
Sbjct: 875 SNMEDYSADEWQTAFTNIFSGI--SLVLPKPVHLLTLEPWHENQLLVRFEHIMENGEDAS 932
Query: 1074 LSSLASIDLKRVFPEKKIGKVIETSLSAN 1160
S ++K V + + ET+L N
Sbjct: 933 YSQPVQFNVKNVLSAFDVEGIRETTLDGN 961
Score = 59.7 bits (143), Expect(2) = 7e-54
Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 4/104 (3%)
Frame = +2
Query: 77 SSNLQVGQGNLKLQYNEAGKLS-LYSDSKTMVQANFEQKYKYYIGQDGNGSD--PQASGA 247
SS +G +++L ++ G LS + +D T + + Q++ +Y G GN ++ ++SGA
Sbjct: 599 SSVTVIGNSHIQLGFDTNGFLSEVTADGLTRLVS---QEFLFYEGAVGNNAEFLNRSSGA 655
Query: 248 YIFRPN-GTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
YIFRPN + +TD QV + V +G ++ EVHQ+ N WI Q+ R
Sbjct: 656 YIFRPNENKIHFATD-QVEIEVYKGDLVHEVHQKFNDWISQVVR 698
>ref|NP_609408.1| CG6206-PA, isoform A [Drosophila melanogaster]
gb|AAF52958.2| CG6206-PA, isoform A [Drosophila melanogaster]
gb|AAD38576.1| BcDNA.GH02419 [Drosophila melanogaster]
Length = 1080
Score = 176 bits (447), Expect(2) = 7e-54
Identities = 101/269 (37%), Positives = 154/269 (57%), Gaps = 8/269 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
VY + + E E++VGPIP+DDG GKEV T +++ ++ F TDS+GR+ IKR ++R
Sbjct: 699 VYNKDSYAEFEWLVGPIPIDDGIGKEVITRFNSDIASDGIFRTDSNGREMIKRKINHRDT 758
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W +++++ +AGNYYP+ I VED + +++L DR+ GGSS+KDG +ELM+HRRLL DD
Sbjct: 759 WSVKINEAVAGNYYPITTKIDVEDDTARMAILTDRAQGGSSLKDGSLELMVHRRLLKDDA 818
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYV----KIDPQGEGARWRRTFGQ-EIYSPLLLAF 902
GV EALNET + +GLI +GK+++ D +G + Q E P F
Sbjct: 819 FGVGEALNET----EYGDGLIARGKHHLFFGKSTDREGVSLKGIERLTQLEKLLPTWKFF 874
Query: 903 TEQD---GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKD 1073
+ + W + FS + + LP V +LTL+ + +L+RF H+ E GED
Sbjct: 875 SNMEDYSADEWQTAFTNIFSGI--SLVLPKPVHLLTLEPWHENQLLVRFEHIMENGEDAS 932
Query: 1074 LSSLASIDLKRVFPEKKIGKVIETSLSAN 1160
S ++K V + + ET+L N
Sbjct: 933 YSQPVQFNVKNVLSAFDVEGIRETTLDGN 961
Score = 59.7 bits (143), Expect(2) = 7e-54
Identities = 38/104 (36%), Positives = 63/104 (60%), Gaps = 4/104 (3%)
Frame = +2
Query: 77 SSNLQVGQGNLKLQYNEAGKLS-LYSDSKTMVQANFEQKYKYYIGQDGNGSD--PQASGA 247
SS +G +++L ++ G LS + +D T + + Q++ +Y G GN ++ ++SGA
Sbjct: 599 SSVTVIGNSHIQLGFDTNGFLSEVTADGLTRLVS---QEFLFYEGAVGNNAEFLNRSSGA 655
Query: 248 YIFRPN-GTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
YIFRPN + +TD QV + V +G ++ EVHQ+ N WI Q+ R
Sbjct: 656 YIFRPNENKIHFATD-QVEIEVYKGDLVHEVHQKFNDWISQVVR 698
>pir||JC2200 alpha-mannosidase (EC 3.2.1.24) precursor - human
Length = 961
Score = 179 bits (453), Expect(2) = 1e-53
Identities = 122/318 (38%), Positives = 173/318 (54%), Gaps = 7/318 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV D GKEV + T + T FYTDS+GR+ ++R RDYR
Sbjct: 652 LYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPT 711
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKE-LSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
WK+ +P+A NYYPVN IY+ DG+ + L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 712 WKLNQTEPVAANYYPVNTRIYITDGNMQLLTVLTDRSQGGSSLRDGSLELMVHRRLLKDD 771
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSPLLLAFTEQ 911
G+GV+E L E G ++G++ V +D Q A R QE+ +P ++
Sbjct: 772 GRGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAP-- 823
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS---VLLRFAHLYEAGED--KDL 1076
G + A S T+ G VLLR H + GED ++L
Sbjct: 824 --GGAPPTISGLLRARSSQGCAGTCRPRCTVSRWPAGDPEMVLLRLEHQFAVGEDSGRNL 881
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDP 1256
S+ +++L+ +F I ++ ET+L ANQ R A RLKW + +DP
Sbjct: 882 SAPVTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGPTPHQTPY--QLDP 937
Query: 1257 SKLVVELGPMEIRTFIVS 1310
+ + +E PMEIRTF+ S
Sbjct: 938 ANITLE--PMEIRTFLAS 953
Score = 57.0 bits (136), Expect(2) = 1e-53
Identities = 32/123 (26%), Positives = 58/123 (47%), Gaps = 1/123 (0%)
Frame = +2
Query: 26 SAHISSKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYY 202
S + + Q P+ S S L + +++ ++ + G L + + Q + +Y
Sbjct: 534 SLEAQAAAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWY 593
Query: 203 IGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRL 382
G+ QASGAYIFRPN P+ + +++ P++ EVHQ ++W Q+ R
Sbjct: 594 NASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLY 653
Query: 383 QGE 391
G+
Sbjct: 654 PGQ 656
>dbj|BAD93831.1| alpha-mannosidase [Arabidopsis thaliana]
Length = 180
Score = 211 bits (538), Expect = 5e-53
Identities = 105/167 (62%), Positives = 130/167 (77%), Gaps = 3/167 (1%)
Frame = +3
Query: 825 IDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTL 1004
IDP GEGA+WRRTFGQEIYSPLLLAF +QD G + A FS +D +YSLPDNVA+LTL
Sbjct: 1 IDPYGEGAKWRRTFGQEIYSPLLLAFAQQDDGKPMSFGAASFSGIDPSYSLPDNVALLTL 60
Query: 1005 QELEDGSVLLRFAHLYEAGEDKDLSSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEK 1184
QEL+DG+VLLR AHLYE EDK+LS +AS++LK++FP KKIGK+ E SLSANQER+ MEK
Sbjct: 61 QELDDGNVLLRLAHLYEVEEDKELSGVASVELKKLFPGKKIGKLTEMSLSANQERSTMEK 120
Query: 1185 KRLKWKAQGSAA---DEKVVRGGPVDPSKLVVELGPMEIRTFIVSFD 1316
KRL WK +G + ++K RG +DP KL +EL PMEIRT ++ +
Sbjct: 121 KRLVWKVEGEGSYGEEKKAKRGREIDPRKLEMELYPMEIRTVLIHLE 167
>gb|EAL32868.1| GA21810-PA [Drosophila pseudoobscura]
Length = 1008
Score = 179 bits (455), Expect(2) = 1e-50
Identities = 110/320 (34%), Positives = 178/320 (55%), Gaps = 10/320 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ + +E E+++GPIP D+ +E+ T + + +N FYTDS+GR+ IKR +D R +
Sbjct: 698 IYEGVNRVEFEWLIGPIPTDEDTAREIVTIFDSGISSNGVFYTDSNGRELIKRTKDKRED 757
Query: 558 WKIEV-HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
+ ++ QPI+GNYYPV I ++D +K +++L DR+ GG+S+KDGQ+ELMLHRRL+ DD
Sbjct: 758 FNPDLGRQPISGNYYPVVSRIALQDSNKRIALLNDRAQGGTSMKDGQLELMLHRRLIRDD 817
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQD 914
G GV EALNE K + LI +GK Y+ ++ E + R +EI P + F++
Sbjct: 818 GYGVGEALNE----QKYDKPLIARGKVYLILNSVEESTKVERVAEKEILLPFSVFFSKAS 873
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASI 1094
+ S +AK A+ S P +V +LTL+ D +LLR + + E ++ S
Sbjct: 874 SQSQTQSAIAK--AVPSFDDFPQSVHLLTLEPFTDDEILLRVENFLDHTE----GNVVSF 927
Query: 1095 DLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQG---------SAADEKVVRGGP 1247
+++ +F ++ ET+L N + M + + A G + A +
Sbjct: 928 NIRHIFETLGGVEIRETTLDGNLPLSEMRRFKFHHDASGHSPAAVEYFTTAHTPLAAVDS 987
Query: 1248 VDPSKLVVELGPMEIRTFIV 1307
+ S V L PM+IRTFI+
Sbjct: 988 QEASDFSVTLHPMQIRTFII 1007
Score = 46.2 bits (108), Expect(2) = 1e-50
Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 1/123 (0%)
Frame = +2
Query: 23 KSAHISSKSTQYSPQGSESSNLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYY 202
K H K ++ SE+ +Q Q L + N G+L + V + +Q + Y
Sbjct: 591 KKVHSMKKVETHADDDSETV-VQTSQIKLVID-NNTGRLKTVEMNG--VSESVDQNFAIY 646
Query: 203 IGQDGNGSDPQASGAYIFRPNGTVPIST-DGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
+ SGAY+FR V + + +V TV G ++ EVHQQ N WI Q+ R
Sbjct: 647 --------ETYESGAYVFRQKEDVDLKLLEDKVEFTVYDGSLVKEVHQQFNEWISQVIRI 698
Query: 380 LQG 388
+G
Sbjct: 699 YEG 701
>gb|ABC86349.1| IP13633p [Drosophila melanogaster]
Length = 968
Score = 165 bits (418), Expect(2) = 1e-48
Identities = 105/326 (32%), Positives = 178/326 (54%), Gaps = 11/326 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y++ + +E E++VGPIP DD GKE+ T +N+ + FYTDS+GR+ ++R R+ R
Sbjct: 659 IYEDVNRVEFEWLVGPIPTDDDVGKEIITRFSSNISSKGKFYTDSNGREILERERNQREH 718
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
+ ++ + I+GNYYPV I ++D K +++L DR+ GG+S+KDG++ELMLHRRLL+DD
Sbjct: 719 FTPDMSEAISGNYYPVTGQISLQDDEKRITLLNDRAQGGTSLKDGELELMLHRRLLNDDA 778
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
GV EALNET + GLI +GK Y+ +D +G +R ++ F++ +G
Sbjct: 779 FGVGEALNET----QYGTGLIARGKIYLILDAV-DGKPNQRLLQHQLDQHFWKFFSKSNG 833
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
N ++ + + +P++V +L+L+ +L+R + G ++ S +
Sbjct: 834 VASVNRNM-----IPDFFGIPESVELLSLEPYSKDQILIRLENFNTEG------NVVSFN 882
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGS-----------AADEKVVRGG 1244
+ +F ++ ET+L N + KR K+ G+ A +
Sbjct: 883 IYPLFESLDGYQIWETTLDGNM--LLEDVKRFKFAQDGTGSIPSSVEYYHAPHNPLTANS 940
Query: 1245 PVDPSKLVVELGPMEIRTFIVSFDHI 1322
++ S VV L PM+IRTFI+ +I
Sbjct: 941 TMNASGFVVTLVPMQIRTFIIQQKYI 966
Score = 53.5 bits (127), Expect(2) = 1e-48
Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Frame = +2
Query: 176 NFEQKYKYYIGQDGNGSDPQ--ASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQI 349
N +Q + Y G GN + + +SGAY+FRP G + I + +V L+ G + EVHQ +
Sbjct: 591 NIQQTFGIYKGYRGNNGESKNRSSGAYVFRPYGDIEI-VNNKVELSFYNGTKVKEVHQHV 649
Query: 350 NSWIYQITR 376
N WI Q+ R
Sbjct: 650 NEWISQVIR 658
>ref|NP_609407.1| CG5322-PA [Drosophila melanogaster]
gb|AAF52957.1| CG5322-PA [Drosophila melanogaster]
Length = 950
Score = 165 bits (418), Expect(2) = 1e-48
Identities = 105/326 (32%), Positives = 178/326 (54%), Gaps = 11/326 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y++ + +E E++VGPIP DD GKE+ T +N+ + FYTDS+GR+ ++R R+ R
Sbjct: 641 IYEDVNRVEFEWLVGPIPTDDDVGKEIITRFSSNISSKGKFYTDSNGREILERERNQREH 700
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
+ ++ + I+GNYYPV I ++D K +++L DR+ GG+S+KDG++ELMLHRRLL+DD
Sbjct: 701 FTPDMSEAISGNYYPVTGQISLQDDEKRITLLNDRAQGGTSLKDGELELMLHRRLLNDDA 760
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
GV EALNET + GLI +GK Y+ +D +G +R ++ F++ +G
Sbjct: 761 FGVGEALNET----QYGTGLIARGKIYLILDAV-DGKPNQRLLQHQLDQHFWKFFSKSNG 815
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
N ++ + + +P++V +L+L+ +L+R + G ++ S +
Sbjct: 816 VASVNRNM-----IPDFFGIPESVELLSLEPYSKDQILIRLENFNTEG------NVVSFN 864
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGS-----------AADEKVVRGG 1244
+ +F ++ ET+L N + KR K+ G+ A +
Sbjct: 865 IYPLFESLDGYQIWETTLDGNM--LLEDVKRFKFAQDGTGSIPSSVEYYHAPHNPLTANS 922
Query: 1245 PVDPSKLVVELGPMEIRTFIVSFDHI 1322
++ S VV L PM+IRTFI+ +I
Sbjct: 923 TMNASGFVVTLVPMQIRTFIIQQKYI 948
Score = 53.5 bits (127), Expect(2) = 1e-48
Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 2/69 (2%)
Frame = +2
Query: 176 NFEQKYKYYIGQDGNGSDPQ--ASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQI 349
N +Q + Y G GN + + +SGAY+FRP G + I + +V L+ G + EVHQ +
Sbjct: 573 NIQQTFGIYKGYRGNNGESKNRSSGAYVFRPYGDIEI-VNNKVELSFYNGTKVKEVHQHV 631
Query: 350 NSWIYQITR 376
N WI Q+ R
Sbjct: 632 NEWISQVIR 640
>ref|XP_629747.1| alpha-mannosidase [Dictyostelium discoideum]
gb|EAL61313.1| alpha-mannosidase [Dictyostelium discoideum]
Length = 1010
Score = 181 bits (459), Expect(2) = 6e-48
Identities = 110/320 (34%), Positives = 172/320 (53%), Gaps = 9/320 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y D LE E I+GPI + DG GKE+ + T +VT++T+Y+DS G + KRI +YR
Sbjct: 699 LYSNADHLEVEEIIGPIDISDGIGKEIVSRYTTTLVTDQTWYSDSQGMEMQKRITNYRPS 758
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKEL--SVLVDRSIGGSSIKDGQIELMLHRRLLHD 731
W + V QP +GNY PVN Y++D ++ L +++ DRS G +S++DGQ+++M+HRR L D
Sbjct: 759 WNLTVVQPTSGNYVPVNAIAYIQDPNQSLQFTIVTDRSRGCASLRDGQLDMMMHRRTLKD 818
Query: 732 DGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAF--T 905
DG+GV + +NE+ I+ + D R + PLL F T
Sbjct: 819 DGRGVGQPMNEST--------QIVTTSKLIFHDISSYAQSHYRPAALSLSHPLLPMFTTT 870
Query: 906 EQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQEL--EDGSVLLRFAHLYEA-GEDKDL 1076
+Q +W + + +S + S LP+ + + TLQ L +D ++LLR ++Y+ G+D
Sbjct: 871 QQSSNDWNSQYQGVYSPLTSASPLPNGLKIQTLQWLDNQDNTILLRIENIYQIDGQDSQD 930
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWK-AQGSAADEKVVRGGPVD 1253
++DL +F I E +L+ Q+ + + RLKWK G D K D
Sbjct: 931 PQTITLDLSTIFSTITITSATEMNLTGVQKLSNL--SRLKWKTVDGKNYDHKSSSSTKED 988
Query: 1254 PSK-LVVELGPMEIRTFIVS 1310
S V PM+IRTFI++
Sbjct: 989 SSNGFVFTFSPMQIRTFIIT 1008
Score = 35.4 bits (80), Expect(2) = 6e-48
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Frame = +2
Query: 122 NEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP--NGTVPISTDGQ 295
++ G + ++ + V ++ Q+Y +Y GN Q SGAYIFRP + P + +
Sbjct: 613 SQDGSILSITNKTSGVTSSITQEYIWYNPSVGNDDSAQCSGAYIFRPVEDFAYPYN-NAT 671
Query: 296 VSLTVLRGPILDEVHQ 343
S++++RG I + +
Sbjct: 672 PSVSIIRGEISSSIRR 687
>pdb|1O7D|D Chain D, The Structure Of The Bovine Lysosomal A-Mannosidase
Suggests A Novel Mechanism For Low Ph Activation
Length = 282
Score = 160 bits (405), Expect(2) = 8e-47
Identities = 85/182 (46%), Positives = 118/182 (64%), Gaps = 1/182 (0%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV DG GKEV + T + T FYTDS+GR+ ++R R+YR
Sbjct: 101 LYPRQRHLELEWTVGPIPVGDGWGKEVISRFDTALATRGLFYTDSNGREILERRRNYRPT 160
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DD
Sbjct: 161 WKLNQTEPVAGNYYPVNSRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDA 220
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSPLLLAFTEQD 914
+GV E LN K+ GL ++G++ V +D + AR R E+ +P ++ Q
Sbjct: 221 RGVGEPLN------KEGSGLWVRGRHLVLLDKKETAAARHRLQAEMEVLAPQVV--LAQG 272
Query: 915 GG 920
GG
Sbjct: 273 GG 274
Score = 52.4 bits (124), Expect(2) = 8e-47
Identities = 23/64 (35%), Positives = 34/64 (53%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y GN QASGAYIFRPN P+ +++ ++ EVHQ ++W
Sbjct: 37 QAFYWYNASTGNNLSSQASGAYIFRPNQNKPLFVSHWAQTHLVKASLVQEVHQNFSAWCS 96
Query: 365 QITR 376
Q+ R
Sbjct: 97 QVVR 100
>ref|NP_609251.1| CG9465-PA [Drosophila melanogaster]
gb|AAF52709.1| CG9465-PA [Drosophila melanogaster]
Length = 942
Score = 171 bits (434), Expect(2) = 1e-46
Identities = 111/323 (34%), Positives = 177/323 (54%), Gaps = 13/323 (4%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ +E E++VGPIP+DD G E T + + +N FYTDS+GR+ +KR++D R +
Sbjct: 632 IYEGVSRVELEWMVGPIPIDDKLGSEFVTNFKSEISSNGVFYTDSNGRELMKRVKDKRED 691
Query: 558 WKIEV-HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
+ ++ QP++GN+YPV I ++D +K L +L DRS GG+S++DG +E+++HRR L +D
Sbjct: 692 FVSDLSRQPVSGNFYPVTSRIALQDDTKRLVLLNDRSQGGASLEDGALEMLIHRRHLFND 751
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEG-ARWRRTFGQEIYSPLLLAFTEQ 911
G GV EALNET + +GLI +GK Y+ +D +G R +E++ P F++
Sbjct: 752 GGGVGEALNET----QYGKGLIARGKLYLILDSATDGDTVTERKTEKELFLPFWKFFSKT 807
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLAS 1091
G + ++ LP +V +LTL+ + +L+RF H DK + S
Sbjct: 808 GG-----VEITPSKSLPDFNDLPQSVHLLTLEFFSEQEILIRFEHFL----DKSEGRVIS 858
Query: 1092 IDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQG----------SAADEKVVRG 1241
+++ +F + ET+L N + M KR K+ AQ S A K +
Sbjct: 859 FNIRDIFDSLGGLAIRETTLDGNMPLSDM--KRFKFHAQESGTKPSSVEYSTAQHKPLEA 916
Query: 1242 GPVDPSKL-VVELGPMEIRTFIV 1307
D + L V L PM+IRTFI+
Sbjct: 917 VKSDEASLFAVTLYPMQIRTFII 939
Score = 40.4 bits (93), Expect(2) = 1e-46
Identities = 19/50 (38%), Positives = 28/50 (56%)
Frame = +2
Query: 239 SGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQG 388
S AY FR +G + + + TV G ++ EVHQ +N WI Q+ R +G
Sbjct: 587 SCAYTFRQDGDIELF-ENDFEFTVYEGSLVKEVHQHVNDWISQVIRIYEG 635
>ref|XP_512408.1| PREDICTED: similar to Mannosidase, alpha, class 2B, member 1 [Pan
troglodytes]
Length = 1076
Score = 157 bits (397), Expect(2) = 2e-44
Identities = 118/322 (36%), Positives = 165/322 (51%), Gaps = 11/322 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y + LE E+ VGPIPV RDYR
Sbjct: 796 LYPGQRHLELEWSVGPIPVG----------------------------------RDYRPT 821
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
WK+ +P+AGNYYPVN IY+ DG+ +L+VL DRS GGSS++DG +ELM+HRRLL DDG
Sbjct: 822 WKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDG 881
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKID-PQGEGARWRRTFGQEIYSP-LLLAFTEQ 911
+GV+E L E G ++G++ V +D Q A R QE+ +P ++LA
Sbjct: 882 RGVSEPLME------NGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 935
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSL 1085
N +FS + LP +V +LTL VLLR H + GED ++LS+
Sbjct: 936 AAYNLGAPPRTQFSGL--RRDLPPSVHLLTLAIWGPEMVLLRLEHQFAVGEDSGRNLSAP 993
Query: 1086 ASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGG------- 1244
+++L+ +F I ++ ET+L ANQ R A RLKW A +VRG
Sbjct: 994 VTLNLRDLFSTFTITRLQETTLVANQLREA--ASRLKWTTNTGGA---LVRGPTPHQTPY 1048
Query: 1245 PVDPSKLVVELGPMEIRTFIVS 1310
+DP+ + +E PMEIRTF+ S
Sbjct: 1049 QLDPANITLE--PMEIRTFLAS 1068
Score = 47.4 bits (111), Expect(2) = 2e-44
Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 19/136 (13%)
Frame = +2
Query: 41 SKSTQYSPQGSESSNLQVGQGNLKLQYN-EAGKLSLYSDSKTMVQANFEQKYKYYIGQDG 217
+++ Q P+ S S L + +++ ++ + G L + + Q + +Y G
Sbjct: 665 ARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIG 724
Query: 218 NGSDPQASGAYIFRPN--GTVPISTDGQVSLT----VLR------------GPILDEVHQ 343
+ QASGAYIFRPN +P+S Q+ L +LR P++ EVHQ
Sbjct: 725 DNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKDSPLLRYRLTSTSPVCPQTPLVQEVHQ 784
Query: 344 QINSWIYQITRRLQGE 391
++W Q+ R G+
Sbjct: 785 NFSAWCSQVVRLYPGQ 800
>sp|P34098|MANA_DICDI Lysosomal alpha-mannosidase precursor (Alpha-D-mannoside
mannohydrolase) (Laman) [Contains: Alpha-mannosidase 60
kDa subunit; Alpha-mannosidase 58 kDa subunit]
gb|AAA33224.1| alpha-mannosidase
Length = 1005
Score = 169 bits (427), Expect(2) = 3e-44
Identities = 97/282 (34%), Positives = 156/282 (55%), Gaps = 7/282 (2%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y D LE E I+GPI + DG GKE+ + T +VT++T+Y+DS G + KRI +YR
Sbjct: 699 LYSNADHLEVEEIIGPIDISDGIGKEIVSRYTTTLVTDQTWYSDSQGMEMQKRITNYRPS 758
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKEL--SVLVDRSIGGSSIKDGQIELMLHRRLLHD 731
W + V QP +GNY PVN Y++D ++ L +++ DRS G +S++DGQ+++M+HRR L D
Sbjct: 759 WNLTVVQPTSGNYVPVNAIAYIQDPNQSLQFTIVTDRSRGCASLRDGQLDMMMHRRTLKD 818
Query: 732 DGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAF--T 905
DG+GV + +NE+ I+ + D R + PLL F T
Sbjct: 819 DGRGVGQPMNEST--------QIVTTSKLIFHDISSYAQSHYRPAALSLSHPLLPMFTTT 870
Query: 906 EQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQEL--EDGSVLLRFAHLYEA-GEDKDL 1076
+Q +W + + +S + S LP+ + + TLQ L +D ++LLR ++Y+ G+D
Sbjct: 871 QQSSNDWNSQYQGVYSPLTSASPLPNGLKIQTLQWLDNQDNTILLRIENIYQIDGQDSQD 930
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWK 1202
++DL +F I E +L+ Q+ + + RLKWK
Sbjct: 931 PQTITLDLSTIFSTITITSATEMNLTGVQKLSNL--SRLKWK 970
Score = 35.4 bits (80), Expect(2) = 3e-44
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Frame = +2
Query: 122 NEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP--NGTVPISTDGQ 295
++ G + ++ + V ++ Q+Y +Y GN Q SGAYIFRP + P + +
Sbjct: 613 SQDGSILSITNKTSGVTSSITQEYIWYNPSVGNDDSAQCSGAYIFRPVEDFAYPYN-NAT 671
Query: 296 VSLTVLRGPILDEVHQ 343
S++++RG I + +
Sbjct: 672 PSVSIIRGEISSSIRR 687
>ref|NP_609252.1| CG9466-PA [Drosophila melanogaster]
gb|AAL13500.1| GH02475p [Drosophila melanogaster]
gb|AAF52710.1| CG9466-PA [Drosophila melanogaster]
Length = 982
Score = 181 bits (458), Expect = 1e-43
Identities = 114/325 (35%), Positives = 184/325 (56%), Gaps = 12/325 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+ ++K ++E E++VGPIPV++ G EV T + + +N FYTDS+GR+ I+R +D R +
Sbjct: 673 ISEDKPYVEFEWLVGPIPVEEEFGTEVVTIFSSEIASNGVFYTDSNGRELIRREKDKRED 732
Query: 558 WKIEVH-QPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
+ E+ QP +GNYYP+ I ++D +K L++L DR+ GG+S+KDGQIELMLHRRL+ DD
Sbjct: 733 FTPELAVQPTSGNYYPITSRIALQDSNKRLAILNDRAQGGTSMKDGQIELMLHRRLVRDD 792
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQD 914
G GV EALNE +K + LI +GK ++ ++ E R +E + PL F++
Sbjct: 793 GYGVGEALNE----EKYGQPLIARGKVFLILNAADESTSAEREAEKEFHLPLWKFFSKNT 848
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASI 1094
G S A ++ S P +V +LTL+ D +LLR + + E K + S
Sbjct: 849 G-----STTAAAKSVPSFDDFPKSVHLLTLEPFNDDEILLRVENFKDHIEGK----VVSF 899
Query: 1095 DLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGS-----------AADEKVVRG 1241
+++ +F ++ ET+L N + M K+ K+ A+GS ++ + +
Sbjct: 900 NIRPIFDYLNGVEIRETTLDGNLPLSDM--KQFKFHAEGSGIRGSEPEYYTSSHKPLSAN 957
Query: 1242 GPVDPSKLVVELGPMEIRTFIVSFD 1316
D ++ V L PM+IRTFI+ +
Sbjct: 958 QTQDAAEFAVTLYPMQIRTFIIKHE 982
>ref|XP_701739.1| PREDICTED: hypothetical protein XP_696647 [Danio rerio]
Length = 609
Score = 157 bits (396), Expect(2) = 2e-43
Identities = 85/215 (39%), Positives = 136/215 (63%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+++ LE E+ VGP+PV+DG GKEV T + T++ ++ FYTDS+GR+ ++R +DYR
Sbjct: 391 LYEDRRELELEWTVGPVPVEDGLGKEVITRLDTDIQSSGYFYTDSNGREVLERRKDYRPT 450
Query: 558 WKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
W ++ +PIAGNYYP+N Y++D ++L+V+ DRS G SSI +G +E+MLHRRLL+DD
Sbjct: 451 WDLKQTEPIAGNYYPINSRAYIKDDKRQLTVVTDRSQGASSIYNGSLEIMLHRRLLYDDF 510
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
+GV E L+ + GL+ +G+ + + P A R Q + +L+F QDG
Sbjct: 511 RGVGEPLSAP---GEFAHGLVARGRLLLTLSPPEAAADLHRPLAQSMVVQPVLSF--QDG 565
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDG 1022
A ++ +FS + + +LP V +LT+ + G
Sbjct: 566 APSAGINL-EFSGLQA--ALPPAVHLLTVSQWGSG 597
Score = 44.7 bits (104), Expect(2) = 2e-43
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Frame = +2
Query: 107 LKLQYNEA-GKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDP-QASGAYIFRPNGTVP- 277
LK+ ++ G LS ++ +T Q + +Y GN + Q SGAYIFRPN + P
Sbjct: 298 LKVTFDSTTGLLSSLTNLETQQTIRLTQNFFWYNASAGNNKESHQPSGAYIFRPNSSDPF 357
Query: 278 -ISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
IS ++ L + EV Q+ + W+ Q+ R
Sbjct: 358 IISKTAEIQAVSLYNSV-QEVTQRFSPWVSQVVR 390
>ref|NP_609250.2| CG9463-PA [Drosophila melanogaster]
gb|AAF52708.2| CG9463-PA [Drosophila melanogaster]
Length = 1003
Score = 165 bits (417), Expect(2) = 2e-43
Identities = 108/323 (33%), Positives = 178/323 (55%), Gaps = 13/323 (4%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ + +E E++VGP+P+DD GKE+ T + + + FYTDS+GR+ ++R +D R +
Sbjct: 693 IYEGVNRVEFEWLVGPVPIDDELGKEIVTIFKSGISSGGVFYTDSNGREMMRREKDKRED 752
Query: 558 WKIEV-HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
+ ++ QP++GNYYPV + ++D SK + +L DRS GG+S++DG++E+MLHRR + D
Sbjct: 753 FSPDLSEQPVSGNYYPVTSRMALQDSSKRMVLLNDRSQGGASLEDGRLEMMLHRRHIFAD 812
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGA-RWRRTFGQEIYSPLLLAFTEQ 911
G G AEA+NE + +GLI +GK ++ ++ +GA R +EI+ P F++
Sbjct: 813 GSGAAEAINE----QQFGKGLIARGKLFLYLNAIEDGATASERVAEKEIHLPFWKFFSK- 867
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLAS 1091
N S V K + LP +V +LTL+ +LLR + + E ++ S
Sbjct: 868 --SNNIQSDVTK--TLSDFNDLPQSVHLLTLEPYSKDEILLRLENFLDQTE----GNVVS 919
Query: 1092 IDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKV-----------VR 1238
++++F + ++ ET+L N + M KRLK+ GS V
Sbjct: 920 FSIRQIFDDLGGLEIRETTLDGNLPLSDM--KRLKFHHDGSGPSHSVPEYFTSLHKPLAA 977
Query: 1239 GGPVDPSKLVVELGPMEIRTFIV 1307
D S+ V L PM+IRTFI+
Sbjct: 978 DKTQDASEFSVTLKPMQIRTFII 1000
Score = 36.2 bits (82), Expect(2) = 2e-43
Identities = 18/47 (38%), Positives = 25/47 (53%)
Frame = +2
Query: 248 YIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQG 388
YIFR + + + D TV G + EVHQ +N WI Q+ R +G
Sbjct: 651 YIFRQDADLELVEDA-FDFTVYDGESVKEVHQHVNEWISQVIRIYEG 696
>gb|AAL48871.2| RE28991p [Drosophila melanogaster]
Length = 1016
Score = 162 bits (411), Expect(2) = 1e-42
Identities = 107/323 (33%), Positives = 177/323 (54%), Gaps = 13/323 (4%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ + +E E++VGP+P+DD GKE+ T + + + FYTDS+GR+ ++R +D R +
Sbjct: 706 IYEGVNRVEFEWLVGPVPIDDELGKEIVTIFKSGISSGGVFYTDSNGREMMRREKDKRED 765
Query: 558 WKIEV-HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
+ ++ QP++GNYY V + ++D SK + +L DRS GG+S++DG++E+MLHRR + D
Sbjct: 766 FSPDLSEQPVSGNYYQVTSRVALQDSSKRMVLLNDRSQGGASLEDGRLEMMLHRRHIFAD 825
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGA-RWRRTFGQEIYSPLLLAFTEQ 911
G G AEA+NE + +GLI +GK ++ ++ +GA R +EI+ P F++
Sbjct: 826 GSGAAEAINE----QQFGKGLIARGKLFLYLNAIEDGATASERVAEKEIHLPFWKFFSK- 880
Query: 912 DGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLAS 1091
N S V K + LP +V +LTL+ +LLR + + E ++ S
Sbjct: 881 --SNNIQSDVTK--TLSDFNDLPQSVHLLTLEPYSKDEILLRLENFLDQTE----GNVVS 932
Query: 1092 IDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKV-----------VR 1238
++++F + ++ ET+L N + M KRLK+ GS V
Sbjct: 933 FSIRQIFDDLGGLEIRETTLDGNLPLSDM--KRLKFHHDGSGPSHSVPEYFTSLHKPLAA 990
Query: 1239 GGPVDPSKLVVELGPMEIRTFIV 1307
D S+ V L PM+IRTFI+
Sbjct: 991 DKTQDASEFSVTLKPMQIRTFII 1013
Score = 36.2 bits (82), Expect(2) = 1e-42
Identities = 18/47 (38%), Positives = 25/47 (53%)
Frame = +2
Query: 248 YIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQG 388
YIFR + + + D TV G + EVHQ +N WI Q+ R +G
Sbjct: 664 YIFRQDADLELVEDA-FDFTVYDGESVKEVHQHVNEWISQVIRIYEG 709
>emb|CAE68642.1| Hypothetical protein CBG14532 [Caenorhabditis briggsae]
Length = 918
Score = 129 bits (323), Expect(2) = 2e-41
Identities = 94/291 (32%), Positives = 145/291 (49%), Gaps = 15/291 (5%)
Frame = +3
Query: 363 IRLPGVYKEKDFLETEFIVGPIPVDDGNG--KEVATEIVTNMVTNKTFYTDSSGRDFIKR 536
+RLP K K+++E E+IVGPIP + N KE T T + + YTDS+GR +KR
Sbjct: 616 VRLP---KNKNYVEFEWIVGPIPKEFKNPVTKEFVTRYTTEINSKSVSYTDSNGRQVMKR 672
Query: 537 IRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHR 716
D + + + +P+AGNYYP+ Y++D + SV+ DR+ G +G +E+MLHR
Sbjct: 673 YFDGATSFDYDDTEPVAGNYYPITSFGYIKDDKNQFSVITDRA-QGMMANEGVVEIMLHR 731
Query: 717 RLLHDDGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLL 896
R +DD GV EAL+E K GL+ +GK+ V E A R E + +L
Sbjct: 732 RCFYDDHFGVEEALDEP---GKDGRGLVAKGKHIVLFTDLEESAAQLRPLVAENFHQPVL 788
Query: 897 AFTEQDGGNWANSHVAKF------SAMDSTYSLPDNVAMLTLQELED-----GSVLLRFA 1043
AF + NS++ KF + + + P + LT++ LE+ +VLLRF
Sbjct: 789 AF-------YNNSNLEKFEFNRQLESPERIHEFPPWLNFLTIEMLENRVDGKNNVLLRFE 841
Query: 1044 HLYEAGEDKDLSSLAS--IDLKRVFPEKKIGKVIETSLSANQERAAMEKKR 1190
H+Y K +DL +F K+ + + +L N++ K R
Sbjct: 842 HIYHNDSAKAAKYAVPQILDLDNLFKSFKLDFLEKMTLGGNKKLLETGKNR 892
Score = 65.9 bits (159), Expect(2) = 2e-41
Identities = 35/100 (35%), Positives = 56/100 (56%)
Frame = +2
Query: 77 SSNLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIF 256
S N + +L ++ G L+ + KT + + Q++ +Y G D D Q SGAYIF
Sbjct: 520 SGNTTITNEHLIATFDNRGYLTSLQNRKTGLLKSIRQEFFFYEGIDSK--DDQPSGAYIF 577
Query: 257 RPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITR 376
RP PI+ D ++ L V++G + +EV Q+IN ++ QI R
Sbjct: 578 RPKSQQPIAFDSKIELEVVKGSVTNEVRQKINPYVSQIVR 617
>gb|AAM50967.1| RE08556p [Drosophila melanogaster]
Length = 1007
Score = 166 bits (420), Expect = 3e-39
Identities = 107/320 (33%), Positives = 172/320 (53%), Gaps = 10/320 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ K+ +E E+ VGPI ++ G+EV + + +N YTDS+GR+ IKR++D R
Sbjct: 698 IYEGKNLVEIEWQVGPIEREEEFGREVVIIFNSTIASNGVSYTDSNGREMIKRVKDQRET 757
Query: 558 WKIEV-HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
+ + QP A NYYPV I ++D K ++VL DR+ GG+S+ +GQ+ELMLHRRL+ DD
Sbjct: 758 FTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQGGASMLNGQLELMLHRRLVRDD 817
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQD 914
G GV EALNE +K + +I +GK Y+ + P E R +EI+ P F++
Sbjct: 818 GYGVGEALNE----EKYGQPMIARGKVYLILSPSDESTAAEREAEKEIHLPFWKFFSKNT 873
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASI 1094
G S A ++ S P +V +LTL+ D VLLR + + E + S
Sbjct: 874 G-----STTAAAKSVPSFNDFPKSVHLLTLEPFNDDEVLLRVENFLDHTE----GQVVSF 924
Query: 1095 DLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQG---------SAADEKVVRGGP 1247
+++ +F ++ ET+L N + M++ + + G ++A + +
Sbjct: 925 NIRPIFDYLNGVEIRETTLDGNLPLSDMKRFKFHHDSSGQKPDAVEYFTSAHKPLAAEQS 984
Query: 1248 VDPSKLVVELGPMEIRTFIV 1307
+ S+ V L PM+IRTFI+
Sbjct: 985 QEASEFSVTLHPMQIRTFII 1004
>gb|EAS02484.1| Glycosyl hydrolases family 38 protein [Tetrahymena thermophila SB210]
Length = 850
Score = 153 bits (387), Expect(2) = 3e-39
Identities = 103/310 (33%), Positives = 173/310 (55%), Gaps = 6/310 (1%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E + PI + DG GKE+ + TN+ KTFYTDS+G KRI ++R W ++VH+
Sbjct: 559 VEVETFIDPINISDGKGKEIVMIVNTNLKNKKTFYTDSNGLSLQKRILNFRPTWDLKVHE 618
Query: 579 PIAGNYYPVNLGIYVEDGSK--ELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
++GNYYP+ I ++D K ++SV+ DRS GG+S+K+GQ+ELM+HRR+L DD +GV E
Sbjct: 619 QVSGNYYPIGSMIQIQDEDKKEQISVVNDRSQGGTSLKEGQLELMIHRRILRDDNRGVGE 678
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWAN 932
+LNET KQ GL + ++Y+ + Q G RR + SPL+ F E D G + N
Sbjct: 679 SLNETDNESKQI-GLFQKIRHYIVFESQ-NGQLSRRVQNELDASPLIF-FAESDKG-FFN 734
Query: 933 SHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASIDLKRVF 1112
V K +++ + + + L+ +D L LY ++++ A+ ++ F
Sbjct: 735 FKVNK--NVNNIFKNSNIYLRVYLKIYQDHYTL----RLYNVNDNQE----ANFEIPSNF 784
Query: 1113 PEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLV----VELG 1280
+ E +L+ANQ + +K++KW+ + K+ + +D K + ++L
Sbjct: 785 QIME-----ELTLTANQSKQDWYQKQMKWEDENG----KIYQQKQIDLKKEIEQKNIKLK 835
Query: 1281 PMEIRTFIVS 1310
P+++R F V+
Sbjct: 836 PLQLRVFQVN 845
Score = 33.9 bits (76), Expect(2) = 3e-39
Identities = 16/59 (27%), Positives = 33/59 (55%)
Frame = +2
Query: 152 DSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPIL 328
+++ + + +F +Y +Y +G Q+SGAYIFRP+ + ++T+ RG ++
Sbjct: 479 EAQKLKEYSFSLQYNFYYSSQNSG---QSSGAYIFRPDNDQTHTYSEIKNITIYRGQLV 534
>ref|NP_609253.1| CG9468-PA [Drosophila melanogaster]
gb|AAF52711.2| CG9468-PA [Drosophila melanogaster]
Length = 1007
Score = 164 bits (415), Expect = 1e-38
Identities = 106/320 (33%), Positives = 172/320 (53%), Gaps = 10/320 (3%)
Frame = +3
Query: 378 VYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSE 557
+Y+ K+ +E E+ VGPI ++ G+EV + + ++ YTDS+GR+ IKR++D R
Sbjct: 698 IYEGKNLVEIEWQVGPIEREEEFGREVVIIFNSTIASDGVSYTDSNGREMIKRVKDQRET 757
Query: 558 WKIEV-HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
+ + QP A NYYPV I ++D K ++VL DR+ GG+S+ +GQ+ELMLHRRL+ DD
Sbjct: 758 FTPGLDRQPTAANYYPVTSRIALQDSKKRIAVLNDRAQGGASMLNGQLELMLHRRLVRDD 817
Query: 735 GKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQD 914
G GV EALNE +K + +I +GK Y+ + P E R +EI+ P F++
Sbjct: 818 GYGVGEALNE----EKYGQPMIARGKVYLILSPSDESTAAEREAEKEIHLPFWKFFSKNT 873
Query: 915 GGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASI 1094
G S A ++ S P +V +LTL+ D VLLR + + E + S
Sbjct: 874 G-----STTAAAKSVPSFNDFPKSVHLLTLEPFNDDEVLLRVENFLDHTE----GQVVSF 924
Query: 1095 DLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQG---------SAADEKVVRGGP 1247
+++ +F ++ ET+L N + M++ + + G ++A + +
Sbjct: 925 NIRPIFDYLNGVEIRETTLDGNLPLSDMKRFKFHHDSSGQKPDAVEYFTSAHKPLAAEQS 984
Query: 1248 VDPSKLVVELGPMEIRTFIV 1307
+ S+ V L PM+IRTFI+
Sbjct: 985 QEASEFSVTLHPMQIRTFII 1004
>gb|EAS02485.1| Glycosyl hydrolases family 38 protein [Tetrahymena thermophila SB210]
Length = 1197
Score = 145 bits (367), Expect(2) = 2e-36
Identities = 96/272 (35%), Positives = 152/272 (55%), Gaps = 2/272 (0%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E + PI V DG GKEV + TN+ KTFYTDS+G KRI ++R W + VHQ
Sbjct: 920 VEVETFIHPINVSDGKGKEVVMIVNTNLKNKKTFYTDSNGLSLQKRILNFRPTWDLRVHQ 979
Query: 579 PIAGNYYPVNLGIYV--EDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
++GNYYP+ I + ED ++++SV+ DRS GG+S+K+GQ+ELM+HRR L DD +GV E
Sbjct: 980 EVSGNYYPIGSMIQIQDEDTNQQISVVNDRSQGGTSLKEGQLELMIHRRTLQDDNRGVGE 1039
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWAN 932
+LNE + ++ GL + ++Y+ + Q G RR + SPL+ F E D G + N
Sbjct: 1040 SLNE-IDIESGQNGLSQKIRHYIVFESQ-NGQLSRRVQNELDASPLIF-FAESDKGLF-N 1095
Query: 933 SHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASIDLKRVF 1112
V K + N+ + ++ G LR LY ++++ A+ ++ F
Sbjct: 1096 FKVDKNL---NKIIKNSNIYLRVYLKIYQGHYTLR---LYNVNDNQE----ANFEIPSNF 1145
Query: 1113 PEKKIGKVIETSLSANQERAAMEKKRLKWKAQ 1208
+ E +L+ANQ + +K++KW+ +
Sbjct: 1146 QIME-----ELTLTANQSKQDWYQKQMKWQGE 1172
Score = 32.0 bits (71), Expect(2) = 2e-36
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Frame = +2
Query: 35 ISSKSTQYSPQGSESSNLQVGQGNLKLQYN--EAGKLSLYSDSKTMVQANFEQKYKYYIG 208
I S Q + S+ S L+V Y E K S + K + + F +Y +Y
Sbjct: 800 IKSLQEQVVIELSKLSTLKVDLIKQSFLYQVWETEKQSSFEVQK-LKEYTFSLQYNFYYS 858
Query: 209 QDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPIL 328
G Q+SGAYIFRP+ + ++T+ RG ++
Sbjct: 859 SQNWG---QSSGAYIFRPDNDQTYTYSQIKNITIYRGQLV 895
>gb|EAR94085.1| Glycosyl hydrolases family 38 protein [Tetrahymena thermophila SB210]
Length = 1047
Score = 149 bits (376), Expect = 3e-34
Identities = 109/325 (33%), Positives = 170/325 (52%), Gaps = 12/325 (3%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E +G IP++D GKEV I T ++ N+TFYTDS+G + KRI +YR W + V++
Sbjct: 743 VELETFIGSIPIEDKVGKEVVLLINTPVINNQTFYTDSNGLELQKRILNYRPTWNLSVNE 802
Query: 579 PIAGNYYPVNLGIYVED--GSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
P +GNYYPVN I ++D +K +S++ DRS GG+S+++GQ+ELM+HRRLL DD +GV E
Sbjct: 803 PSSGNYYPVNGMITIQDINSNKRISLVNDRSQGGTSLQEGQLELMIHRRLLFDDARGVGE 862
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWAN 932
LNET + GL + ++Y+ + +G+ R+ P++ Q
Sbjct: 863 PLNETEPYNNS-TGLTQRVRHYIVFE-EGDQTLSRKIQTHVDTYPIVFQSLSQ------- 913
Query: 933 SHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLR-FAHLYEAGEDKDLSSLASIDLKRV 1109
+A + LP+ L V R F LY L++L +D
Sbjct: 914 ------TANFNNVRLPNRFNPLKTNTDPFLKVYYRPFGDLYLL----RLNNLNEVDASSY 963
Query: 1110 FPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADE-KVVRGGPVDP--------SK 1262
+ + V E +L+ANQ + E+KR KW + S+ K ++ +K
Sbjct: 964 TLPEGVEIVEEVTLTANQNKKEWEEKRYKWTIENSSEQNLKFSESSRLNRLLSQAEQYNK 1023
Query: 1263 LVVELGPMEIRTFIVSFDHISDKQQ 1337
L V+ P+E+R FIVSF+ + +QQ
Sbjct: 1024 LYVK--PLELRAFIVSFNAGTSQQQ 1046
Score = 35.0 bits (79), Expect = 9.2
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Frame = +2
Query: 32 HISSKSTQYSPQGSESSNLQVGQGNLKLQYNEAGKLSLYSDSKTMVQA--NFEQKYKYYI 205
H+S + + S+ +L V + N + + + +D + V +FE Y YY
Sbjct: 617 HVSFQKKSQKVKVSDKVSLTVNRFNTIFKLKTCSRRTSENDEENSVCTVNDFEVLYHYYP 676
Query: 206 GQDGNGSDPQASGAYIFRP 262
G G Q SGAY+FRP
Sbjct: 677 AYQGQG---QKSGAYVFRP 692
>ref|XP_812205.1| lysosomal alpha-mannosidase precursor [Trypanosoma cruzi strain CL
Brener]
gb|EAN90354.1| lysosomal alpha-mannosidase precursor, putative [Trypanosoma cruzi]
Length = 977
Score = 134 bits (338), Expect(2) = 2e-33
Identities = 79/259 (30%), Positives = 134/259 (51%), Gaps = 17/259 (6%)
Frame = +3
Query: 393 DFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEV 572
D ++ EF IP+ D G+E+ T++ + FYTDS+GR+ +R D+RS++
Sbjct: 679 DLVDVEFTSFGIPIHDNFGRELVARFRTSVESGDVFYTDSNGREMQRRRVDHRSDYPFTQ 738
Query: 573 HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
+P+AGN+YPV ++ D + +V D +GG+S++ G++ ++HRRLL DD KGV E
Sbjct: 739 TEPVAGNFYPVTSVFFINDTQTQFNVFPDAPMGGTSLQSGEVLFVVHRRLLRDDFKGVGE 798
Query: 753 ALNETVCLDKQCE---------------GLIIQGKYYVKIDPQGEGA--RWRRTFGQEIY 881
LNET + + L ++G + G A R R + Y
Sbjct: 799 PLNETAFVTSYADCVMTNTSNCGHHYGPPLRVRGTLSFSVSRSGPTAMRRVREQQDENYY 858
Query: 882 SPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAG 1061
+PL++ + A S +A+++ +SLP ++ ++TLQ ++ ++LLR H Y
Sbjct: 859 TPLVMFSSSSTD---AASTIARYNT-SFGFSLPPSLQVVTLQLIDQQNLLLRLGHRYAVS 914
Query: 1062 EDKDLSSLASIDLKRVFPE 1118
ED + S +DL +F E
Sbjct: 915 EDPERSLPVEVDLMTIFKE 933
Score = 33.5 bits (75), Expect(2) = 2e-33
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L++ L L++ G + + + +Q + YYI DG+ GAYI RP
Sbjct: 577 DLEISNEALVLKFGRNGLIQSVTVRSSGQTVAVKQDWCYYISNDGDTVSLSPGGAYIMRP 636
Query: 263 --NGTVPISTDGQVSLTVL 313
N T TD V L ++
Sbjct: 637 VSNATCNPITDSPVELRLV 655
>ref|XP_819105.1| lysosomal alpha-mannosidase precursor [Trypanosoma cruzi strain CL
Brener]
gb|AAD16005.1| lysosomal acid alpha-mannosidase precursor [Trypanosoma cruzi]
gb|EAN97254.1| lysosomal alpha-mannosidase precursor, putative [Trypanosoma cruzi]
Length = 977
Score = 134 bits (336), Expect(2) = 6e-33
Identities = 79/259 (30%), Positives = 133/259 (51%), Gaps = 17/259 (6%)
Frame = +3
Query: 393 DFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEV 572
D ++ EF IP+ D G+E+ T++ + FYTDS+GR+ +R D+RS++
Sbjct: 679 DLVDVEFTSFGIPIHDNFGRELVARFRTSVESGDVFYTDSNGREMQRRRVDHRSDYPFTQ 738
Query: 573 HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
+P+AGN+YPV ++ D + +V D +GG+S++ G++ ++HRRLL DD KGV E
Sbjct: 739 TEPVAGNFYPVTSVFFINDTQTQFNVFPDAPMGGTSLQSGEVLFVVHRRLLRDDFKGVEE 798
Query: 753 ALNETVCLDKQCE---------------GLIIQGKYYVKIDPQGEGA--RWRRTFGQEIY 881
LNET + + L ++G + G A R R + Y
Sbjct: 799 PLNETAFVTSYADCVMANTSNCGHHYGPPLRVRGTLSFSVSRSGPTAMRRVREQQDENYY 858
Query: 882 SPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAG 1061
+PL++ + A S +A+++ +SLP ++ ++TLQ ++ +LLR H Y
Sbjct: 859 TPLVMFSSSSTD---AASAIARYNT-SFGFSLPPSLQVVTLQLIDQQKLLLRLGHRYAVS 914
Query: 1062 EDKDLSSLASIDLKRVFPE 1118
ED + S +DL +F E
Sbjct: 915 EDPERSLPVEVDLMTIFKE 933
Score = 32.3 bits (72), Expect(2) = 6e-33
Identities = 21/79 (26%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L++ L L++ G + + + +Q + YYI +G+ GAYI RP
Sbjct: 577 DLEISNEALVLKFGRNGLIESVTVRSSGQTVAVKQDWCYYISNNGDTVSSSPGGAYIMRP 636
Query: 263 --NGTVPISTDGQVSLTVL 313
N T TD V L ++
Sbjct: 637 VSNATCNPITDSPVELRLV 655
>gb|EAS02491.1| Glycosyl hydrolases family 38 protein [Tetrahymena thermophila SB210]
Length = 996
Score = 129 bits (324), Expect(2) = 1e-31
Identities = 97/296 (32%), Positives = 149/296 (50%), Gaps = 15/296 (5%)
Frame = +3
Query: 363 IRLPGVYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIR 542
+R +Y +K E E + I VDDG GKEV I TN ++ F+TDS+G + +R
Sbjct: 668 LRFSSIYPQKQVCEVETFIHSIDVDDGIGKEVVMLINTNYKNDRKFFTDSNGLELQQRQI 727
Query: 543 DYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLV--DRSIGGSSIKDGQIELMLHR 716
+YR+ W + P++GNYYP+ I +ED + VLV DRS GG+S+ +G+IE+M+HR
Sbjct: 728 NYRNTWVLNQTDPVSGNYYPIGAIIGLEDTQTKQRVLVVNDRSQGGTSLNEGEIEIMIHR 787
Query: 717 RLLHDDGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLL 896
R L DD KGV+E+LNE + K +GL + ++Y+ + + E G+ I + L
Sbjct: 788 RTLKDDDKGVSESLNEFDDI-KPKQGLQQKVRHYIIFEKEKEST------GRLIQNHL-- 838
Query: 897 AFTEQDGGNW---ANSHVAKFSAMDSTYSLPDNVAMLT---------LQELEDGSVL-LR 1037
D N + + KF +L +N +++ L++ ED L L
Sbjct: 839 -----DSANQIFISKTSKKKFQLSQDFNNLFENSPLVSNKNPYLRVYLKQFEDYYTLRLY 893
Query: 1038 FAHLYEAGEDKDLSSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKA 1205
H +E E K S +D E +L+ANQ + AM + + KWKA
Sbjct: 894 NIHDFENAEFKLDSKFQILD--------------ELTLTANQSKQAMLQNKYKWKA 935
Score = 32.7 bits (73), Expect(2) = 1e-31
Identities = 20/63 (31%), Positives = 32/63 (50%)
Frame = +2
Query: 149 SDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPIL 328
S +K Q++F+ +Y +Y+ Q SGAY+FRP T + S TV +G ++
Sbjct: 598 SKTKKSFQSSFQIQYNFYMSST---EVHQPSGAYVFRPAQTPNMPYSEIKSATVYQGEVV 654
Query: 329 DEV 337
V
Sbjct: 655 TVV 657
>gb|EAS02490.1| Glycosyl hydrolases family 38 protein [Tetrahymena thermophila SB210]
Length = 996
Score = 126 bits (316), Expect(2) = 1e-30
Identities = 86/283 (30%), Positives = 146/283 (51%), Gaps = 2/283 (0%)
Frame = +3
Query: 363 IRLPGVYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIR 542
+R +Y++K E E + I V+DG GKEV I TN + F+TDS+G + +R
Sbjct: 659 LRFSSIYQQKQACEVETFIHSIDVNDGVGKEVVMLINTNYKNDGKFFTDSNGLELQQRQV 718
Query: 543 DYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLV--DRSIGGSSIKDGQIELMLHR 716
++R+ W ++ +P++GNYYP+ I +ED + VLV DRS GG+S+ GQIE+M+HR
Sbjct: 719 NFRNTWDLKQTEPVSGNYYPIGAIIGLEDQETKQRVLVVNDRSQGGTSLNQGQIEIMIHR 778
Query: 717 RLLHDDGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLL 896
R+L DDG+GVAE+LNE + Q +GL + ++Y+ + + E + + +
Sbjct: 779 RILRDDGRGVAESLNEFDDIKAQ-QGLQQKVRHYIVFEKEKESTGRLIQNNLDSAHQIFI 837
Query: 897 AFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDL 1076
+ T Q+ F + +L +N ++ + L +F Y ++
Sbjct: 838 SKTSQN----------LFQLSQNFSNLFENSPFVSNKNPYLRVYLKQFPDYYTL-RLYNI 886
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKA 1205
+ + K + K + E +L+ANQ + M + + KWKA
Sbjct: 887 HDFVNAEFKL---DSKFKILDELTLTANQSKQTMLQNKYKWKA 926
Score = 32.3 bits (72), Expect(2) = 1e-30
Identities = 17/40 (42%), Positives = 22/40 (55%)
Frame = +2
Query: 146 YSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRPN 265
Y S + +F+ +Y YY N Q+SGAYIFRPN
Sbjct: 582 YIRSYRLFSNSFQIQYNYYTSSTDNY---QSSGAYIFRPN 618
>ref|XP_822510.1| lysosomal alpha-mannosidase precursor [Trypanosoma brucei TREU927]
gb|EAN77682.1| lysosomal alpha-mannosidase precursor, putative [Trypanosoma brucei]
Length = 997
Score = 129 bits (323), Expect(2) = 2e-30
Identities = 87/276 (31%), Positives = 144/276 (52%), Gaps = 20/276 (7%)
Frame = +3
Query: 393 DFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEV 572
D ++ EF IPV DG G+E+ T++ + FYTDS+GR+ +R D R +
Sbjct: 692 DTVDLEFTSLGIPVKDGFGRELVARFSTSVNNSGIFYTDSNGREMQRREVDKRRNYPFVQ 751
Query: 573 HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
+ +AGNYYPV+ I++ D + +V D ++GG+SI +G++ L HRRLL DD KGV+E
Sbjct: 752 TESVAGNYYPVSSLIFINDTETQFNVFTDAAMGGTSINNGEVLLTTHRRLLLDDQKGVSE 811
Query: 753 ALNET---------VCLDKQCEG------LIIQGKYYVKIDPQGEGA--RWRRTFGQEIY 881
LNET ++++ G L ++G + + G A R R ++ +
Sbjct: 812 PLNETEFITAYEGDPSMNEKGRGKHYGNPLRVRGTLTISVGRSGPSAMRRVREQLDEKYF 871
Query: 882 SPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAG 1061
SP+ + T G+ N + +++ T P +V ++T Q L ++LLR AH Y G
Sbjct: 872 SPIAVYST----GSTPNLN----CSLELTQISP-SVQIITTQLLNKTTLLLRIAHRYAVG 922
Query: 1062 EDKDLSSLASIDLKRVFPEK---KIGKVIETSLSAN 1160
ED + S ++L+ + P + + + E SL+ N
Sbjct: 923 EDDERSKSVEVELRSLIPNELDYNVESIDEVSLTTN 958
Score = 28.9 bits (63), Expect(2) = 2e-30
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
Frame = +2
Query: 104 NLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP---NGTV 274
+LK+++ G+L + E + Y+ G + GAYI RP N
Sbjct: 597 HLKVRFGVNGRLKSIEVLSVGQEVLVEHDWCYFKSSRGEDPSGISGGAYIMRPVSDNVCE 656
Query: 275 PISTDGQVSLTV 310
PISTD S+ +
Sbjct: 657 PISTDKVESIII 668
>gb|EAR94069.1| Glycosyl hydrolases family 38 protein [Tetrahymena thermophila SB210]
Length = 980
Score = 129 bits (324), Expect = 4e-28
Identities = 90/277 (32%), Positives = 145/277 (52%), Gaps = 4/277 (1%)
Frame = +3
Query: 390 KDFLETEFIVGPIPV-DDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKI 566
K+ +E E + IPV D GKEV I T + N+TFYTDS+G + KRI +YR W++
Sbjct: 695 KNIVEIETFIDGIPVLKDLRGKEVVLLIKTEISNNQTFYTDSNGLELQKRILNYRPTWQL 754
Query: 567 EVHQPIAGNYYPVNLGIYVED--GSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGK 740
+VH+ ++GNYYP+N I ++D K +SV+ DRS G SS+ +G+IE+M+HRRLL+DD +
Sbjct: 755 KVHEKVSGNYYPINGMIVIKDVNNGKRVSVINDRSQGASSLHEGEIEVMIHRRLLNDDYR 814
Query: 741 GVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAF-TEQDG 917
GV E LNE + K GL + ++Y+ + +G+ RR Q + L + F E
Sbjct: 815 GVTEPLNE-LEPGKLDSGLTQKVRHYLVFE-EGDETLSRRV--QSYHDSLPIIFQAESKS 870
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
+ S + + + S D + Q + +L +++L ++
Sbjct: 871 NTFEKSQIPQ--TFNPLMSNSDPFLKVVFQPYGENYIL-------------RVTNLNDVN 915
Query: 1098 LKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQ 1208
+ I + E +L+ANQ + M K + KW +
Sbjct: 916 STNYSIPEGIEMIEEVTLTANQNKEQMLKDKFKWNIE 952
>gb|EAS04708.1| Glycosyl hydrolases family 38 protein [Tetrahymena thermophila SB210]
Length = 1220
Score = 128 bits (322), Expect = 6e-28
Identities = 83/270 (30%), Positives = 148/270 (54%), Gaps = 3/270 (1%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E V PI V + GKE+ + T + NKTFYTDS+G D KR+ ++R W +++ Q
Sbjct: 632 IEVETFVHPIQVQN-TGKEIIMVLNTGLQNNKTFYTDSNGLDMQKRVLNFRPTWNLQLQQ 690
Query: 579 PIAGNYYPVNLGIYVED--GSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
++GNYYP+ I ++D +++SV+ DRS GG+S+K+GQIE+M+HRR++ DD +GV E
Sbjct: 691 EVSGNYYPIGALISLKDINSDQQVSVVTDRSQGGTSLKEGQIEIMIHRRIVRDDARGVGE 750
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWAN 932
+LNE +D++ +G+ + ++++ + Q E RR + SPL+
Sbjct: 751 SLNE---VDQRNQGISQKIRHFIIFERQNEQLS-RRIQNELDASPLIF------------ 794
Query: 933 SHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLR-FAHLYEAGEDKDLSSLASIDLKRV 1109
FS + Y + + + +E+ ++ LR + Y+ L ++ I +
Sbjct: 795 -----FSQTKNQYFDYRSNSQNRNKIIENQNIYLRVYLRAYKNYYTLRLYNVNDISSAQF 849
Query: 1110 FPEKKIGKVIETSLSANQERAAMEKKRLKW 1199
+ + E +L+ANQ + + +K++KW
Sbjct: 850 DIPQNYQILEELTLTANQSKKSWSEKQMKW 879
>gb|AAA81731.2| Hypothetical protein F55D10.1 [Caenorhabditis elegans]
ref|NP_508811.1| F55D10.1 [Caenorhabditis elegans]
Length = 955
Score = 121 bits (304), Expect = 7e-26
Identities = 86/269 (31%), Positives = 138/269 (51%), Gaps = 2/269 (0%)
Frame = +3
Query: 363 IRLPGVYKEKDFLETEFIVGPIPVDDGNG--KEVATEIVTNMVTNKTFYTDSSGRDFIKR 536
IRLP + K+++E E+IVGPIP + N KE T T + + +TDS+GR ++R
Sbjct: 666 IRLP---RGKNYIEFEWIVGPIPKETKNPITKEFVTRYTTEVHSKNQSFTDSNGRQAMER 722
Query: 537 IRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHR 716
D + ++ +PIAGNYYP+ Y++D + + SV+ DR+ G DG +E+MLHR
Sbjct: 723 FFDGATSFEYSDTEPIAGNYYPITSFGYIKDENAQFSVITDRA-QGMVASDGVVEIMLHR 781
Query: 717 RLLHDDGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLL 896
R +DD GV EAL+E K GL+ GK+ V R + + +L
Sbjct: 782 RCFYDDHFGVEEALDEP---GKDGAGLVAMGKHIVLFTDVKASTSQLRPLAIDNFHQPVL 838
Query: 897 AFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDL 1076
AF ++ + + + ++S + + LP + +LTL++ S L+RF ++Y E
Sbjct: 839 AF-NKNPEKFEFNRLLEYSGL--KFELPIGIHLLTLEKWHKKSSLIRFENIYHGEEG--- 892
Query: 1077 SSLASIDLKRVFPEKKIGKVIETSLSANQ 1163
+S+ D +F I E L AN+
Sbjct: 893 NSIKEFDPTHIFTNFDIVSFKELLLGANR 921
Score = 60.1 bits (144), Expect = 3e-07
Identities = 33/105 (31%), Positives = 60/105 (57%)
Frame = +2
Query: 77 SSNLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIF 256
++N+++ L ++ G LS ++ T + + Q++ YY G D D Q SGAYIF
Sbjct: 570 NTNVEIQNEYLIAGFDSQGYLSYITEKATKKKRSIRQEFFYYEGIDSK--DDQPSGAYIF 627
Query: 257 RPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRRLQGE 391
RP PI+ +++L V+ G I++EV Q+++ ++ Q R +G+
Sbjct: 628 RPKTQQPIALTSKLALEVVPGAIINEVRQKVSPFVSQQIRLPRGK 672
>gb|AAX26929.2| SJCHGC06403 protein [Schistosoma japonicum]
Length = 354
Score = 110 bits (275), Expect = 2e-22
Identities = 101/347 (29%), Positives = 167/347 (48%), Gaps = 41/347 (11%)
Frame = +3
Query: 399 LETEFIVGPIPVDDG--NGKEVATEIVTN----MVTNK-TFYTDSSGRDFIKRIRDYRSE 557
LE E+ GPIP DDG N +E+ N + N F+TDSSGR I+R+R+ R +
Sbjct: 11 LEVEWTAGPIP-DDGYTNSRELVIRYTVNNTNIFIKNPGEFFTDSSGRRMIRRLRNKRID 69
Query: 558 WKIEVH----QPIAGNYYPVNLGIYVED----GSKE-----------LSVLVDRSIGGSS 680
W + ++ + IAGNYYPV I +++ S E L++ DR+ GG+S
Sbjct: 70 WNLPINFTETENIAGNYYPVVNRIMLKNIILHKSNENPLEDEGVPLGLAIYTDRAHGGTS 129
Query: 681 IKDGQIELMLHRRLLHDDGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR 860
+ DGQIELMLHRRL+ DDG GV+E L E LD + GLI++G + ++ D R
Sbjct: 130 LHDGQIELMLHRRLVRDDGFGVSEPLMEN-GLDGR--GLIVRGIHKIRFDELDYIELEDR 186
Query: 861 TFGQEIYSPLLLAF---------TEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQEL 1013
Q + P++ F + +G + N + + S S P N L+
Sbjct: 187 RIAQLVSRPIIPLFMHAKHQPKSMQVNGWSGLNIGLPNHIHLLSLTSWPLNKVYLS-NSR 245
Query: 1014 EDGSVLLRFAHLYEAGEDKDLSSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRL 1193
E +L+R +L + + +ID+ + KI + E L+A+Q + RL
Sbjct: 246 ESNQILIRLENLQSSNSLTSIKP-CTIDITYLINGIKIIGMKEMILTADQLKTTSLLHRL 304
Query: 1194 KWKAQGSAADEKVV------RGGPVDPSKLVVELGPMEIRTFIVSFD 1316
W + ++D + ++ + +++ + P +I T+I+ ++
Sbjct: 305 NWPTELPSSDNYTLYTKHKCNADNLNSNGVLLTIEPGKIVTYILDYE 351
>gb|AAC72969.1| lysosomal alpha mannosidase [Trypanosoma cruzi]
Length = 393
Score = 100 bits (249), Expect = 2e-19
Identities = 78/289 (26%), Positives = 134/289 (46%), Gaps = 24/289 (8%)
Frame = +3
Query: 393 DFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEV 572
D ++ EF IP+ D G+E+ T++ + FYTDS+GR+ +R D+RS++
Sbjct: 95 DLVDVEFTSFGIPIHDNFGRELVARFRTSVESGDVFYTDSNGREMQRRRVDHRSDYPFTQ 154
Query: 573 HQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE 752
+P+AGN+YPV +V D + +V D +GG+S++ G++ L +GV
Sbjct: 155 TEPVAGNFYPVTSVFFVHDTQTQFNVFPDAPMGGTSLQSGEVLLWFTDVFYVTTLEGVEN 214
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDP------------------QGEGARWRRTFGQEI 878
L + L + + Q + V I P Q R R +
Sbjct: 215 LLTKPP-LSQATRIVGCQRQVIVAIIPPLPCVFAARCHFQCRGVAQPRMRRVRDPQDENY 273
Query: 879 YSPLLLAFTEQDGGNWANSHVAKFSAMDST---YSLPDNVAMLTLQELEDGSVLLRFAHL 1049
Y+PL++ + +++ A A ++T +SLP ++ ++TLQ ++ +LLR H
Sbjct: 274 YTPLVMFSS-------SSTDAASAIARNNTSFGFSLPPSLQVVTLQLIDQQKLLLRLGHR 326
Query: 1050 YEAGEDKDLSSLASIDLKRVFPE---KKIGKVIETSLSANQERAAMEKK 1187
Y ED + S +DL +F E I + E SL+A + A + K
Sbjct: 327 YAVSEDPERSLPVEVDLMTIFREFHWITILSIDEVSLTAVGDSATPDPK 375
>ref|XP_420805.1| PREDICTED: similar to hypothetical protein [Gallus gallus]
Length = 1101
Score = 97.4 bits (241), Expect = 2e-18
Identities = 92/337 (27%), Positives = 152/337 (45%), Gaps = 32/337 (9%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ +GP+ V+ +E TN+ T + YTD +G KR +K V+
Sbjct: 788 IEQEYSIGPLEVN----REAVLRTSTNLNTGQLLYTDDNGFQIQKR------PFKAYVNN 837
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
A NYYP+ Y+ED + L +L +R+ G SS +GQ+E+MLHRRL ++ + L
Sbjct: 838 TAARNYYPMVQTAYIEDDTTRLVLLAERAHGVSSQGNGQVEVMLHRRLWNN----LQWDL 893
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEI-YSPLLLAFTEQDGGNWANS 935
N + L+ + +++ +++ + + + RT G + + P+++ T
Sbjct: 894 NYNLTLN---DSSVVRPVFWLILGTKSATSVLYRTSGLALQHRPVVMFGTFSGDKPELPG 950
Query: 936 HVAKFSAMDSTYSLPDNVAMLTLQ-------------------------ELEDGSVLLRF 1040
+ K SA + ++P N+ + TL + + VLLR
Sbjct: 951 QLQKRSAHSFSVTVPPNLHLQTLSIPGWRYSSNHAEQVRAIHMGKQKQGDADFSRVLLRI 1010
Query: 1041 AHLYEAGEDKDLSSLASIDLKRVFPEKKIGKVI-ETSLSANQERAAMEKKRLKWK----- 1202
HLYE GED LS ++LK + E K++ E SL+ + + KR KWK
Sbjct: 1011 RHLYEVGEDPVLSQPVMVNLKSLLKELGSVKLVEERSLTGTWDVNTL--KRWKWKTVQNR 1068
Query: 1203 AQGSAADEKVVRGGPVDPSKLVVELGPMEIRTFIVSF 1313
+QG + K+ V + P EIRTF V F
Sbjct: 1069 SQGFSNSTKI-------SDDFTVTVHPKEIRTFFVYF 1098
>gb|EAA13579.3| ENSANGP00000014255 [Anopheles gambiae str. PEST]
ref|XP_318477.2| ENSANGP00000014255 [Anopheles gambiae str. PEST]
Length = 761
Score = 74.3 bits (181), Expect(2) = 7e-15
Identities = 37/113 (32%), Positives = 63/113 (55%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPV 605
+ + + E+ + TN+ + TFYTD +G IKR R + PI NYYPV
Sbjct: 657 VDIGQRDNTEIVMRLQTNINSGATFYTDLNGMQIIKRKRFQKL--------PIQANYYPV 708
Query: 606 NLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+++ED + L++L + +GGSS+ G++E+M RRL DD +G+ + + +
Sbjct: 709 PSTMFIEDDNYRLTLLGGQPLGGSSLSSGEMEIMQDRRLTRDDDRGLGQGVQD 761
Score = 31.2 bits (69), Expect(2) = 7e-15
Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 8/81 (9%)
Frame = +2
Query: 107 LKLQYNEAGKLSLYSDSKTMV--------QANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+ L++ E G S SK ++ QA ++Y + G SGAY+F P
Sbjct: 551 MSLRFEEGGSTSAAFTSKGLLKSLTIENNQATVPVHLEFY--RYGMQLSSGKSGAYLFHP 608
Query: 263 NGTVPISTDGQVSLTVLRGPI 325
G + T Q + V++GP+
Sbjct: 609 AGNATLMTYDQPIVLVMKGPL 629
>ref|NP_524291.2| Mannosidase II CG18802-PA [Drosophila melanogaster]
gb|AAM50118.1| GH03876p [Drosophila melanogaster]
gb|AAF54375.1| CG18802-PA [Drosophila melanogaster]
sp|Q24451|MAN2_DROME Alpha-mannosidase II (Mannosyl-oligosaccharide
1,3-1,6-alpha-mannosidase) (MAN II) (Golgi
alpha-mannosidase II) (AMAN II)
Length = 1108
Score = 72.4 bits (176), Expect(2) = 2e-14
Identities = 35/102 (34%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++ED
Sbjct: 852 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGMFIEDA 903
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 904 NTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGV 945
Score = 31.6 bits (70), Expect(2) = 2e-14
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 740 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 794
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 795 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 833
>emb|CAA54732.1| putative golgi alpha-mannosidase II [Drosophila melanogaster]
Length = 1108
Score = 72.4 bits (176), Expect(2) = 2e-14
Identities = 35/102 (34%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++ED
Sbjct: 852 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGMFIEDA 903
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 904 NTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGV 945
Score = 31.6 bits (70), Expect(2) = 2e-14
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 740 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 794
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 795 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 833
>emb|CAA10755.1| alpha-mannosidase II [Drosophila melanogaster]
Length = 1108
Score = 72.4 bits (176), Expect(2) = 2e-14
Identities = 35/102 (34%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++ED
Sbjct: 852 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGMFIEDA 903
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 904 NTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGV 945
Score = 31.6 bits (70), Expect(2) = 2e-14
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 740 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 794
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 795 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 833
>pdb|1R34|A Chain A, Golgi Alpha-Mannosidase Ii Complex With 5-Thio-D-
Mannopyranosylamidinium Salt
pdb|1R33|A Chain A, Golgi Alpha-Mannosidase Ii Complex With 5-Thio-D-
Mannopyranosylamine
pdb|1TQW|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With A Diastereomer Of
Seleno-Salacinol
pdb|1TQV|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With Seleno-Salacinol
(Blintol)
pdb|1TQU|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With The Salacinol
Analog Ghavamiol
pdb|1TQT|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With A Diastereomer Of
Salacinol
pdb|1TQS|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With Salacinol
pdb|1QWN|A Chain A, Golgi Alpha-Mannosidase Ii Covalent Intermediate Complex
With 5-Fluoro-Gulosyl-Fluoride
Length = 1045
Score = 72.4 bits (176), Expect(2) = 2e-14
Identities = 35/102 (34%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++ED
Sbjct: 789 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGMFIEDA 840
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 841 NTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGV 882
Score = 31.6 bits (70), Expect(2) = 2e-14
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 677 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 731
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 732 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 770
>pdb|1QX1|A Chain A, Golgi Alpha-Mannosidase Ii D341n Mutant Complex With 2-F-
Mannosyl-F
pdb|1QWU|A Chain A, Golgi Alpha-Mannosidase Ii D341n Mutant Complex With 5-F-
Guloside
Length = 1045
Score = 72.4 bits (176), Expect(2) = 2e-14
Identities = 35/102 (34%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++ED
Sbjct: 789 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGMFIEDA 840
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 841 NTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGV 882
Score = 31.6 bits (70), Expect(2) = 2e-14
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 677 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 731
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 732 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 770
>pdb|1PS3|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With Kifunensine
Length = 1045
Score = 72.4 bits (176), Expect(2) = 2e-14
Identities = 35/102 (34%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++ED
Sbjct: 789 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGMFIEDA 840
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 841 NTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGV 882
Score = 31.6 bits (70), Expect(2) = 2e-14
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 677 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 731
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 732 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 770
>pdb|1HWW|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With Swainsonine
pdb|1HXK|A Chain A, Golgi Alpha-Mannosidase Ii In Complex With
Deoxymannojirimicin
Length = 1015
Score = 72.4 bits (176), Expect(2) = 2e-14
Identities = 35/102 (34%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++ED
Sbjct: 759 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGMFIEDA 810
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 811 NTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGV 852
Score = 31.6 bits (70), Expect(2) = 2e-14
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 647 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 701
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 702 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 740
>ref|NP_032576.1| mannosidase alpha class 2B member 2 [Mus musculus]
dbj|BAA24266.1| alpha-D-mannosidase [Mus musculus]
Length = 1018
Score = 82.8 bits (203), Expect = 4e-14
Identities = 87/333 (26%), Positives = 147/333 (44%), Gaps = 28/333 (8%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E ++ VGP+ ++ +E +++ + + Y+D++G +R +K
Sbjct: 710 IEQQYRVGPLDLN----REAILRTSSDLNSQQVLYSDNNGYQMQRR------PYKAFKSN 759
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
PI NYYP+ ++ED L +L +R G SS +GQ+E+MLHRRL ++ +A L
Sbjct: 760 PIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNN----LAWDL 815
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEI-YSPLLLAFTEQD------- 914
+ L+ + I+ ++ + P+ G + + P++L D
Sbjct: 816 KYNLTLN---DTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKELADEETPVHG 872
Query: 915 -GGNW-----ANSHVAKFSAMDSTYSLPDNVAMLTLQ-------ELEDGSVLLRFAHLYE 1055
W N H+ S TYS + LQ + VLLR HLYE
Sbjct: 873 PHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYE 932
Query: 1056 AGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKAQGSAADE 1226
AGED LS A++DLK V + +G V+ E SL+ + ++ R W +
Sbjct: 933 AGEDPVLSRPATVDLKVVL--RGLGSVVAVEERSLTGTWDVQMLQ--RWHWSTKTDH--- 985
Query: 1227 KVVRGGPVDPSK----LVVELGPMEIRTFIVSF 1313
++G P P + ++ + P EIRTF + F
Sbjct: 986 --LKGHPTSPPRPPGGSIITVYPKEIRTFFIKF 1016
>dbj|BAE38153.1| unnamed protein product [Mus musculus]
Length = 1018
Score = 82.8 bits (203), Expect = 4e-14
Identities = 87/333 (26%), Positives = 147/333 (44%), Gaps = 28/333 (8%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E ++ VGP+ ++ +E +++ + + Y+D++G +R +K
Sbjct: 710 IEQQYRVGPLDLN----REAILRTSSDLNSQQVLYSDNNGYQMQRR------PYKAFKSN 759
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
PI NYYP+ ++ED L +L +R G SS +GQ+E+MLHRRL ++ +A L
Sbjct: 760 PIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNN----LAWDL 815
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEI-YSPLLLAFTEQD------- 914
+ L+ + I+ ++ + P+ G + + P++L D
Sbjct: 816 KYNLTLN---DTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKELADEETPVHG 872
Query: 915 -GGNW-----ANSHVAKFSAMDSTYSLPDNVAMLTLQ-------ELEDGSVLLRFAHLYE 1055
W N H+ S TYS + LQ + VLLR HLYE
Sbjct: 873 PHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYE 932
Query: 1056 AGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKAQGSAADE 1226
AGED LS A++DLK V + +G V+ E SL+ + ++ R W +
Sbjct: 933 AGEDPVLSRPATVDLKVVL--RGLGSVVAVEERSLTGTWDVQMLQ--RWHWSTKTDH--- 985
Query: 1227 KVVRGGPVDPSK----LVVELGPMEIRTFIVSF 1313
++G P P + ++ + P EIRTF + F
Sbjct: 986 --LKGHPTSPPRPPGGSIITVYPKEIRTFFIKF 1016
>dbj|BAC30580.1| unnamed protein product [Mus musculus]
gb|AAH66211.1| Mannosidase alpha class 2B member 2 [Mus musculus]
dbj|BAC53862.1| homologue of the porcine 135kDa a-D-mannosidase [Mus musculus]
sp|O54782|MA2B2_MOUSE Epididymis-specific alpha-mannosidase precursor (Mannosidase alpha
class 2B member 2)
Length = 1018
Score = 82.8 bits (203), Expect = 4e-14
Identities = 87/333 (26%), Positives = 147/333 (44%), Gaps = 28/333 (8%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E ++ VGP+ ++ +E +++ + + Y+D++G +R +K
Sbjct: 710 IEQQYRVGPLDLN----REAILRTSSDLNSQQVLYSDNNGYQMQRR------PYKAFKSN 759
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
PI NYYP+ ++ED L +L +R G SS +GQ+E+MLHRRL ++ +A L
Sbjct: 760 PIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNN----LAWDL 815
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEI-YSPLLLAFTEQD------- 914
+ L+ + I+ ++ + P+ G + + P++L D
Sbjct: 816 KYNLTLN---DTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKELADEETPVHG 872
Query: 915 -GGNW-----ANSHVAKFSAMDSTYSLPDNVAMLTLQ-------ELEDGSVLLRFAHLYE 1055
W N H+ S TYS + LQ + VLLR HLYE
Sbjct: 873 PHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYE 932
Query: 1056 AGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKAQGSAADE 1226
AGED LS A++DLK V + +G V+ E SL+ + ++ R W +
Sbjct: 933 AGEDPVLSRPATVDLKVVL--RGLGSVVAVEERSLTGTWDVQMLQ--RWHWSTKTDH--- 985
Query: 1227 KVVRGGPVDPSK----LVVELGPMEIRTFIVSF 1313
++G P P + ++ + P EIRTF + F
Sbjct: 986 --LKGHPTSPPRPPGGSIITVYPKEIRTFFIKF 1016
>dbj|BAB23655.1| unnamed protein product [Mus musculus]
Length = 1018
Score = 82.8 bits (203), Expect = 4e-14
Identities = 87/333 (26%), Positives = 147/333 (44%), Gaps = 28/333 (8%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E ++ VGP+ ++ +E +++ + + Y+D++G +R +K
Sbjct: 710 IEQQYRVGPLDLN----REAILRTSSDLNSQQVLYSDNNGYQMQRR------PYKAFKSN 759
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
PI NYYP+ ++ED L +L +R G SS +GQ+E+MLHRRL ++ +A L
Sbjct: 760 PIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNN----LAWDL 815
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEI-YSPLLLAFTEQD------- 914
+ L+ + I+ ++ + P+ G + + P++L D
Sbjct: 816 KYNLTLN---DTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKELADEETPVHG 872
Query: 915 -GGNW-----ANSHVAKFSAMDSTYSLPDNVAMLTLQ-------ELEDGSVLLRFAHLYE 1055
W N H+ S TYS + LQ + VLLR HLYE
Sbjct: 873 PHNPWPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYE 932
Query: 1056 AGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKAQGSAADE 1226
AGED LS A++DLK V + +G V+ E SL+ + ++ R W +
Sbjct: 933 AGEDPVLSRPATVDLKVVL--RGLGSVVAVEERSLTGTWDVQMLQ--RWHWSTKTDH--- 985
Query: 1227 KVVRGGPVDPSK----LVVELGPMEIRTFIVSF 1313
++G P P + ++ + P EIRTF + F
Sbjct: 986 --LKGHPTSPPRPPGGSIITVYPKEIRTFFIKF 1016
>ref|XP_610717.2| PREDICTED: similar to Epididymis-specific alpha-mannosidase precursor
(Mannosidase alpha class 2B member 2), partial [Bos
taurus]
Length = 783
Score = 82.0 bits (201), Expect = 7e-14
Identities = 88/343 (25%), Positives = 151/343 (44%), Gaps = 38/343 (11%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKR-IRDYRSEWKIEVH 575
+E E+ VGP+ ++ +E T + T + Y+D++G +R R+Y++
Sbjct: 473 IEQEYRVGPLELN----REAILRTSTKLNTGRVLYSDNNGYQMQRRPYRNYKNN------ 522
Query: 576 QPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEA 755
IA NYYP+ +++D L +L +++ G SS ++GQ+E+MLHRRL ++D A
Sbjct: 523 -TIARNYYPMVQSAFIQDRRSRLVLLSNQAHGVSSQRNGQVEVMLHRRLWNND----KWA 577
Query: 756 LNETVCLD----------------------KQCEGLIIQGKYYV------KIDPQGEGAR 851
LN + L+ Q GL +Q + V +I P+G G+R
Sbjct: 578 LNNDLTLNDSSVVHPVLWLLLGSRTLTSDLHQRSGLALQHQPVVMLREMNEIAPRGSGSR 637
Query: 852 WRRTFGQEIYSPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVL 1031
+ + + L G ++++H + + + A L VL
Sbjct: 638 QQEAV--TLPPSVHLQILSIPGWKYSSNHTEHLQTLQKGAAGHEAKADLR-------RVL 688
Query: 1032 LRFAHLYEAGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWK 1202
LR HLYE +D LS +++L+ V + +G V+ E SL+ + E +R W
Sbjct: 689 LRLQHLYEVDQDPVLSRPVTVNLQSVL--RGLGSVVSVEERSLTGTWD--VSEMRRWTWS 744
Query: 1203 A------QGSAADEKVVRGGPVDPSKLVVELGPMEIRTFIVSF 1313
+G+++ GGP V + P EIRTF + F
Sbjct: 745 MRDPHGHRGNSSRPSPPPGGP------EVTIYPKEIRTFFIHF 781
>gb|AAH94773.1| Mannosidase, alpha, class 2B, member 2 [Homo sapiens]
Length = 1009
Score = 81.3 bits (199), Expect = 1e-13
Identities = 89/327 (27%), Positives = 142/327 (43%), Gaps = 22/327 (6%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ GP+ ++ +E TN+ + + Y+D++G +R + V+
Sbjct: 700 IEQEYQAGPLELN----REAVLRTSTNLNSQQVIYSDNNGYQMQRR------PYVSYVNN 749
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAE 752
IA NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G
Sbjct: 750 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 809
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGG 920
LN+T + L+ + + A R FG +P L +Q+
Sbjct: 810 TLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAV 869
Query: 921 NW-ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDL 1076
N H+ S YS L++ G VLLR HLYE GED L
Sbjct: 870 TLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVL 929
Query: 1077 SSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKA-----QGSAADEKV 1232
S +++L+ V + +G V+ E SL+ + + + R W+ +G
Sbjct: 930 SQPVTVNLEAVL--QALGSVVAVEERSLTGTWDLSMLH--RWSWRTGPGRHRGDTTSPSR 985
Query: 1233 VRGGPVDPSKLVVELGPMEIRTFIVSF 1313
GGP ++ + P EIRTF + F
Sbjct: 986 PPGGP------IITVHPKEIRTFFIHF 1006
>ref|NP_056089.1| mannosidase, alpha, class 2B, member 2 [Homo sapiens]
Length = 1009
Score = 81.3 bits (199), Expect = 1e-13
Identities = 89/327 (27%), Positives = 142/327 (43%), Gaps = 22/327 (6%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ GP+ ++ +E TN+ + + Y+D++G +R + V+
Sbjct: 700 IEQEYQAGPLELN----REAVLRTSTNLNSQQVIYSDNNGYQMQRR------PYVSYVNN 749
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAE 752
IA NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G
Sbjct: 750 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 809
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGG 920
LN+T + L+ + + A R FG +P L +Q+
Sbjct: 810 TLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAV 869
Query: 921 NW-ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDL 1076
N H+ S YS L++ G VLLR HLYE GED L
Sbjct: 870 TLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVL 929
Query: 1077 SSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKA-----QGSAADEKV 1232
S +++L+ V + +G V+ E SL+ + + + R W+ +G
Sbjct: 930 SQPVTVNLEAVL--QALGSVVAVEERSLTGTWDLSMLH--RWSWRTGPGRHRGDTTSPSR 985
Query: 1233 VRGGPVDPSKLVVELGPMEIRTFIVSF 1313
GGP ++ + P EIRTF + F
Sbjct: 986 PPGGP------IITVHPKEIRTFFIHF 1006
>gb|AAH33307.1| Mannosidase, alpha, class 2B, member 2 [Homo sapiens]
Length = 1009
Score = 81.3 bits (199), Expect = 1e-13
Identities = 89/327 (27%), Positives = 142/327 (43%), Gaps = 22/327 (6%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ GP+ ++ +E TN+ + + Y+D++G +R + V+
Sbjct: 700 IEQEYQAGPLELN----REAVLRTSTNLNSQQVIYSDNNGYQMQRR------PYVSYVNN 749
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAE 752
IA NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G
Sbjct: 750 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 809
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGG 920
LN+T + L+ + + A R FG +P L +Q+
Sbjct: 810 TLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAV 869
Query: 921 NW-ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDL 1076
N H+ S YS L++ G VLLR HLYE GED L
Sbjct: 870 TLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVL 929
Query: 1077 SSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKA-----QGSAADEKV 1232
S +++L+ V + +G V+ E SL+ + + + R W+ +G
Sbjct: 930 SQPVTVNLEAVL--QALGSVVAVEERSLTGTWDLSMLH--RWSWRTGPGRHRGDTTSPSR 985
Query: 1233 VRGGPVDPSKLVVELGPMEIRTFIVSF 1313
GGP ++ + P EIRTF + F
Sbjct: 986 PPGGP------IITVHPKEIRTFFIHF 1006
>emb|CAD89971.1| hypothetical protein [Homo sapiens]
Length = 1009
Score = 81.3 bits (199), Expect = 1e-13
Identities = 89/327 (27%), Positives = 142/327 (43%), Gaps = 22/327 (6%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ GP+ ++ +E TN+ + + Y+D++G +R + V+
Sbjct: 700 IEQEYQAGPLELN----REAVLRTSTNLNSQQVIYSDNNGYQMQRR------PYVSYVNN 749
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAE 752
IA NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G
Sbjct: 750 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 809
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGG 920
LN+T + L+ + + A R FG +P L +Q+
Sbjct: 810 TLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAV 869
Query: 921 NW-ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDL 1076
N H+ S YS L++ G VLLR HLYE GED L
Sbjct: 870 TLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVL 929
Query: 1077 SSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKA-----QGSAADEKV 1232
S +++L+ V + +G V+ E SL+ + + + R W+ +G
Sbjct: 930 SQPVTVNLEAVL--QALGSVVAVEERSLTGTWDLSMLH--RWSWRTGPGRHRGDTTSPSR 985
Query: 1233 VRGGPVDPSKLVVELGPMEIRTFIVSF 1313
GGP ++ + P EIRTF + F
Sbjct: 986 PPGGP------IITVHPKEIRTFFIHF 1006
>emb|CAH90164.1| hypothetical protein [Pongo pygmaeus]
sp|Q5RDJ3|MA2B2_PONPY Epididymis-specific alpha-mannosidase precursor (Mannosidase alpha
class 2B member 2)
Length = 1009
Score = 81.3 bits (199), Expect = 1e-13
Identities = 89/327 (27%), Positives = 142/327 (43%), Gaps = 22/327 (6%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ GP+ ++ +E TN+ + + Y+D++G +R + V+
Sbjct: 700 IEQEYQAGPLELN----REAVLRTSTNLNSQQVIYSDNNGYQMQRR------PYVSYVNN 749
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAE 752
IA NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G
Sbjct: 750 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 809
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGG 920
LN+T + L+ + + A R FG +P L +Q+
Sbjct: 810 TLNDTSIVHPVLWLLLGSWSLTTALRQRSAMALQHRPVVLFGDLAGTAPKLPGPQQQEAV 869
Query: 921 NW-ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDL 1076
N H+ S YS L++ G VLLR HLYE GED L
Sbjct: 870 TLPPNLHLQILSIPGWRYSSNHTEHAQNLRKGNRGEVQADLHRVLLRLHHLYEVGEDPVL 929
Query: 1077 SSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKA-----QGSAADEKV 1232
S +++L+ V + +G V+ E SL+ + + + R W+ +G
Sbjct: 930 SQPVTVNLEAVL--QALGSVVAVEERSLTGTWDVSMLH--RWSWRTGSGRRRGDTTSPSR 985
Query: 1233 VRGGPVDPSKLVVELGPMEIRTFIVSF 1313
GGP ++ + P EIRTF + F
Sbjct: 986 PPGGP------IITVHPKEIRTFFIHF 1006
>sp|Q9Y2E5|MA2B2_HUMAN Epididymis-specific alpha-mannosidase precursor (Mannosidase alpha
class 2B member 2)
Length = 1009
Score = 81.3 bits (199), Expect = 1e-13
Identities = 89/327 (27%), Positives = 142/327 (43%), Gaps = 22/327 (6%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ GP+ ++ +E TN+ + + Y+D++G +R + V+
Sbjct: 700 IEQEYQAGPLELN----REAVLRTSTNLNSQQVIYSDNNGYQMQRR------PYVSYVNN 749
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAE 752
IA NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G
Sbjct: 750 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 809
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGG 920
LN+T + L+ + + A R FG +P L +Q+
Sbjct: 810 TLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAV 869
Query: 921 NW-ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDL 1076
N H+ S YS L++ G VLLR HLYE GED L
Sbjct: 870 TLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVL 929
Query: 1077 SSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKA-----QGSAADEKV 1232
S +++L+ V + +G V+ E SL+ + + + R W+ +G
Sbjct: 930 SQPVTVNLQAVL--QALGSVVAVEERSLTGTWDLSMLH--RWSWRTGPGRHRGDTTSPSR 985
Query: 1233 VRGGPVDPSKLVVELGPMEIRTFIVSF 1313
GGP ++ + P EIRTF + F
Sbjct: 986 PPGGP------IITVHPKEIRTFFIHF 1006
>pdb|1HTY|A Chain A, Golgi Alpha-Mannosidase Ii
Length = 1015
Score = 69.7 bits (169), Expect(2) = 1e-13
Identities = 34/102 (33%), Positives = 58/102 (56%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G ++ED
Sbjct: 759 EIVXRLETHIDSGDIFYTDLNGLQFIKRRRLDKL--------PLQANYYPIPSGXFIEDA 810
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+ RRL DD +G+ + +
Sbjct: 811 NTRLTLLTGQPLGGSSLASGELEIXQDRRLASDDERGLGQGV 852
Score = 31.6 bits (70), Expect(2) = 1e-13
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 647 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 701
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 702 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIXR 740
>gb|EAL26975.1| GA15085-PA [Drosophila pseudoobscura]
Length = 1101
Score = 72.0 bits (175), Expect(2) = 2e-13
Identities = 36/102 (35%), Positives = 60/102 (58%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G IKR R WK+ P+ NYYPV +++ED
Sbjct: 845 EIVMRLQTHIDSTNVFYTDLNGLQHIKR----RRLWKL----PLQANYYPVPSAMFIEDT 896
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ L++L + +GGSS+ G++E+M RRL DD +G+ + +
Sbjct: 897 NMRLTLLTGQPLGGSSLAAGEMEIMQDRRLARDDERGLGQGV 938
Score = 28.5 bits (62), Expect(2) = 2e-13
Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 9/98 (9%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L + K+ Y G SGAY+F P
Sbjct: 733 SLRVGNGPT-LAFSEYGLLKSMQLTPDSEHVPVHLKFLTY----GTREHGDRSGAYLFLP 787
Query: 263 NG---------TVPISTDGQVSLTVLRGPILDEVHQQI 349
NG V + T+G++ TV G + + +HQ I
Sbjct: 788 NGPATPYPELHDVVLVTEGKLESTVTVG-LRNVIHQTI 824
>sp|Q28949|MA2B2_PIG Epididymis-specific alpha-mannosidase precursor (Mannosidase alpha
class 2B member 2) (AMAN)
Length = 995
Score = 78.2 bits (191), Expect = 9e-13
Identities = 85/331 (25%), Positives = 147/331 (44%), Gaps = 26/331 (7%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ VGP+ ++ EV T++ T Y+D++G +R ++ + +
Sbjct: 685 IEQEYRVGPLELNH----EVVLRTSTSLNTGLVLYSDNNGYQMQRRT------YRHDRNN 734
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
++ NYYP+ +++DG L +L +++ G SS +GQ+E+MLHRRL + + L
Sbjct: 735 SVSLNYYPMAQSAFIQDGGSRLVLLSEQAHGVSSQGNGQVEVMLHRRLWNKLEWTLQYNL 794
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWANS- 935
V +++ ++ + P+ R+ G E+ ++ F E GG N
Sbjct: 795 THDVT-------SVVRPVLWLLLGPRTLTTGLRQRSGLELQHRPVVLFREL-GGTVQNGP 846
Query: 936 --------------HVAKFSAMDSTYSLPDNVAMLTLQ-------ELEDGSVLLRFAHLY 1052
H+ S YS V + LQ + + VLLR HLY
Sbjct: 847 GPRKQEPVTLPPSLHLQILSIPGWKYSSNHTVHLKNLQKGHYRRAKADFRRVLLRLHHLY 906
Query: 1053 EAGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKAQGSAAD 1223
EAGE + LS +++L+ V + +G V+ E SL+ + ++ R WK +
Sbjct: 907 EAGEHQALSRPVTLNLQSVL--RGLGSVVAVEERSLTGTWDVNSLH--RWSWKTEDGHHH 962
Query: 1224 EKVVRGGPVDPSK-LVVELGPMEIRTFIVSF 1313
R P+ P + V + P EIRTF + F
Sbjct: 963 RGSSR-RPLPPLRGPNVTIHPKEIRTFFIHF 992
>ref|NP_999014.1| 135kDa alpha-D-mannosidase [Sus scrofa]
pir||T42762 probable alpha-mannosidase (EC 3.2.1.24) - pig
dbj|BAA05877.1| 135kDa protein [Sus scrofa]
Length = 1006
Score = 78.2 bits (191), Expect = 9e-13
Identities = 85/331 (25%), Positives = 147/331 (44%), Gaps = 26/331 (7%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ VGP+ ++ EV T++ T Y+D++G +R ++ + +
Sbjct: 696 IEQEYRVGPLELNH----EVVLRTSTSLNTGLVLYSDNNGYQMQRRT------YRHDRNN 745
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
++ NYYP+ +++DG L +L +++ G SS +GQ+E+MLHRRL + + L
Sbjct: 746 SVSLNYYPMAQSAFIQDGGSRLVLLSEQAHGVSSQGNGQVEVMLHRRLWNKLEWTLQYNL 805
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWANS- 935
V +++ ++ + P+ R+ G E+ ++ F E GG N
Sbjct: 806 THDVT-------SVVRPVLWLLLGPRTLTTGLRQRSGLELQHRPVVLFREL-GGTVQNGP 857
Query: 936 --------------HVAKFSAMDSTYSLPDNVAMLTLQ-------ELEDGSVLLRFAHLY 1052
H+ S YS V + LQ + + VLLR HLY
Sbjct: 858 GPRKQEPVTLPPSLHLQILSIPGWKYSSNHTVHLKNLQKGHYRRAKADFRRVLLRLHHLY 917
Query: 1053 EAGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKAQGSAAD 1223
EAGE + LS +++L+ V + +G V+ E SL+ + ++ R WK +
Sbjct: 918 EAGEHQALSRPVTLNLQSVL--RGLGSVVAVEERSLTGTWDVNSLH--RWSWKTEDGHHH 973
Query: 1224 EKVVRGGPVDPSK-LVVELGPMEIRTFIVSF 1313
R P+ P + V + P EIRTF + F
Sbjct: 974 RGSSR-RPLPPLRGPNVTIHPKEIRTFFIHF 1003
>emb|CAG03449.1| unnamed protein product [Tetraodon nigroviridis]
Length = 1152
Score = 69.7 bits (169), Expect(2) = 2e-12
Identities = 35/113 (30%), Positives = 67/113 (59%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPV 605
+ + D N KE++ +VTN+ + FYTD + +I+ R K+ P+ N+YP+
Sbjct: 875 VDIRDQNNKELSMRLVTNIQSGDVFYTDHNAF----QIQPCRHFMKL----PLQANFYPM 926
Query: 606 NLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
Y++D + L++ +++G SS++ GQ+E++L RRL+ DD +G+ + L +
Sbjct: 927 PSQAYIQDSNYRLTLHTAQALGVSSLETGQLEVILDRRLMQDDNRGLGQGLKD 979
Score = 27.3 bits (59), Expect(2) = 2e-12
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Frame = +2
Query: 215 GNGSDPQASGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
G SGAY+F P+G P S + V+ GP+ EV
Sbjct: 804 GTRPSKDKSGAYLFLPDGKAKPYSQKEPSVVRVVEGPLFSEV 845
>ref|NP_006113.2| mannosidase, alpha, class 2A, member 2 [Homo sapiens]
Length = 1150
Score = 69.7 bits (169), Expect(2) = 4e-12
Identities = 36/118 (30%), Positives = 68/118 (57%), Gaps = 5/118 (4%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIKRIRDYRSEWKIEVHQPIAG 590
+ + D KE+A I T++ + F+TD +G R ++K++ P+
Sbjct: 874 VDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRRYLKKL-------------PLQA 920
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
N+YP+ + Y++D K L++ +++G SS+KDGQ+E++L RRL+ DD +G+ + L +
Sbjct: 921 NFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLKD 978
Score = 26.6 bits (57), Expect(2) = 4e-12
Identities = 18/58 (31%), Positives = 23/58 (39%), Gaps = 1/58 (1%)
Frame = +2
Query: 167 VQANFEQKYKYYIGQDGNGSDPQASGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
V EQ+ + G + SGAY+F P+G P L V GP EV
Sbjct: 787 VDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEV 844
>gb|AAH72937.1| MGC80473 protein [Xenopus laevis]
Length = 1150
Score = 70.9 bits (172), Expect(2) = 4e-12
Identities = 79/321 (24%), Positives = 137/321 (42%), Gaps = 25/321 (7%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIKRIRDYRSEWKIEVHQPIAG 590
I + D KE+A + T++ + TF+TD +G R F K++ P+
Sbjct: 874 IDIRDHVNKEIAMRLSTDIQSGDTFFTDLNGFQIQPRKFFKKL-------------PLQA 920
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL--NE 764
N+YP+ Y++D L++ +++G SS+K+G++E++L RRL+ DD +G+ + L N+
Sbjct: 921 NFYPMPTMAYIQDEQNRLTLHTAQALGVSSLKNGELEVILDRRLMQDDNRGLGQGLKDNK 980
Query: 765 TVC------LDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNW 926
+C ++K+ G V T + PLL+A T + G
Sbjct: 981 RLCSRFRILMEKRSPVNKSLGNQLVSF----PSLLSHMTSMHLNHDPLLMAVTNEKG--- 1033
Query: 927 ANSHVAKFSAMDSTYSLPDNVAML-TLQELEDG-----SVLLRFAHLYEAG-EDKDL--- 1076
+ F + +T ++ L TLQ +DG L+ ++ G E K+L
Sbjct: 1034 --PVLKSFQPLSATLPCDFHILNLRTLQAEDDGLPSPDMALILHRKGFDCGLEAKNLAFN 1091
Query: 1077 --SSLASIDLKRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSAADEKVVRGGPV 1250
+S + L +F IG V +TSL+ A+ P
Sbjct: 1092 CTTSQGKLSLGGLFLGLDIGTVQQTSLTLMYSLAS-----------------------PS 1128
Query: 1251 DPSKLVVELGPMEIRTFIVSF 1313
+ S V + PMEI T+ + F
Sbjct: 1129 NNSNPTVSMDPMEISTYRLRF 1149
Score = 25.4 bits (54), Expect(2) = 4e-12
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 1/53 (1%)
Frame = +2
Query: 182 EQKYKYYIGQDGNGSDPQASGAYIFRPNGT-VPISTDGQVSLTVLRGPILDEV 337
EQK G + SGAY+F P+G P + + V GP EV
Sbjct: 792 EQKINTQFLIYGTRTSKDKSGAYLFLPDGEGKPYTPKDPPVVRVTEGPFFSEV 844
>emb|CAE75350.1| Hypothetical protein CBG23330 [Caenorhabditis briggsae]
Length = 1146
Score = 70.9 bits (172), Expect(2) = 4e-12
Identities = 35/104 (33%), Positives = 60/104 (57%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+A T++ + F+TD +G IKR R + P N+YP++ G+Y+ED
Sbjct: 882 ELALRFSTSVSSGDEFFTDLNGMQMIKRRR--------QAKLPTQANFYPMSAGVYIEDE 933
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+ L++ +++G SS+ GQIE+ML RRL DD +G+ + + +
Sbjct: 934 ATRLTIHSAQALGVSSLSSGQIEIMLDRRLSSDDNRGLQQGVRD 977
Score = 25.4 bits (54), Expect(2) = 4e-12
Identities = 11/40 (27%), Positives = 21/40 (52%)
Frame = +2
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEV 337
NG++ +GAY+F P+G + V+ G ++ +V
Sbjct: 805 NGNEDNPAGAYLFLPDGEARELKKQESDWVVVEGDVVRKV 844
>dbj|BAA92325.1| geraniol-responsible factor 15 [Matricaria chamomilla]
Length = 76
Score = 75.9 bits (185), Expect = 5e-12
Identities = 40/56 (71%), Positives = 44/56 (78%), Gaps = 1/56 (1%)
Frame = +3
Query: 1146 SLSANQERAAMEKKRLKWKAQGSAADEKVV-RGGPVDPSKLVVELGPMEIRTFIVS 1310
SLSANQ R MEKKRL WKA+GS D+ RGGPVDP KLVVEL PMEIRTFI++
Sbjct: 2 SLSANQGRVEMEKKRLVWKAEGSKDDKTAPPRGGPVDPLKLVVELAPMEIRTFILT 57
>emb|CAJ55257.1| Hypothetical protein F58H1.1b [Caenorhabditis elegans]
Length = 1145
Score = 69.7 bits (169), Expect(2) = 1e-11
Identities = 34/104 (32%), Positives = 60/104 (57%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+A +++ + F+TD +G IKR R + P N+YP++ G+Y+ED
Sbjct: 881 ELALRFSSSVNSGDEFFTDLNGMQMIKRRR--------QTKLPTQANFYPMSAGVYIEDD 932
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+ +S+ +++G SS+ GQIE+ML RRL DD +G+ + + +
Sbjct: 933 TTRMSIHSAQALGVSSLSSGQIEIMLDRRLSSDDNRGLQQGVRD 976
Score = 25.0 bits (53), Expect(2) = 1e-11
Identities = 11/46 (23%), Positives = 23/46 (50%)
Frame = +2
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINS 355
NG++ +GAY+F P+G +++G ++ +V N+
Sbjct: 804 NGNEDNPAGAYLFLPDGEARELKKQSSDWILVKGEVVQKVFATPNN 849
>ref|NP_505995.1| F58H1.1 [Caenorhabditis elegans]
emb|CAB00104.1| Hypothetical protein F58H1.1a [Caenorhabditis elegans]
Length = 1143
Score = 69.7 bits (169), Expect(2) = 1e-11
Identities = 34/104 (32%), Positives = 60/104 (57%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+A +++ + F+TD +G IKR R + P N+YP++ G+Y+ED
Sbjct: 879 ELALRFSSSVNSGDEFFTDLNGMQMIKRRR--------QTKLPTQANFYPMSAGVYIEDD 930
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+ +S+ +++G SS+ GQIE+ML RRL DD +G+ + + +
Sbjct: 931 TTRMSIHSAQALGVSSLSSGQIEIMLDRRLSSDDNRGLQQGVRD 974
Score = 25.0 bits (53), Expect(2) = 1e-11
Identities = 11/46 (23%), Positives = 23/46 (50%)
Frame = +2
Query: 218 NGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINS 355
NG++ +GAY+F P+G +++G ++ +V N+
Sbjct: 802 NGNEDNPAGAYLFLPDGEARELKKQSSDWILVKGEVVQKVFATPNN 847
>ref|XP_689538.1| PREDICTED: similar to mannosidase, alpha, class 2A, member 2 [Danio
rerio]
Length = 1193
Score = 67.8 bits (164), Expect(2) = 1e-11
Identities = 35/113 (30%), Positives = 65/113 (57%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPV 605
+ + D N KE+ VT++ + TFYTD +G +I+ R K+ P+ N+YP+
Sbjct: 914 VDIRDQNNKELGMRFVTDIQSGDTFYTDLNGF----QIQPRRYFQKL----PLQANFYPM 965
Query: 606 NLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
Y++D L++ +++G +S+ GQ+E++L RRL+ DD +G+ + L +
Sbjct: 966 PSTAYIQDSQYRLTLHTAQALGVTSLASGQLEVILDRRLMQDDNRGLGQGLKD 1018
Score = 26.6 bits (57), Expect(2) = 1e-11
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Frame = +2
Query: 215 GNGSDPQASGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
G SGAY+F P+G P S + V+ GP+ EV
Sbjct: 843 GTRPSKDKSGAYLFLPDGNAKPYSQREAPIVRVVEGPLFAEV 884
>ref|XP_624759.1| PREDICTED: similar to CG18802-PA [Apis mellifera]
Length = 1119
Score = 72.4 bits (176), Expect = 5e-11
Identities = 39/115 (33%), Positives = 62/115 (53%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPV 605
I + + E A + T++ + FYTD +G + IKR R + P GNYYP+
Sbjct: 842 INISETQNYEFAMRLNTDIASGDQFYTDLNGLNMIKRQRFPKL--------PTQGNYYPM 893
Query: 606 NLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNETV 770
Y+ED L+V+ + +G SS+ GQIE+M RRLL DD +G+ + + + +
Sbjct: 894 AASTYIEDKRVRLTVVTAQPLGVSSMASGQIEIMQDRRLLQDDNRGLGQGITDNL 948
>ref|XP_605840.2| PREDICTED: similar to mannosidase, alpha, class 2A, member 2 isoform
1 [Bos taurus]
Length = 1150
Score = 64.7 bits (156), Expect(2) = 1e-10
Identities = 34/118 (28%), Positives = 66/118 (55%), Gaps = 5/118 (4%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIKRIRDYRSEWKIEVHQPIAG 590
+ + D KE+A I T++ + F+TD +G R ++K++ P+
Sbjct: 874 VDIRDYVNKELALRIRTDINSQGIFFTDLNGFQVQPRRYLKKL-------------PLQA 920
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
N+YP+ + Y++D L++ +++G SS+ DGQ+E++L RRL+ DD +G+ + L +
Sbjct: 921 NFYPMPVMAYLQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKD 978
Score = 26.6 bits (57), Expect(2) = 1e-10
Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 1/42 (2%)
Frame = +2
Query: 215 GNGSDPQASGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
G S SGAY+F P+G P L V GP EV
Sbjct: 803 GTRSSKDKSGAYLFLPDGEAKPYVPRDPPVLRVTEGPFFSEV 844
>ref|XP_877989.1| PREDICTED: similar to mannosidase, alpha, class 2A, member 2
isoform 2 [Bos taurus]
Length = 550
Score = 64.7 bits (156), Expect(2) = 1e-10
Identities = 34/118 (28%), Positives = 66/118 (55%), Gaps = 5/118 (4%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIKRIRDYRSEWKIEVHQPIAG 590
+ + D KE+A I T++ + F+TD +G R ++K++ P+
Sbjct: 275 VDIRDYVNKELALRIRTDINSQGIFFTDLNGFQVQPRRYLKKL-------------PLQA 321
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
N+YP+ + Y++D L++ +++G SS+ DGQ+E++L RRL+ DD +G+ + L +
Sbjct: 322 NFYPMPVMAYLQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKD 379
Score = 26.6 bits (57), Expect(2) = 1e-10
Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 1/42 (2%)
Frame = +2
Query: 215 GNGSDPQASGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
G S SGAY+F P+G P L V GP EV
Sbjct: 204 GTRSSKDKSGAYLFLPDGEAKPYVPRDPPVLRVTEGPFFSEV 245
>ref|XP_642278.1| hypothetical protein DDB0218084 [Dictyostelium discoideum]
gb|EAL68499.1| hypothetical protein DDB0218084 [Dictyostelium discoideum]
Length = 1222
Score = 70.5 bits (171), Expect = 2e-10
Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 4/259 (1%)
Frame = +3
Query: 390 KDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIE 569
++++ET + + D N + V ++ + FYTD+ G + KRI ++
Sbjct: 795 ENYIETGYSIN----GDMNRETTINYKVKDLENDDIFYTDN-GLESRKRIYNH------- 842
Query: 570 VHQPIAGNYYPV----NLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
+ + NYYPV L E+ + + +V VDRS+G +S DG++E+M+HR + DD
Sbjct: 843 -DRSVNQNYYPVLGYIKLKETSENNNHQYTVYVDRSVGATSPSDGEMEIMIHRTMDTDDW 901
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
KGV + D K Y +D + + I + ++ +
Sbjct: 902 KGVNWPSKDIGRSD---------AKLYFNMDLVNNQLQNEKRISLHITNQPIMFVKKH-- 950
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
N ++ K+S + + LP N+ + +L L++ +V LR +++E D + S D
Sbjct: 951 -NNQTGYLLKYSPLSN--QLPSNIHLQSLLTLKNNTVGLRLFNIHEV--DSNTQSTTDTD 1005
Query: 1098 LKRVFPEKKIGKVIETSLS 1154
+F E +I IET LS
Sbjct: 1006 KSTLFNELEISNFIETGLS 1024
>dbj|BAD32345.1| mKIAA0935 protein [Mus musculus]
Length = 256
Score = 70.5 bits (171), Expect = 2e-10
Identities = 75/269 (27%), Positives = 118/269 (43%), Gaps = 28/269 (10%)
Frame = +3
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNETV 770
NYYP+ ++ED L +L +R G SS +GQ+E+MLHRRL ++ +A L +
Sbjct: 2 NYYPMVQSAFIEDDKSRLVLLAERPHGVSSQGNGQVEVMLHRRLWNN----LAWDLKYNL 57
Query: 771 CLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEI-YSPLLLAFTEQDGGN-------- 923
L+ + I+ ++ + P+ G + + P++L D
Sbjct: 58 TLN---DTSIVHPVLWLMLGPKSTMTALHPRSGVALQHGPVVLLKELADEETPVHGPHNP 114
Query: 924 WA-----NSHVAKFSAMDSTYSLPDNVAMLTLQ-------ELEDGSVLLRFAHLYEAGED 1067
W N H+ S TYS + LQ + VLLR HLYEAGED
Sbjct: 115 WPVTLPPNLHLQILSVPGWTYSRSHAQHLRNLQRGHPEKPQANLQRVLLRLRHLYEAGED 174
Query: 1068 KDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKWKAQGSAADEKVVR 1238
LS A++DLK V + +G V+ E SL+ + ++ R W + ++
Sbjct: 175 PVLSRPATVDLKVVL--RGLGSVVAVEERSLTGTWDVQMLQ--RWHWSTKTDH-----LK 225
Query: 1239 GGPVDPSK----LVVELGPMEIRTFIVSF 1313
G P P + ++ + P EIRTF + F
Sbjct: 226 GHPTSPPRPPGGSIITVYPKEIRTFFIKF 254
>ref|XP_642277.1| hypothetical protein DDB0218083 [Dictyostelium discoideum]
gb|EAL68498.1| hypothetical protein DDB0218083 [Dictyostelium discoideum]
Length = 1221
Score = 70.5 bits (171), Expect = 2e-10
Identities = 66/259 (25%), Positives = 118/259 (45%), Gaps = 4/259 (1%)
Frame = +3
Query: 390 KDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIE 569
++++ET + + D N + V ++ + FYTD+ G + KRI ++
Sbjct: 701 ENYIETGYSIN----GDMNRETTINYKVKDLENDDIFYTDN-GLESRKRIYNH------- 748
Query: 570 VHQPIAGNYYPV----NLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDG 737
+ + NYYPV L E+ + + +V VDRS+G +S DG++E+M+HR + DD
Sbjct: 749 -DRTVNQNYYPVLGYIKLKETSENNNHQYTVYVDRSVGATSPSDGEMEIMIHRTMDTDDW 807
Query: 738 KGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDG 917
KGV + D K Y +D + + I + ++ +
Sbjct: 808 KGVNWPSKDIGRSD---------AKLYFNMDLVNNQLQNEKRISLHITNQPIMFVKKH-- 856
Query: 918 GNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASID 1097
N ++ K+S + + LP N+ + +L L++ +V LR +++E D + S D
Sbjct: 857 -NNQTGYLLKYSPLSN--QLPSNIHLQSLLTLKNNTVGLRLFNIHEV--DSNTQSTTDTD 911
Query: 1098 LKRVFPEKKIGKVIETSLS 1154
+F E +I IET LS
Sbjct: 912 KSTLFNELEISNFIETGLS 930
>emb|CAG04580.1| unnamed protein product [Tetraodon nigroviridis]
Length = 1099
Score = 70.5 bits (171), Expect = 2e-10
Identities = 80/348 (22%), Positives = 150/348 (43%), Gaps = 49/348 (14%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
LE + +GP+ ++ EV T++ N+T +TD +G ++R + V+
Sbjct: 678 LEQTYSLGPLRLNT----EVVLRSSTSLQNNRTVFTDDNGYQMMER------RHRTFVNN 727
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAE-- 752
+A N++P+ Y ED L ++ DR+ G SS +GQ+E++L G+ V+
Sbjct: 728 TVARNFFPMVRAAYAEDRLSRLVLVSDRAHGVSSQANGQLEVLLLTNRSMKQGENVSHLK 787
Query: 753 --ALNETVCLDKQC---------------EGLIIQGKYYVKIDPQGEGARWRRTFGQEI- 878
AL V L ++ + +++ +V + G ++ + E+
Sbjct: 788 TAALTHQVMLHRRLWNNLPWNLGYNLTLNDSSVVRPTLWVMLGSIGATSKLHQREAIELQ 847
Query: 879 YSPLLLAFTEQDGGNWA----------------NSHVAKFSAMDSTYSLPDNVAMLTLQE 1010
+ P+++ + N H+ FS YS +V + +Q
Sbjct: 848 HRPVVMVIDTPERVQQVRKPRQGFPLLPVSLPPNLHLLSFSISGWNYSSDHDVHLRRVQS 907
Query: 1011 LED-------GSVLLRFAHLYEAGEDKDLSSLASIDLKRVFPEKKIGKV---IETSLSAN 1160
ED VLLR H++E GED +LS +I++K V + +G+V E SL+
Sbjct: 908 GEDLHSEPDYRRVLLRIMHIFEEGEDAELSKPVTINMKEVL--RGVGEVRTLEERSLTGT 965
Query: 1161 QERAAMEKKRLKW---KAQGSAADEKVVRGGPVDPSKLVVELGPMEIR 1295
+ ++++ R KW K+Q + + V G + + + L P+E R
Sbjct: 966 WDISSLQ--RWKWKTTKSQETRGELYPVFTGWLHQVRAALRLDPLEPR 1011
>dbj|BAA76779.2| KIAA0935 protein [Homo sapiens]
Length = 952
Score = 70.5 bits (171), Expect = 2e-10
Identities = 72/253 (28%), Positives = 112/253 (44%), Gaps = 14/253 (5%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ GP+ ++ +E TN+ + + Y+D++G +R + V+
Sbjct: 698 IEQEYQAGPLELN----REAVLRTSTNLNSQQVIYSDNNGYQMQRR------PYVSYVNN 747
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAE 752
IA NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G
Sbjct: 748 SIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNL 807
Query: 753 ALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGG 920
LN+T + L+ + + A R FG +P L +Q+
Sbjct: 808 TLNDTSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAV 867
Query: 921 NW-ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDL 1076
N H+ S YS L++ G VLLR HLYE GED L
Sbjct: 868 TLPPNLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLYHLYEVGEDPVL 927
Query: 1077 SSLASIDLKRVFP 1115
S +++L+ FP
Sbjct: 928 SQPVTVNLEVNFP 940
>ref|XP_218816.3| PREDICTED: similar to mannosidase, alpha, class 2A, member 2 [Rattus
norvegicus]
Length = 1446
Score = 67.4 bits (163), Expect = 2e-09
Identities = 41/137 (29%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +3
Query: 369 LPGVYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIK 533
LPGV E L+ F + + D KE+A I T++ + TF+TD +G R ++K
Sbjct: 1135 LPGV--EGLSLDVSF---QVDIRDYVNKELALRIHTDIDSQGTFFTDLNGFQVQPRKYLK 1189
Query: 534 RIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLH 713
++ P+ N+YP+ + Y++D + L++ +++G SS+ +GQ+E++L
Sbjct: 1190 KL-------------PLQANFYPMPVMAYIQDSQRRLTLHTAQALGVSSLGNGQLEVILD 1236
Query: 714 RRLLHDDGKGVAEALNE 764
RRL+ DD +G+ + L +
Sbjct: 1237 RRLMQDDNRGLGQGLKD 1253
>dbj|BAE23268.1| unnamed protein product [Mus musculus]
Length = 497
Score = 67.4 bits (163), Expect = 2e-09
Identities = 41/137 (29%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +3
Query: 369 LPGVYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIK 533
LPGV E L+ F + + D KE+A I T++ + TF+TD +G R ++K
Sbjct: 205 LPGV--EGLSLDMSF---QVDIRDYVNKELALRIHTDIDSQGTFFTDLNGFQIQPRQYLK 259
Query: 534 RIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLH 713
++ P+ N+YP+ + Y++D + L++ +++G SS+ +GQ+E++L
Sbjct: 260 KL-------------PLQANFYPMPVMAYIQDSQRRLTLHTAQALGVSSLGNGQLEVILD 306
Query: 714 RRLLHDDGKGVAEALNE 764
RRL+ DD +G+ + L +
Sbjct: 307 RRLMQDDNRGLGQGLKD 323
>gb|AAH55006.1| Man2a2 protein [Mus musculus]
Length = 528
Score = 67.4 bits (163), Expect = 2e-09
Identities = 41/137 (29%), Positives = 76/137 (55%), Gaps = 5/137 (3%)
Frame = +3
Query: 369 LPGVYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIK 533
LPGV E L+ F + + D KE+A I T++ + TF+TD +G R ++K
Sbjct: 236 LPGV--EGLSLDMSF---QVDIRDYVNKELALRIHTDIDSQGTFFTDLNGFQIQPRQYLK 290
Query: 534 RIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLH 713
++ P+ N+YP+ + Y++D + L++ +++G SS+ +GQ+E++L
Sbjct: 291 KL-------------PLQANFYPMPVMAYIQDSQRRLTLHTAQALGVSSLGNGQLEVILD 337
Query: 714 RRLLHDDGKGVAEALNE 764
RRL+ DD +G+ + L +
Sbjct: 338 RRLMQDDNRGLGQGLKD 354
>ref|XP_545863.2| PREDICTED: similar to mannosidase, alpha, class 2A, member 2 [Canis
familiaris]
Length = 1203
Score = 65.9 bits (159), Expect = 5e-09
Identities = 34/118 (28%), Positives = 66/118 (55%), Gaps = 5/118 (4%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSG-----RDFIKRIRDYRSEWKIEVHQPIAG 590
+ + D KE+A I T++ + F+TD +G R ++K++ P+
Sbjct: 927 VDIRDYINKELALRIHTDIDSQGAFFTDLNGFQVQPRRYLKKL-------------PLQA 973
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
N+YP+ + Y++D L++ +++G SS+ DGQ+E++L RRL+ DD +G+ + L +
Sbjct: 974 NFYPMPVMAYIQDAQNRLTLHTAQALGVSSLHDGQLEVILDRRLMQDDNRGLGQGLKD 1031
>ref|XP_599803.2| PREDICTED: similar to mannosidase, alpha, class 2A, member 1 [Bos
taurus]
Length = 707
Score = 65.5 bits (158), Expect = 6e-09
Identities = 32/104 (30%), Positives = 60/104 (57%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+A I +++ + FYTD +G R+ + P+ N YP+ Y++D
Sbjct: 440 EIAMRISSSINSQNRFYTDLNGYQIQPRVTMSKL--------PLQANVYPMTTMAYIQDA 491
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+ L++L +S+G SS+K GQIE+++ RRL+ DD +G+ + +++
Sbjct: 492 ERRLTLLSAQSLGVSSLKSGQIEVIMDRRLMQDDNRGLEQGVHD 535
>ref|XP_545995.2| PREDICTED: similar to mannosidase, alpha, class 2A, member 1 [Canis
familiaris]
Length = 1324
Score = 65.1 bits (157), Expect = 8e-09
Identities = 32/107 (29%), Positives = 62/107 (57%)
Frame = +3
Query: 444 NGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYV 623
+ +E+A I +++ + FYTD +G R+ + P+ N YP+ Y+
Sbjct: 1054 HNREIAMRISSSVNSQNRFYTDLNGYQIQPRMTMSKL--------PLQANVYPMTTMAYI 1105
Query: 624 EDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+D L++L +S+G SS+K+GQIE+++ RRL+ DD +G+ + +++
Sbjct: 1106 QDAKHRLTLLSAQSLGVSSLKNGQIEVIMDRRLMQDDNRGLEQGVHD 1152
>ref|XP_396290.2| PREDICTED: similar to ENSANGP00000010944 [Apis mellifera]
Length = 1099
Score = 64.3 bits (155), Expect = 1e-08
Identities = 34/87 (39%), Positives = 50/87 (57%)
Frame = +3
Query: 498 FYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGS 677
FYTD +G IKR + R I GNY+P+ Y+ED + L++LV+ G +
Sbjct: 850 FYTDLNGHQMIKRTKIDRIG--------IEGNYFPITTMAYIEDTNHRLTLLVNHCQGAA 901
Query: 678 SIKDGQIELMLHRRLLHDDGKGVAEAL 758
S + G +E+ML RR L+DD +G+ E L
Sbjct: 902 SYQPGWLEVMLDRRTLYDDSRGMGEGL 928
>ref|XP_852836.1| PREDICTED: similar to Epididymis-specific alpha-mannosidase precursor
(Mannosidase alpha class 2B member 2) [Canis familiaris]
Length = 702
Score = 64.3 bits (155), Expect = 1e-08
Identities = 65/257 (25%), Positives = 114/257 (44%), Gaps = 22/257 (8%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ VGP+ ++ +E T++ + ++D++G +R+ S
Sbjct: 407 IEQEYRVGPLELN----REAILRTSTSLHNQQVLHSDNNGYQMQRRVFQKYSS------N 456
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
IA NYYP+ ++EDG L +L ++ G SS ++GQ+E+MLHRRL ++ AL
Sbjct: 457 GIALNYYPMAQSAFIEDGRSRLVLLSKQAHGVSSQENGQVEVMLHRRLWNN----FDWAL 512
Query: 759 NETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIY-SPLLLAFTEQDGGNW--- 926
+ + L+ + + ++ + PQ R R+ G + +P++L +
Sbjct: 513 DYDLTLN---DTSTVYPVLWLLLGPQSLTTRLRQRCGLALQRAPVVLLRELNESAQIFPG 569
Query: 927 -----------ANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLY 1052
+ H+ S YS + LQ+ E G VLLR HLY
Sbjct: 570 PQQQQEAVTLPPSLHLQILSIPGWNYSSNHTEHLQDLQKREPGKAKADLRRVLLRLHHLY 629
Query: 1053 EAGEDKDLSSLASIDLK 1103
E G+D LS ++L+
Sbjct: 630 EEGKDPVLSQPVRVNLQ 646
>ref|XP_517864.1| PREDICTED: similar to mannosidase, alpha, class 2A, member 1;
mannosidase, alpha type II; Golgi alpha-mannosidase II;
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase [Pan
troglodytes]
Length = 1160
Score = 63.2 bits (152), Expect(2) = 2e-08
Identities = 31/106 (29%), Positives = 63/106 (59%), Gaps = 1/106 (0%)
Frame = +3
Query: 450 KEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ-PIAGNYYPVNLGIYVE 626
+E+A +I +++ + FYTD +G Y+ + ++ + + P+ N YP+ Y++
Sbjct: 892 REIAMKISSDIKSQNRFYTDLNG---------YQIQPRMTLSKLPLQANVYPMTTMAYIQ 942
Query: 627 DGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
D L++L +S+G SS+ GQIE+++ RRL+ DD +G+ + + +
Sbjct: 943 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQD 988
Score = 20.8 bits (42), Expect(2) = 2e-08
Identities = 13/34 (38%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Frame = +2
Query: 239 SGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
SGAY+F P+G P + V G I EV
Sbjct: 821 SGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEV 854
>ref|NP_002363.2| mannosidase, alpha, class 2A, member 1 [Homo sapiens]
Length = 1144
Score = 63.2 bits (152), Expect(2) = 2e-08
Identities = 31/106 (29%), Positives = 63/106 (59%), Gaps = 1/106 (0%)
Frame = +3
Query: 450 KEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ-PIAGNYYPVNLGIYVE 626
+E+A +I +++ + FYTD +G Y+ + ++ + + P+ N YP+ Y++
Sbjct: 876 REIAMKISSDIKSQNRFYTDLNG---------YQIQPRMTLSKLPLQANVYPMTTMAYIQ 926
Query: 627 DGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
D L++L +S+G SS+ GQIE+++ RRL+ DD +G+ + + +
Sbjct: 927 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQD 972
Score = 20.8 bits (42), Expect(2) = 2e-08
Identities = 13/34 (38%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Frame = +2
Query: 239 SGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
SGAY+F P+G P + V G I EV
Sbjct: 805 SGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEV 838
>gb|AAC50302.1| alpha mannosidase II
sp|Q16706|MA2A1_HUMAN Alpha-mannosidase II (Mannosyl-oligosaccharide
1,3-1,6-alpha-mannosidase) (MAN II) (Golgi
alpha-mannosidase II) (Mannosidase alpha class 2A member
1)
Length = 1144
Score = 63.2 bits (152), Expect(2) = 2e-08
Identities = 31/106 (29%), Positives = 63/106 (59%), Gaps = 1/106 (0%)
Frame = +3
Query: 450 KEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ-PIAGNYYPVNLGIYVE 626
+E+A +I +++ + FYTD +G Y+ + ++ + + P+ N YP+ Y++
Sbjct: 876 REIAMKISSDIKSQNRFYTDLNG---------YQIQPRMTLSKLPLQANVYPMTTMAYIQ 926
Query: 627 DGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
D L++L +S+G SS+ GQIE+++ RRL+ DD +G+ + + +
Sbjct: 927 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQD 972
Score = 20.8 bits (42), Expect(2) = 2e-08
Identities = 13/34 (38%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Frame = +2
Query: 239 SGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
SGAY+F P+G P + V G I EV
Sbjct: 805 SGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEV 838
>dbj|BAA10017.1| golgi alpha-mannosidaseII [Homo sapiens]
Length = 1143
Score = 63.2 bits (152), Expect(2) = 2e-08
Identities = 31/106 (29%), Positives = 63/106 (59%), Gaps = 1/106 (0%)
Frame = +3
Query: 450 KEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ-PIAGNYYPVNLGIYVE 626
+E+A +I +++ + FYTD +G Y+ + ++ + + P+ N YP+ Y++
Sbjct: 876 REIAMKISSDIKSQNRFYTDLNG---------YQIQPRMTLSKLPLQANVYPMTTMAYIQ 926
Query: 627 DGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
D L++L +S+G SS+ GQIE+++ RRL+ DD +G+ + + +
Sbjct: 927 DAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQD 972
Score = 20.8 bits (42), Expect(2) = 2e-08
Identities = 13/34 (38%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Frame = +2
Query: 239 SGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
SGAY+F P+G P + V G I EV
Sbjct: 805 SGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYSEV 838
>ref|XP_545897.2| PREDICTED: similar to Epididymis-specific alpha-mannosidase precursor
(Mannosidase alpha class 2B member 2), partial [Canis
familiaris]
Length = 972
Score = 63.5 bits (153), Expect = 2e-08
Identities = 75/308 (24%), Positives = 129/308 (41%), Gaps = 38/308 (12%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ VGP+ ++ +E T++ + ++D++G +R+ S
Sbjct: 603 IEQEYRVGPLELN----REAILRTSTSLHNQQVLHSDNNGYQMQRRVFQKYSS------N 652
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIE---------------LMLH 713
IA NYYP+ ++EDG L +L ++ G SS ++GQ+E +MLH
Sbjct: 653 GIARNYYPMAQSAFIEDGRSRLVLLSKQAHGVSSQENGQVEVGSGQGGRSDSSSLQVMLH 712
Query: 714 RRLLHDDGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEI-YSPL 890
RRL ++ AL+ + L+ + + ++ + PQ R R+ G + ++P+
Sbjct: 713 RRLWNN----FDWALDYDLTLN---DTSTVYPVLWLLLGPQSLTTRLRQRCGLALQHAPV 765
Query: 891 LLAFTEQDGGNWA--------------NSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS- 1025
+L + + H+ S YS + LQ+ E G
Sbjct: 766 VLLRELNESAQIVPGPQQQQEAVTLPPSLHLQILSIPGWNYSSNHTEHLQDLQKREPGKA 825
Query: 1026 ------VLLRFAHLYEAGEDKDLSSLASIDLKRVFPE-KKIGKVIETSLSANQERAAMEK 1184
VLLR HLYE GED LS ++L+ V +G V E SL+ + +
Sbjct: 826 KADLRRVLLRLHHLYEEGEDPVLSQPVRVNLQAVLQGLGSVGAVEERSLTGTWDGNTLH- 884
Query: 1185 KRLKWKAQ 1208
R W+ Q
Sbjct: 885 -RWSWRTQ 891
>dbj|BAC92711.1| alpha-mannosidase [Drosophila melanogaster]
Length = 1249
Score = 62.8 bits (151), Expect = 4e-08
Identities = 69/283 (24%), Positives = 126/283 (44%), Gaps = 11/283 (3%)
Frame = +3
Query: 498 FYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGS 677
FY+D +G + +RI+ I GNY+P+ G +++D L++L + G +
Sbjct: 982 FYSDQNGFQYHERIKVPAIG--------IEGNYFPITSGAFIQDSRLRLTLLTTHAQGAA 1033
Query: 678 SIKDGQIELMLHRRLLHDDGKGVAEALNETVCLDKQCEGLI--IQGKYYVKIDPQGE--G 845
S + GQ+E+ML RR L+DD +G+ E + ++ + L+ + G +V P +
Sbjct: 1034 SYEPGQLEVMLDRRTLYDDYRGMGEGVVDSRLTRHKFWLLVEDLPGGQHVTQPPSYKVLS 1093
Query: 846 ARWRRTFGQEIYSPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS 1025
+ ++ Y P L + + A + + + LP +V + TL+ L D
Sbjct: 1094 QQAQQLANALRYPPNLYFVSNLEQPELAAALLPLVKLLPKG-PLPCDVHLTTLRTLSDPE 1152
Query: 1026 VLL-----RFAHLYEAGEDKDLSSLASIDLKRVFP--EKKIGKVIETSLSANQERAAMEK 1184
+ L L+ G D +S+ + ++ + P K +G V LS + +E
Sbjct: 1153 LQLFPSASALLVLHRQGFDCSVSAGRELSMEAICPLSSKGLGNVQLGRLSLH----TIEA 1208
Query: 1185 KRLKWKAQGSAADEKVVRGGPVDPSKLVVELGPMEIRTFIVSF 1313
L Q S+ + +R S + L PME+RTF ++F
Sbjct: 1209 TSLTGTEQKSSRESYHIR------SLAEISLEPMELRTFNLTF 1245
>gb|EAA05368.2| ENSANGP00000010944 [Anopheles gambiae str. PEST]
ref|XP_309585.2| ENSANGP00000010944 [Anopheles gambiae str. PEST]
Length = 1112
Score = 62.8 bits (151), Expect = 4e-08
Identities = 31/99 (31%), Positives = 55/99 (55%)
Frame = +3
Query: 462 TEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKE 641
T+I N FY+D +G + KR++ + GNY+P+ G +++D
Sbjct: 910 TDIENGASENPEFYSDLNGFQYQKRVKVSAIG--------VEGNYFPITSGAFIQDDRMR 961
Query: 642 LSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
L++L + G +S++ GQ+E+ML RR L+DD +G+ E +
Sbjct: 962 LTLLTTHAQGAASLEPGQLEVMLDRRTLYDDYRGMGEGV 1000
>ref|XP_601803.2| PREDICTED: similar to Epididymis-specific alpha-mannosidase precursor
(Mannosidase alpha class 2B member 2) [Bos taurus]
Length = 1158
Score = 62.8 bits (151), Expect = 4e-08
Identities = 76/307 (24%), Positives = 128/307 (41%), Gaps = 31/307 (10%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ VGP+ ++ +E TN+ T + Y+D++G +R +
Sbjct: 736 IEQEYRVGPLELN----REAIWRTSTNLNTARVLYSDNNGYQVQRRAYKHHEN------- 784
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
IA NYYP+ +++D L +L +++ G SS GQ+E+MLHRRL V L
Sbjct: 785 NIARNYYPMTQSAFIQDRQSRLVLLSEQAHGVSSQGSGQMEVMLHRRLW---ALSVNVTL 841
Query: 759 NETVCLDK----------------QCEGLIIQGKYYVKIDPQGEGARW----RRTFGQEI 878
N+T + Q G+ +Q + V I E AR + +
Sbjct: 842 NDTSVVHSVLWLLLGPSTLTRDLGQRSGVALQHRPIVLIRELSETARIHPHPQHQEAVTL 901
Query: 879 YSPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEA 1058
+ L G + ++H + DN + E VLLR HLYE
Sbjct: 902 PPSIHLQILSIPGWTYNSNHTKHVKNLRK-----DNKGE---AKAEFRRVLLRLHHLYEV 953
Query: 1059 GEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLKW--------KA 1205
ED S +++L+ V + +G V+ E SL+ + + + R +W +A
Sbjct: 954 DEDPVRSQPVTVNLQSVL--QGLGSVVSVEERSLTGTWDVSTLH--RWRWPTQEPGYLRA 1009
Query: 1206 QGSAADE 1226
QG+ A++
Sbjct: 1010 QGAPAEQ 1016
>ref|XP_413979.1| PREDICTED: similar to Alpha-mannosidase II (Mannosyl-oligosaccharide
1,3-1,6-alpha-mannosidase) (MAN II) (Golgi
alpha-mannosidase II) (Mannosidase alpha class 2A member
1) [Gallus gallus]
Length = 1216
Score = 57.4 bits (137), Expect(2) = 5e-08
Identities = 28/105 (26%), Positives = 58/105 (55%)
Frame = +3
Query: 450 KEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVED 629
+E+A I +++ + FY D +G R+ + P+ N YP+ Y++D
Sbjct: 958 RELAMRISSDINSRNRFYVDLNGYQIQPRLTMSKL--------PLQANIYPMTTMAYIQD 1009
Query: 630 GSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
L++ +S+G +S+K+GQ+E+++ RRL+ DD +G+ + + +
Sbjct: 1010 SGVRLTLHSAQSLGVASLKNGQLEVIMDRRLMQDDNRGLGQGVQD 1054
Score = 25.0 bits (53), Expect(2) = 5e-08
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Frame = +2
Query: 215 GNGSDPQASGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
G S+ SGAY+F P+G P ++ V G I EV
Sbjct: 879 GTTSNRDKSGAYLFLPDGDAKPYIFTDPPTVRVAHGKIFSEV 920
>ref|NP_650494.2| -Man-IIb CG4606-PA [Drosophila melanogaster]
gb|AAF55228.2| CG4606-PA [Drosophila melanogaster]
Length = 1249
Score = 62.4 bits (150), Expect = 5e-08
Identities = 69/283 (24%), Positives = 126/283 (44%), Gaps = 11/283 (3%)
Frame = +3
Query: 498 FYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGS 677
FY+D +G + +RI+ I GNY+P+ G +++D L++L + G +
Sbjct: 982 FYSDQNGFQYHERIKVPAIG--------IEGNYFPITSGAFIQDSRLRLTLLTTHAQGAA 1033
Query: 678 SIKDGQIELMLHRRLLHDDGKGVAEALNETVCLDKQCEGLI--IQGKYYVKIDPQGE--G 845
S + GQ+E+ML RR L+DD +G+ E + ++ + L+ + G +V P +
Sbjct: 1034 SYEPGQLEVMLDRRTLYDDYRGMGEGVVDSRLTRHKFWLLVEDLPGGQHVTQPPSYKVLS 1093
Query: 846 ARWRRTFGQEIYSPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS 1025
+ ++ Y P L + + A + + + LP +V + TL+ L D
Sbjct: 1094 QQAQQLANALRYPPNLYFVSNLEQPELAAALLPLVRLLPKG-PLPCDVHLTTLRTLSDPE 1152
Query: 1026 VLL-----RFAHLYEAGEDKDLSSLASIDLKRVFP--EKKIGKVIETSLSANQERAAMEK 1184
+ L L+ G D +S+ + ++ + P K +G V LS + +E
Sbjct: 1153 LQLFPSASALLVLHRQGFDCSVSAGRELSMEAICPLSSKGLGNVQLGRLSLH----TIEA 1208
Query: 1185 KRLKWKAQGSAADEKVVRGGPVDPSKLVVELGPMEIRTFIVSF 1313
L Q S+ + +R S + L PME+RTF ++F
Sbjct: 1209 TSLTGTEQKSSRESYHIR------SLAEISLEPMELRTFNLTF 1245
>dbj|BAA75817.1| alpha-mannosidase [Drosophila melanogaster]
Length = 1249
Score = 62.4 bits (150), Expect = 5e-08
Identities = 69/283 (24%), Positives = 126/283 (44%), Gaps = 11/283 (3%)
Frame = +3
Query: 498 FYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGS 677
FY+D +G + +RI+ I GNY+P+ G +++D L++L + G +
Sbjct: 982 FYSDQNGFQYHERIKVPAIG--------IEGNYFPITSGAFIQDSRLRLTLLTTHAQGAA 1033
Query: 678 SIKDGQIELMLHRRLLHDDGKGVAEALNETVCLDKQCEGLI--IQGKYYVKIDPQGE--G 845
S + GQ+E+ML RR L+DD +G+ E + ++ + L+ + G +V P +
Sbjct: 1034 SYEPGQLEVMLDRRTLYDDYRGMGEGVVDSRLTRHKFWLLVEDLPGGQHVTQPPSYKVLS 1093
Query: 846 ARWRRTFGQEIYSPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS 1025
+ ++ Y P L + + A + + + LP +V + TL+ L D
Sbjct: 1094 QQAQQLANALRYPPNLYFVSNLEQPELAAALLPLVRLLPKG-PLPCDVHLTTLRTLSDPE 1152
Query: 1026 VLL-----RFAHLYEAGEDKDLSSLASIDLKRVFP--EKKIGKVIETSLSANQERAAMEK 1184
+ L L+ G D +S+ + ++ + P K +G V LS + +E
Sbjct: 1153 LQLFPSASALLVLHRQGFDCSVSAGRELSMEAICPLSSKGLGNVQLGRLSLH----TIEA 1208
Query: 1185 KRLKWKAQGSAADEKVVRGGPVDPSKLVVELGPMEIRTFIVSF 1313
L Q S+ + +R S + L PME+RTF ++F
Sbjct: 1209 TSLTGTEQKSSRESYHIR------SLAEISLEPMELRTFNLTF 1245
>dbj|BAA09510.1| alpha mannosidase II isozyme [Homo sapiens]
sp|P49641|MA2A2_HUMAN Alpha-mannosidase IIx (Mannosyl-oligosaccharide
1,3-1,6-alpha-mannosidase) (MAN IIx) (Mannosidase alpha
class 2A member 2)
Length = 1139
Score = 61.2 bits (147), Expect = 1e-07
Identities = 24/62 (38%), Positives = 44/62 (70%)
Frame = +3
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
P+ N+YP+ + Y++D K L++ +++G SS+KDGQ+E++L RRL+ DD +G+ + L
Sbjct: 906 PLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGL 965
Query: 759 NE 764
+
Sbjct: 966 KD 967
>ref|XP_642245.1| hypothetical protein DDB0205324 [Dictyostelium discoideum]
gb|EAL68302.1| hypothetical protein DDB0205324 [Dictyostelium discoideum]
Length = 1035
Score = 60.8 bits (146), Expect = 2e-07
Identities = 80/339 (23%), Positives = 142/339 (41%), Gaps = 38/339 (11%)
Frame = +3
Query: 432 VDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIE-----VHQPIAGNY 596
V G KE++ + TN+ FYT ++G + +KR +W+I + I N+
Sbjct: 752 VASGWDKEISMKFTTNINNQNIFYT-NNGLEIMKR------QWEIHWNDTFIWSEITSNF 804
Query: 597 YP-VNLGIYVE----DGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALN 761
YP +N G V+ D ++L++L ++ G SS +G+ E++L RR + V E +N
Sbjct: 805 YPMINTGYIVDQQVSDYQQQLTILSKQTFGASSQTNGEFEVLLIRRSNYTQW-SVHEPMN 863
Query: 762 ETVCLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQ---------- 911
+T + L I G DP F EI +P + F
Sbjct: 864 DT--SNPSLRVLCIFG------DP---------NFSNEIRTPHSILFENPLQPVYSLIPN 906
Query: 912 --DGGNWANSHVAKFSAMDSTYSLPDNVAMLTL--QELEDGSVLLRFAHLYEAGEDKDLS 1079
+ +++ F + + SLP N+ +LT Q ++ S+++R ++YE G+ + S
Sbjct: 907 SIPIEKYIDTYNTLFKPLQT--SLPYNLHLLTFTKQWIDSPSIIMRLINIYEIGQSINFS 964
Query: 1080 SLASIDL--------------KRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGSA 1217
+ ++ I ++IET+LSAN E +
Sbjct: 965 KSINFNIGSGDNNNNNNNNNNNGFLTHYNISQIIETTLSANSELSN-------------- 1010
Query: 1218 ADEKVVRGGPVDPSKLVVELGPMEIRTFIVSFDHISDKQ 1334
+ LV+ L P+EI+TF+++ +S KQ
Sbjct: 1011 -----------PTNNLVITLEPLEIKTFLLT---LSPKQ 1035
>emb|CAA43480.1| mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase [Mus musculus]
ref|NP_032575.1| mannosidase 2, alpha 1 [Mus musculus]
sp|P27046|MA2A1_MOUSE Alpha-mannosidase II (Mannosyl-oligosaccharide
1,3-1,6-alpha-mannosidase) (MAN II) (Golgi
alpha-mannosidase II) (Mannosidase alpha class 2A member
1) (AMAN II)
Length = 1150
Score = 60.1 bits (144), Expect = 3e-07
Identities = 31/107 (28%), Positives = 60/107 (56%)
Frame = +3
Query: 444 NGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYV 623
+ +E+ I + + +YTD +G +I+ R+ K+ P+ N YP+ Y+
Sbjct: 875 HNREIVMRISSKINNQNRYYTDLNGY----QIQPRRTMSKL----PLQANVYPMCTMAYI 926
Query: 624 EDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+D L++L +S+G SS+ GQIE+ + RRL+ DD +G+ + +++
Sbjct: 927 QDAEHRLTLLSAQSLGASSMASGQIEVFMDRRLMQDDNRGLGQGVHD 973
>gb|AAR15492.1| glycosyl hydrolase [Arabidopsis arenosa]
Length = 915
Score = 59.3 bits (142), Expect = 5e-07
Identities = 37/110 (33%), Positives = 64/110 (58%), Gaps = 2/110 (1%)
Frame = +3
Query: 435 DDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLG 614
+D + +E+ T++ K FY+D +G +R + KI P+ GNYYP+
Sbjct: 616 NDFDDRELIVRYKTDVDNKKVFYSDLNGFQMSRR----ETYDKI----PLQGNYYPMPSL 667
Query: 615 IYVEDGSK--ELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+++ GSK SV +S+G +S+KDG +E+M+ RRL+ DDG+G+ + +
Sbjct: 668 AFIQ-GSKGQRFSVHSRQSLGVASLKDGWLEIMMDRRLVRDDGRGLGQGV 716
>dbj|BAD45807.1| putative glycosyl hydrolase [Oryza sativa (japonica cultivar-group)]
Length = 1173
Score = 59.3 bits (142), Expect = 5e-07
Identities = 35/106 (33%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
Frame = +3
Query: 444 NGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYV 623
N KE+ T++ FY+D +G +R ++ KI P+ GNYYP+ ++
Sbjct: 880 NDKELIVRFKTDIDNQGVFYSDLNGFQMSRR----QTYDKI----PLQGNYYPMPSLAFL 931
Query: 624 EDG-SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+D SV +S+G +S+K+G +E+ML RRL DDG+G+ + +
Sbjct: 932 QDSLGNRFSVHSKQSLGAASLKNGWLEIMLDRRLTQDDGRGLGQGV 977
>emb|CAF89893.1| unnamed protein product [Tetraodon nigroviridis]
Length = 839
Score = 58.9 bits (141), Expect = 6e-07
Identities = 32/104 (30%), Positives = 59/104 (56%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+A ++T++ FYTD +G +R R+ K+ P+ N YP+ ++D
Sbjct: 639 ELAMRLLTDVANGNRFYTDLNGFQMQQR----RTLPKL----PLQANVYPMTSAALLQDS 690
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+ L++L +S G +S+K G++E+ML RRL DD +G+ + + +
Sbjct: 691 ASRLTLLSAQSQGVASLKPGELEVMLDRRLQQDDNRGLGQGVTD 734
>emb|CAF87950.1| unnamed protein product [Tetraodon nigroviridis]
Length = 385
Score = 58.9 bits (141), Expect = 6e-07
Identities = 32/104 (30%), Positives = 59/104 (56%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+A ++T++ FYTD +G +R R+ K+ P+ N YP+ ++D
Sbjct: 274 ELAMRLLTDVANGNRFYTDLNGFQMQQR----RTLPKL----PLQANVYPMTSAALLQDS 325
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+ L++L +S G +S+K G++E+ML RRL DD +G+ + + +
Sbjct: 326 ASRLTLLSAQSQGVASLKPGELEVMLDRRLQQDDNRGLGQGVTD 369
>emb|CAF87266.1| unnamed protein product [Tetraodon nigroviridis]
Length = 238
Score = 58.9 bits (141), Expect = 6e-07
Identities = 32/104 (30%), Positives = 59/104 (56%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+A ++T++ FYTD +G +R R+ K+ P+ N YP+ ++D
Sbjct: 127 ELAMRLLTDVANGNRFYTDLNGFQMQQR----RTLPKL----PLQANVYPMTSAALLQDS 178
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+ L++L +S G +S+K G++E+ML RRL DD +G+ + + +
Sbjct: 179 ASRLTLLSAQSQGVASLKPGELEVMLDRRLQQDDNRGLGQGVTD 222
>pdb|1O7D|E Chain E, The Structure Of The Bovine Lysosomal A-Mannosidase Suggests
A Novel Mechanism For Low Ph Activation
Length = 126
Score = 58.5 bits (140), Expect = 8e-07
Identities = 41/114 (35%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Frame = +3
Query: 975 LPDNVAMLTLQELEDGSVLLRFAHLYEAGED--KDLSSLASIDLKRVFPEKKIGKVIETS 1148
LP +V +LTL ++LLR H + GED ++LSS ++DL +F I + ET+
Sbjct: 12 LPPSVRLLTLARWGPETLLLRLEHQFAVGEDSGRNLSSPVTLDLTNLFSAFTITNLRETT 71
Query: 1149 LSANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLVVELGPMEIRTFIVS 1310
L+ANQ A RL+W P P + L PMEIRTF+ S
Sbjct: 72 LAANQLLA--YASRLQWTTDTGPTPHP----SPSRPVSATITLQPMEIRTFLAS 119
>ref|NP_196999.1| alpha-mannosidase [Arabidopsis thaliana]
emb|CAC01814.1| alpha-mannosidase-like protein [Arabidopsis thaliana]
gb|AAY90120.1| Golgi alpha-mannosidase II [Arabidopsis thaliana]
Length = 1173
Score = 58.5 bits (140), Expect = 8e-07
Identities = 35/109 (32%), Positives = 61/109 (55%), Gaps = 1/109 (0%)
Frame = +3
Query: 435 DDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPV-NL 611
+D + +E+ T++ K FY+D +G +R + KI P+ GNYYP+ +L
Sbjct: 874 NDFDDRELIVRYKTDVDNKKVFYSDLNGFQMSRR----ETYDKI----PLQGNYYPMPSL 925
Query: 612 GIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ SV +S+G +S+K+G +E+ML RRL+ DDG+G+ + +
Sbjct: 926 AFIQGSNGQRFSVHSRQSLGVASLKEGWLEIMLDRRLVRDDGRGLGQGV 974
>ref|XP_799148.1| PREDICTED: similar to mannosidase, alpha, class 2A, member 2,
partial [Strongylocentrotus purpuratus]
Length = 184
Score = 57.8 bits (138), Expect = 1e-06
Identities = 29/93 (31%), Positives = 54/93 (58%)
Frame = +3
Query: 486 TNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRS 665
+++ FYTD +G KR KI P+ ++YP+ Y+ED S L++ ++
Sbjct: 17 SDRVFYTDLNGFQMQKR--------KILDKLPLQAHFYPMPAMAYIEDSSTRLTLHSAQA 68
Query: 666 IGGSSIKDGQIELMLHRRLLHDDGKGVAEALNE 764
+G S +K+G +E++L RRL+ DD +G+ + + +
Sbjct: 69 LGVSGLKEGWLEVVLDRRLMQDDSRGLQQGVTD 101
>ref|XP_646960.1| hypothetical protein DDB0202336 [Dictyostelium discoideum]
gb|EAL73086.1| hypothetical protein DDB0202336 [Dictyostelium discoideum]
Length = 1079
Score = 57.8 bits (138), Expect = 1e-06
Identities = 70/258 (27%), Positives = 114/258 (44%), Gaps = 18/258 (6%)
Frame = +3
Query: 441 GNGKEVATEIVTNMVTN-KTFYTDSSGRDFIKRIRDYRSEWKIEVH-QPIAGNYYPVNLG 614
G KE+ ++ + + N KTFYT S+G + I+R +Y+S + IAGNYYPV
Sbjct: 810 GWNKEIGSQFSSESINNDKTFYT-SNGLELIER--NYKSLFNDTTEFNMIAGNYYPVINT 866
Query: 615 IYVED--GSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNETVCLDKQC 788
I + D K+L++L +S G SS +G++ L+ RR LNET+
Sbjct: 867 IQILDNKSKKQLTILTKQSFGASSQNNGELNLLFIRR-----STDQFVTLNETM---NDI 918
Query: 789 EGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAF---TEQDGGNWANSHVAKFSAM 959
+I+ K E R + E +PLL + ++ W + + F
Sbjct: 919 SNPLIKIKVLFGNSNSIENIRTPHSLLLE--NPLLPIYSIVSDITIDKWISIYNTVFKPF 976
Query: 960 DSTYSLPDNVAMLTL--------QELEDGSVL---LRFAHLYEAGEDKDLSSLASIDLKR 1106
+ SLP N+ +LT Q+ + + L +RF ++YE + + S L
Sbjct: 977 KT--SLPYNLHLLTFTKQQQQQQQDFNEDNPLDYFIRFLNIYEISQSESFSQPIEFKLTN 1034
Query: 1107 VFPEKKIGKVIETSLSAN 1160
F I + E+SL+ N
Sbjct: 1035 YFNNFNITNIRESSLTFN 1052
>gb|EAL28526.1| GA18295-PA [Drosophila pseudoobscura]
Length = 1259
Score = 57.4 bits (137), Expect = 2e-06
Identities = 67/293 (22%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Frame = +3
Query: 498 FYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGS 677
FY+D +G + +RI+ I GNY+P+ G +++D L++L + G +
Sbjct: 994 FYSDQNGFQYHERIKVPAIG--------IEGNYFPITSGAFIQDTRLRLTLLTTHAQGAA 1045
Query: 678 SIKDGQIELMLHRRLLHDDGKGVAEALNETVCLDKQCEGLIIQGKYYVKIDPQGEGARWR 857
S + GQ+E+ML RR L+DD +G+ E + + + + K+++ ++ G
Sbjct: 1046 SYEPGQLEVMLDRRTLYDDYRGMGEGV---------VDSHLTRHKFWLLVEDMPRGQHAA 1096
Query: 858 RTFGQEIYS----PLLLAFTEQDGGNWANSHVAKFSAMDSTY------SLPDNVAMLTLQ 1007
+ G ++ S L A + +S S + +LP +V + TL+
Sbjct: 1097 KPPGYQVPSMQGQMLANALRYPPNLYFLSSVEQPLSGLQDQVRLLPKGALPCDVHLTTLR 1156
Query: 1008 ELEDGSVLL-----RFAHLYEAGEDKDLSSLA--SIDLKRVFPEKKIG----KVIETSLS 1154
L D + L L+ G D +S++ + L V P G ++ + SL
Sbjct: 1157 TLSDPELQLFPSASALMVLHRQGFDCSVSAVGGRELGLDAVCPLSNGGLGPVQLGKLSLR 1216
Query: 1155 ANQERAAMEKKRLKWKAQGSAADEKVVRGGPVDPSKLVVELGPMEIRTFIVSF 1313
+ + ++ K KA+ + + V L PME+RTF ++F
Sbjct: 1217 TIEATSLTGLEQAKEKAKENFRIRSLAE----------VSLQPMELRTFNLTF 1259
>gb|AAB62719.1| alpha-mannosidase II [Spodoptera frugiperda]
Length = 1130
Score = 54.7 bits (130), Expect = 1e-05
Identities = 39/154 (25%), Positives = 73/154 (47%), Gaps = 7/154 (4%)
Frame = +3
Query: 318 GPYWMKCTSR*IHGFIRLPGVYKEKDFLETEFIVGPIPVD-DGNGKEVATEIVTNMVTN- 491
GP + T+ + + +Y D + + I+ VD + K TE+ + T+
Sbjct: 796 GPISTEITTMYLPFLVHTIRIYNVPDPVLSRAILLETDVDFEAPPKNRETELFMRLQTDI 855
Query: 492 -----KTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLV 656
FYTD +G + KR++ + I NYYP+ ++D L++L
Sbjct: 856 QNGDIPEFYTDQNGFQYQKRVKVNKLG--------IEANYYPITTMACLQDEETRLTLLT 907
Query: 657 DRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ + G ++ + G++E+ML RR L+DD +G+ E +
Sbjct: 908 NHAQGAAAYEPGRLEVMLDRRTLYDDFRGIGEGV 941
>gb|EAL40242.1| ENSANGP00000028437 [Anopheles gambiae str. PEST]
ref|XP_557731.1| ENSANGP00000028437 [Anopheles gambiae str. PEST]
Length = 128
Score = 54.7 bits (130), Expect = 1e-05
Identities = 35/98 (35%), Positives = 55/98 (56%)
Frame = +3
Query: 921 NWANSHVAKFSAMDSTYSLPDNVAMLTLQELEDGSVLLRFAHLYEAGEDKDLSSLASIDL 1100
+W + +SA+ + SLP NV +LT + ++ S+L+RF HL E ED S ++
Sbjct: 32 DWQKQYTNIYSAL--SLSLPLNVHLLTFEPWKENSILVRFEHLLEKDEDPMYSKPVRFNI 89
Query: 1101 KRVFPEKKIGKVIETSLSANQERAAMEKKRLKWKAQGS 1214
+ VF + I +V E +L+ANQ R + RLK+K S
Sbjct: 90 QDVFRQFSIEEVREMTLAANQLRE--DSTRLKFKPDPS 125
>ref|XP_606944.2| PREDICTED: similar to Epididymis-specific alpha-mannosidase
precursor (Mannosidase alpha class 2B member 2), partial
[Bos taurus]
Length = 756
Score = 54.7 bits (130), Expect = 1e-05
Identities = 34/112 (30%), Positives = 62/112 (55%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E E+ VGP+ ++ +E T++ T + ++D++G +R ++ +
Sbjct: 554 IEQEYRVGPLELN----REAILRTSTDLNTGQVLHSDNNGYQMQRR------PYRQNMWN 603
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDD 734
IA NYYP+ +ED L +L +++ G SS +GQ+E+MLHRRL ++D
Sbjct: 604 TIARNYYPMVQMASIEDLPSRLVLLSEQAHGISSQGNGQVEVMLHRRLWNND 655
>gb|EAS02486.1| conserved hypothetical protein [Tetrahymena thermophila SB210]
Length = 204
Score = 54.3 bits (129), Expect = 1e-05
Identities = 26/59 (44%), Positives = 41/59 (69%), Gaps = 2/59 (3%)
Frame = +3
Query: 549 RSEWKIEVHQPIAGNYYPVNLGIYVEDGSKELSVLV--DRSIGGSSIKDGQIELMLHRR 719
+S + ++ +P++GNYYP+ I +ED + VLV DRS GG+S+ GQIE+M+HR+
Sbjct: 15 QSNFFLQQTEPVSGNYYPIGAIIGLEDQQTKQRVLVVNDRSQGGTSLNQGQIEIMIHRK 73
>ref|XP_517094.1| PREDICTED: similar to Mannosidase, alpha, class 2B, member 2 [Pan
troglodytes]
Length = 1198
Score = 52.8 bits (125), Expect = 4e-05
Identities = 56/185 (30%), Positives = 81/185 (43%), Gaps = 14/185 (7%)
Frame = +3
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLH--DDGKGVAEALNE 764
NYYP+ ++EDG L +L +R+ G SS +GQ+E+MLHRRL + D G LN+
Sbjct: 842 NYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLND 901
Query: 765 TVCLDKQCEGLIIQGKYYVKIDPQGEGARWRR---TFGQEI-YSPLLLAFTEQDGGNW-A 929
T + L+ + + A R FG +P L +Q+
Sbjct: 902 TSVVHPVLWLLLGSWSLTTALRQRSALALQHRPVVLFGDLAGTAPKLPGPQQQEAVTLPP 961
Query: 930 NSHVAKFSAMDSTYSLPDNVAMLTLQELEDGS-------VLLRFAHLYEAGEDKDLSSLA 1088
N H+ S YS L++ G VLLR HLYE GED LS
Sbjct: 962 NLHLQILSIPGWRYSSNHTEHSQNLRKGHRGEAQADLRRVLLRLHHLYEVGEDPVLSQPV 1021
Query: 1089 SIDLK 1103
+++L+
Sbjct: 1022 TVNLE 1026
>pir||JC4037 alpha-mannosidase II, Golgi - fruit fly (Drosophila melanogaster)
Length = 1108
Score = 40.4 bits (93), Expect(2) = 5e-05
Identities = 27/102 (26%), Positives = 47/102 (46%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYVEDG 632
E+ + T++ + FYTD +G FIKR R + P+ NYYP+ G+++E
Sbjct: 852 EIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDK--------LPLQANYYPIPSGMFIEIR 903
Query: 633 SKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEAL 758
+ V+ + + L RRL DD +G+ + +
Sbjct: 904 RRFALVICSGCLLVFLSLYIILNFALRRRLASDDERGLGQGV 945
Score = 31.6 bits (70), Expect(2) = 5e-05
Identities = 28/99 (28%), Positives = 42/99 (42%)
Frame = +2
Query: 83 NLQVGQGNLKLQYNEAGKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+L+VG G L ++E G L ++ K+ Y G S SGAY+F P
Sbjct: 740 SLRVGNGPT-LAFSEQGLLKSIQLTQDSPHVPVHFKFLKY----GVRSHGDRSGAYLFLP 794
Query: 263 NGTVPISTDGQVSLTVLRGPILDEVHQQINSWIYQITRR 379
NG GQ + V +G + V + S ++Q R
Sbjct: 795 NGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR 833
>dbj|BAE42419.1| unnamed protein product [Mus musculus]
dbj|BAE42071.1| unnamed protein product [Mus musculus]
Length = 516
Score = 52.4 bits (124), Expect = 6e-05
Identities = 24/69 (34%), Positives = 39/69 (56%)
Frame = +2
Query: 185 QKYKYYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLTVLRGPILDEVHQQINSWIY 364
Q + +Y G+ QASGAYIFRPN PI +++++ ++ EVHQ ++W
Sbjct: 437 QGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISLVKTALVQEVHQNFSAWCS 496
Query: 365 QITRRLQGE 391
Q+ R +G+
Sbjct: 497 QVIRLYKGQ 505
>emb|CAE66941.1| Hypothetical protein CBG12333 [Caenorhabditis briggsae]
Length = 961
Score = 52.4 bits (124), Expect = 6e-05
Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 3/102 (2%)
Frame = +3
Query: 450 KEVATEIVTNMVTN---KTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIY 620
KE TE++T TN +TDS G ++R D+ PI NYYP+
Sbjct: 699 KERNTELMTRFTTNWAKPITFTDSVGMQLLRR--DF-------YRLPIQSNYYPMPTSAV 749
Query: 621 VEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGV 746
+++G + +S++ + G +++G +E+ + R L DDGKG+
Sbjct: 750 LQEGKQRISIVSNVEHGARFLENGSVEINIDRILNQDDGKGL 791
>gb|AAL38616.1| AT5g14950/F2G14_70 [Arabidopsis thaliana]
gb|AAK96611.1| AT5g14950/F2G14_70 [Arabidopsis thaliana]
Length = 270
Score = 51.6 bits (122), Expect = 9e-05
Identities = 24/61 (39%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
Frame = +3
Query: 579 PIAGNYYPV-NLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEA 755
P+ GNYYP+ +L + SV +S+G +S+K+G +E+ML RRL+ DDG+G+ +
Sbjct: 11 PLQGNYYPMPSLAFIQGSNGQRFSVHSRQSLGVASLKEGWLEIMLDRRLVRDDGRGLGQG 70
Query: 756 L 758
+
Sbjct: 71 V 71
>ref|XP_688638.1| PREDICTED: similar to mannosidase, alpha, class 2A, member 2,
partial [Danio rerio]
Length = 305
Score = 43.5 bits (101), Expect(2) = 2e-04
Identities = 25/86 (29%), Positives = 47/86 (54%)
Frame = +3
Query: 426 IPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPV 605
+ + D N KE+A VT++ + TFYTD +G +I+ R K+ P+ N+YP+
Sbjct: 226 VDIRDQNNKELAMRFVTDIQSGDTFYTDLNGF----QIQPRRYFQKL----PLQANFYPM 277
Query: 606 NLGIYVEDGSKELSVLVDRSIGGSSI 683
Y++D L++ +++G +S+
Sbjct: 278 PSTAYIQDSQYRLTLHTAQALGVTSL 303
Score = 26.6 bits (57), Expect(2) = 2e-04
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Frame = +2
Query: 215 GNGSDPQASGAYIFRPNGTV-PISTDGQVSLTVLRGPILDEV 337
G SGAY+F P+G P S + V+ GP+ EV
Sbjct: 155 GTRPSKDKSGAYLFLPDGNAKPYSQREAPIVRVVEGPLFAEV 196
>gb|AAB52345.2| Hypothetical protein F48C1.1 [Caenorhabditis elegans]
ref|NP_001021474.1| F48C1.1 [Caenorhabditis elegans]
Length = 1064
Score = 50.1 bits (118), Expect = 3e-04
Identities = 32/102 (31%), Positives = 53/102 (51%), Gaps = 3/102 (2%)
Frame = +3
Query: 450 KEVATEIVTNMVTN---KTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIY 620
KE TE++T T YTDS G ++R D+ +K+ P+ NYYP+
Sbjct: 802 KERNTELMTRFSTKWDKPLTYTDSVGMQLLRR--DF---YKL----PVQSNYYPMPTAAV 852
Query: 621 VEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGV 746
++ G + LS++ + G ++ G +E+ + R L DDGKG+
Sbjct: 853 LQSGKQRLSIVSNVEHGARFLESGTVEINIDRILNQDDGKGL 894
>dbj|BAD94717.1| alpha-mannosidase [Arabidopsis thaliana]
Length = 63
Score = 49.7 bits (117), Expect = 4e-04
Identities = 24/50 (48%), Positives = 33/50 (66%), Gaps = 3/50 (6%)
Frame = +3
Query: 1176 MEKKRLKWKAQGSAA---DEKVVRGGPVDPSKLVVELGPMEIRTFIVSFD 1316
MEKKRL WK +G + ++K RG +DP KL +EL PMEIRT ++ +
Sbjct: 1 MEKKRLVWKVEGEGSYGEEKKAKRGREIDPRKLEMELYPMEIRTVLIHLE 50
>ref|XP_852823.1| PREDICTED: similar to mannosidase, alpha, class 2B, member 2 [Canis
familiaris]
Length = 208
Score = 48.5 bits (114), Expect = 8e-04
Identities = 36/130 (27%), Positives = 65/130 (50%)
Frame = +3
Query: 591 NYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALNETV 770
NYYP+ ++EDG L +L ++ G SS ++GQ+E+MLHRRL ++ AL+ +
Sbjct: 25 NYYPMAQSAFIEDGRSRLVLLSKQAHGVSSQENGQVEVMLHRRLWNN----FDWALDYDL 80
Query: 771 CLDKQCEGLIIQGKYYVKIDPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWANSHVAKF 950
L+ + + ++ + PQ R R+ G + ++ E +G S +A+
Sbjct: 81 TLN---DTSTVYPVLWLLLGPQSLTTRLRQRCGLALQHAPVVLLRELNGARVGRSRIAR- 136
Query: 951 SAMDSTYSLP 980
+ S S+P
Sbjct: 137 NGGQSILSIP 146
>gb|AAP92617.1| Ab2-450 [Rattus norvegicus]
Length = 1449
Score = 47.0 bits (110), Expect = 0.002
Identities = 27/102 (26%), Positives = 53/102 (51%)
Frame = +3
Query: 399 LETEFIVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ 578
+E ++ VGP+ ++ +E +++ + + Y+D++G +R +K
Sbjct: 847 IEQQYQVGPLDLN----REAILRTSSDLNSQQVLYSDNNGYQMQRR------PYKAFKSN 896
Query: 579 PIAGNYYPVNLGIYVEDGSKELSVLVDRSIGGSSIKDGQIEL 704
PI NYYP+ ++ED L +L +R G SS ++GQ+E+
Sbjct: 897 PIPRNYYPMVQSAFIEDDKSRLVLLAERPHGVSSQENGQVEV 938
>ref|XP_637323.1| hypothetical protein DDB0187376 [Dictyostelium discoideum]
gb|EAL63817.1| hypothetical protein DDB0187376 [Dictyostelium discoideum]
Length = 994
Score = 46.2 bits (108), Expect = 0.004
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = +3
Query: 444 NGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLGIYV 623
NG T++ N+ Y+D+ G + + R S +EV + +YYP +Y+
Sbjct: 712 NGTTTINRFTTDIDNNRELYSDN-GLEMMHR--KSISSQSVEVGRETQ-SYYPTINSVYI 767
Query: 624 EDGS--KELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGV 746
E S K DRS G SS G +E+ LHR L ++DGKG+
Sbjct: 768 ESQSTGKRFVCNNDRSRGVSSQGQGCLEMALHRSLTYEDGKGL 810
>ref|XP_688626.1| PREDICTED: similar to Alpha-mannosidase II
(Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)
(MAN II) (Golgi alpha-mannosidase II) (Mannosidase alpha
class 2A member 1) [Danio rerio]
Length = 279
Score = 45.4 bits (106), Expect = 0.007
Identities = 24/91 (26%), Positives = 45/91 (49%)
Frame = +3
Query: 414 IVGPIPVDDGNGKEVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGN 593
I + + +E+A I +++ + F+TD +G R K P+ N
Sbjct: 147 ICNTVDIRGETNREIAMRITSDLNSKDRFFTDLNGYQVQPR--------KTMAKLPLQAN 198
Query: 594 YYPVNLGIYVEDGSKELSVLVDRSIGGSSIK 686
+YP+ +Y++D S LS+L +S+G +S+K
Sbjct: 199 FYPMTSMLYLQDSSARLSLLTAQSLGAASLK 229
>ref|XP_875484.1| PREDICTED: similar to Epididymis-specific alpha-mannosidase precursor
(Mannosidase alpha class 2B member 2) [Bos taurus]
Length = 159
Score = 40.8 bits (94), Expect = 0.17
Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Frame = +3
Query: 1026 VLLRFAHLYEAGEDKDLSSLASIDLKRVFPEKKIGKVI---ETSLSANQERAAMEKKRLK 1196
VLLR HLYE +D LS +++L+ V + +G V+ E SL+ + E +R
Sbjct: 63 VLLRLQHLYEVDQDPVLSRPVTVNLQSVL--RGLGSVVSVEERSLTGTWD--VSEMRRWT 118
Query: 1197 WKAQGSAADEKVVRGGPVDPSK----LVVELGPMEIRTFIVSF 1313
W +Q D RG PS V + P EIRTF + F
Sbjct: 119 WSSQ----DPHGHRGNSSQPSPPPRGPEVTIYPKEIRTFFIHF 157
>gb|AAW27826.1| SJCHGC06726 protein [Schistosoma japonicum]
Length = 288
Score = 40.0 bits (92), Expect = 0.29
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 17/115 (14%)
Frame = +3
Query: 468 IVTNMVT-NKTFYTDSSGRDFIKRIRDYRSEWKIEVHQ--PIAGNYYPVNLGIYVE---- 626
I T+++ ++ FYTDS+ FI+R + H P+ GN YP+ G Y+E
Sbjct: 3 IQTDLINKDRAFYTDSNCFQFIRR----------QYHDKIPLQGNVYPIACGAYLEQEMD 52
Query: 627 -----DGS-----KELSVLVDRSIGGSSIKDGQIELMLHRRLLHDDGKGVAEALN 761
D S + L++ G S + GQI + + RR DD +G LN
Sbjct: 53 SFLNNDNSQTKQFQRLNLFTSYPTGVVSPEIGQINVWIDRRSSRDDLRGAQSNLN 107
>ref|YP_437108.1| Polyketide synthase modules and related protein [Hahella chejuensis
KCTC 2396]
gb|ABC32683.1| Polyketide synthase modules and related protein [Hahella chejuensis
KCTC 2396]
Length = 955
Score = 39.3 bits (90), Expect = 0.49
Identities = 23/77 (29%), Positives = 34/77 (44%)
Frame = +3
Query: 828 DPQGEGARWRRTFGQEIYSPLLLAFTEQDGGNWANSHVAKFSAMDSTYSLPDNVAMLTLQ 1007
DPQG+ R+ F Q YSP + + E G +A+ SA++ Y P+ L +
Sbjct: 794 DPQGQALAMRKAFVQAGYSPARVQYVETHGTGTRLGDIAELSALNEVYLAPERSGPLKV- 852
Query: 1008 ELEDGSVLLRFAHLYEA 1058
GSV H + A
Sbjct: 853 ----GSVKSNIGHTFAA 865
>ref|XP_653893.1| hypothetical protein 69.t00014 [Entamoeba histolytica HM-1:IMSS]
gb|EAL48507.1| hypothetical protein 69.t00014 [Entamoeba histolytica HM-1:IMSS]
Length = 779
Score = 38.9 bits (89), Expect = 0.64
Identities = 31/119 (26%), Positives = 48/119 (40%), Gaps = 18/119 (15%)
Frame = +2
Query: 5 ASANLKKSAHISSKSTQYSPQG--SESSNLQVGQGNLKLQYNEAGKLSLYSDSK------ 160
A AN+ +A SK Q + + ++ + + Y GK ++ +D K
Sbjct: 196 AGANI--NASYDSKKVQANAKAGINKDGSSTTSSASASATYKPNGKTTISADGKVSKTNG 253
Query: 161 -TMVQANFEQKYK---------YYIGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLT 307
T +Q N Y +D NG AS + ++PNG IS DG+VS T
Sbjct: 254 QTTIQGNANASYNGDKLQANAGVNFNKDSNGKTTSASASATYKPNGKTTISADGKVSKT 312
Score = 36.6 bits (83), Expect = 3.2
Identities = 25/95 (26%), Positives = 38/95 (40%), Gaps = 16/95 (16%)
Frame = +2
Query: 71 SESSNLQVGQGNLKLQYNEAGKLSLYSDSK-------TMVQANFEQKYK---------YY 202
++ SN + + Y GK ++ +D K T +Q N Y
Sbjct: 279 NKDSNGKTTSASASATYKPNGKTTISADGKVSKTNGQTTIQGNANASYNGDKLQANAGVN 338
Query: 203 IGQDGNGSDPQASGAYIFRPNGTVPISTDGQVSLT 307
+D NG AS + ++PN IS DG+VS T
Sbjct: 339 FNKDSNGKTTSASASATYKPNDKTTISADGKVSKT 373
>gb|AAL11728.1| membrane protein NBR1 [Mus musculus]
Length = 727
Score = 38.9 bits (89), Expect = 0.64
Identities = 36/86 (41%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
Frame = -1
Query: 1293 GSPLAPAQRRASKDPQ----GHPEPPSRPPQNLAPSISNASSPWLRVLGLPISLSR-*PC 1129
GS L Q R +D Q H R P NL S ASSP V GLP +LSR PC
Sbjct: 527 GSSLGWNQLRLERDSQRGRASHRSRDQRHPHNLTASGHGASSP--EVAGLPAALSRSAPC 584
Query: 1128 -QSSSPGTLS*GRYSLKTKDPCPPRP 1054
Q S G S G S T PP P
Sbjct: 585 GQCESSGVDSPGVDSPATMHEVPPAP 610
>ref|XP_716055.1| hypothetical protein CaO19_2215 [Candida albicans SC5314]
ref|XP_715996.1| hypothetical protein CaO19_9760 [Candida albicans SC5314]
gb|EAK97047.1| hypothetical protein CaO19.2215 [Candida albicans SC5314]
gb|EAK96987.1| hypothetical protein CaO19.9760 [Candida albicans SC5314]
Length = 500
Score = 37.7 bits (86), Expect = 1.4
Identities = 45/182 (24%), Positives = 76/182 (41%), Gaps = 17/182 (9%)
Frame = +3
Query: 162 LWFKQTLSRNTSIILDRMEMEVILR------LLEHTYSALMA--QFQSVLMGRFLSQFCV 317
L FK L+ I+D+ E EVI+R L + Y+ L A F+ L RF+ + C
Sbjct: 287 LVFKWVLNFTAKAIIDQAETEVIVRPNSAVPLAKLAYAILQAIPDFEYYLNARFIKK-CP 345
Query: 318 GPYWMKCT-----SR*IHGFIRLPGVYKEKDFLETEFIVGPIPVDDGNGKEVATEIVTNM 482
C+ R G+ R G E++ E + G + V A +TN
Sbjct: 346 YIIGYNCSIDSEEGRERMGWKRPDGSKWEEETKYDERMGGIVSV------WAAMTTITNH 399
Query: 483 VTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVN----LGIYVEDGSKELSV 650
+ K+ Y+ + F+ R + ++ + H I GN++ LG+Y K + +
Sbjct: 400 GSQKSLYSFEASWQFLARTANLQTSMLVNTHFTILGNWWEAAGASFLGVYGNQSQKLMYI 459
Query: 651 LV 656
+V
Sbjct: 460 VV 461
>dbj|BAA14368.1| surface protein antigen precursor [Streptococcus sobrinus]
Length = 1566
Score = 37.4 bits (85), Expect = 1.9
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Frame = +2
Query: 134 KLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASG-AYIFRPNGTVPISTDGQVSLTV 310
KL Y D + ++A E+ K+ +DGN S+P A Y PN + + TDG+ +
Sbjct: 475 KLQAYQDEQAAIKAALEELEKHK-NEDGNLSEPSAQSLVYDLEPNAQISLVTDGK----L 529
Query: 311 LRGPILDE 334
L+ LDE
Sbjct: 530 LKASALDE 537
>dbj|BAD91216.1| antigen I/II [Streptococcus downei]
Length = 1565
Score = 37.4 bits (85), Expect = 1.9
Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Frame = +2
Query: 134 KLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASG-AYIFRPNGTVPISTDGQVSLTV 310
KL Y D + ++A E+ K+ +DGN S+P A Y PN + + TDG+ +
Sbjct: 474 KLQAYQDEQAAIKAALEELEKHK-NEDGNLSEPSAQSLVYDLEPNAQISLVTDGK----L 528
Query: 311 LRGPILDE 334
L+ LDE
Sbjct: 529 LKASALDE 536
>ref|NP_504860.1| F07G11.1 [Caenorhabditis elegans]
gb|AAG24050.1| Hypothetical protein F07G11.1 [Caenorhabditis elegans]
Length = 317
Score = 37.4 bits (85), Expect = 1.9
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 11/138 (7%)
Frame = +3
Query: 453 EVATEIVTNMVTNKTFYTDSSGRDFIKRIRDYRSEWKIEVHQPIAGNYYPVNLG------ 614
E+ ++ N + K + SG +K R YR E+K E+ + + Y+ N
Sbjct: 159 EINRDLYENKLGGKYYQYAVSGEKGMKNSRVYREEYKEEITEHVGAEYFLKNFVRKDRVD 218
Query: 615 -IYVEDGSKELSVLVDRSIGGSSIKDG----QIELMLHRRLLHDDGKGVAEALNETVCLD 779
++++ E S L GG+ K+G QI + LH+ LL + +G E ++ +
Sbjct: 219 ILWIDIEGNEFSFLEQIHNGGTIDKEGIKICQINVELHKDLL-EKPEGEMEKFHDFIF-- 275
Query: 780 KQCEGLIIQGKYYVKIDP 833
I++ Y+ I+P
Sbjct: 276 -----KILEDGKYISINP 288
>emb|CAD16742.1| PROBABLE DNA-DIRECTED RNA POLYMERASE (BETA' CHAIN) PROTEIN [Ralstonia
solanacearum]
ref|NP_521154.1| DNA-directed RNA polymerase beta' subunit [Ralstonia solanacearum
GMI1000]
sp|Q8XUZ9|RPOC_RALSO DNA-directed RNA polymerase beta' chain (RNAP beta' subunit)
(Transcriptase beta' chain) (RNA polymerase beta'
subunit)
Length = 1409
Score = 37.0 bits (84), Expect = 2.4
Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
Frame = +3
Query: 1029 LLRFAHLYEAGEDKDLSSLASIDLKRVFPEKKIGK--VIETSLSANQERAAMEKKRLKWK 1202
L R A L+EA KD + LA + F + GK ++ T L N + K++
Sbjct: 1145 LPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEKQVLV 1204
Query: 1203 AQGSAADE-KVVRGGPVDPSKLVVELGPMEIRTFIVSFDHISDKQQL 1340
G ++ +++ GP DP ++ G E+ T+IV D + D +L
Sbjct: 1205 HDGQVVNKGEMIVEGPADPHDILRLKGVEELATYIV--DEVQDVYRL 1249
>ref|ZP_00946351.1| DNA-directed RNA polymerase beta chain [Ralstonia solanacearum UW551]
gb|EAP71162.1| DNA-directed RNA polymerase beta chain [Ralstonia solanacearum UW551]
Length = 1409
Score = 37.0 bits (84), Expect = 2.4
Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 3/107 (2%)
Frame = +3
Query: 1029 LLRFAHLYEAGEDKDLSSLASIDLKRVFPEKKIGK--VIETSLSANQERAAMEKKRLKWK 1202
L R A L+EA KD + LA + F + GK ++ T L N + K++
Sbjct: 1145 LPRVAELFEARSPKDAAVLAEVTGTTSFGKDTKGKQRLVITDLDGNAHEFLIAKEKQVLV 1204
Query: 1203 AQGSAADE-KVVRGGPVDPSKLVVELGPMEIRTFIVSFDHISDKQQL 1340
G ++ +++ GP DP ++ G E+ T+IV D + D +L
Sbjct: 1205 HDGQVVNKGEMIVEGPADPHDILRLKGVEELATYIV--DEVQDVYRL 1249
>gb|AAB41815.1| proline rich protein [Medicago sativa]
Length = 228
Score = 36.6 bits (83), Expect = 3.2
Identities = 21/54 (38%), Positives = 27/54 (50%)
Frame = -1
Query: 1275 AQRRASKDPQGHPEPPSRPPQNLAPSISNASSPWLRVLGLPISLSR*PCQSSSP 1114
AQ+ S P P PP+ PP N P+ AS P ++ P+ S P QSS P
Sbjct: 22 AQQAPSTSPNSSPAPPT-PPANTPPTTPQASPPPVQSSPPPVQSSPPPVQSSPP 74
>ref|NP_954610.1| taste receptor, type 2, member 135 [Mus musculus]
gb|AAP40336.1| putative taste receptor T2R35 [Mus musculus]
Length = 321
Score = 35.8 bits (81), Expect = 5.4
Identities = 21/49 (42%), Positives = 24/49 (48%)
Frame = -2
Query: 458 YFFSISIIYWYGPNYKFSFQKVLLLVNAW*SDKSMNLSAGALHPIWAHA 312
YFFSI II W P FS LLLV+ K L+ L +WA A
Sbjct: 202 YFFSIKIIMWTIPTVVFSIFMSLLLVSLVRHMKKTFLALSELRDVWAQA 250
>gb|AAR29905.1| putative response regulator receiver RIM15p [Cochliobolus
heterostrophus]
Length = 1943
Score = 35.8 bits (81), Expect = 5.4
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 13/138 (9%)
Frame = -1
Query: 1278 PAQRRASKD-----------PQGHPEPPSRPPQNLAPSISNASSPWL-RVLGLPISLSR* 1135
P +A+KD PQ P PP + P +PS S +SP L L +S +R
Sbjct: 1288 PVLEKANKDVIQKLRAEAMLPQNKPTPPLQSPNVTSPSPSLENSPMLPGSLKRTLSTNRA 1347
Query: 1134 PCQSSSPGTLS*GRYSLKTKDPCPPRPHIDEQTEGEHFHLQAPEG*ALQHYQASCKLNPS 955
P + SSP G +S ++ P P + + + G+H + K + S
Sbjct: 1348 PGRPSSPSVS--GPHSSPSRGSQPSSPLLVQFSTGQHHDRR--------------KTSSS 1391
Query: 954 QRILQH-VNSPSCLHPAL 904
L H ++PS L P +
Sbjct: 1392 SSTLSHSTSNPSTLQPGV 1409
>tpg|DAA01236.1| TPA: TPA_exp: candidate taste receptor mt2r38 [Mus musculus]
sp|Q7TQA9|T2R35_MOUSE Putative taste receptor type 2 member 35 (T2R35) (mT2r38)
Length = 312
Score = 35.8 bits (81), Expect = 5.4
Identities = 21/49 (42%), Positives = 24/49 (48%)
Frame = -2
Query: 458 YFFSISIIYWYGPNYKFSFQKVLLLVNAW*SDKSMNLSAGALHPIWAHA 312
YFFSI II W P FS LLLV+ K L+ L +WA A
Sbjct: 193 YFFSIKIIMWTIPTVVFSIFMSLLLVSLVRHMKKTFLALSELRDVWAQA 241
>ref|ZP_00461715.1| extracellular solute-binding protein, family 3 [Burkholderia
cenocepacia HI2424]
ref|ZP_00458448.1| extracellular solute-binding protein, family 3 [Burkholderia
cenocepacia AU 1054]
gb|EAM19136.1| extracellular solute-binding protein, family 3 [Burkholderia
cenocepacia HI2424]
gb|EAM08874.1| extracellular solute-binding protein, family 3 [Burkholderia
cenocepacia AU 1054]
Length = 349
Score = 35.8 bits (81), Expect = 5.4
Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
Frame = -1
Query: 1281 APAQRRASKDPQGHPEPPSRPPQNLAPSISNASSPWLRV-----LGLPISLSR*P 1132
A +RRAS+ P +P PP+ PP +AP++ +A +P ++ LG PI +R P
Sbjct: 85 ASTRRRASRHPT-NPTPPASPPMPIAPAVVSAFTPTGKLRASINLGNPILANRDP 138
>ref|ZP_00569278.1| Amidohydrolase 2 [Frankia sp. EAN1pec]
gb|EAN16518.1| Amidohydrolase 2 [Frankia sp. EAN1pec]
Length = 433
Score = 35.8 bits (81), Expect = 5.4
Identities = 25/80 (31%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Frame = +3
Query: 831 PQGEGARWRRTFGQEIYSPLLLAFTEQD-------GGNWANSHVAKFSAMDSTYSLPDNV 989
P G+G W +F + P+L A ++D GG W +A + +D + +P +
Sbjct: 184 PHGQG--WP-SFLSGYWDPMLKAIVDEDMVLCLHIGGAWDIVQLAPEAPVDHSIVIPSQL 240
Query: 990 AMLTLQELEDGSVLLRFAHL 1049
MLT Q+L G L RF L
Sbjct: 241 TMLTAQDLLFGPTLRRFPKL 260
>gb|AAA26977.1| antigen I
Length = 395
Score = 35.4 bits (80), Expect = 7.0
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 134 KLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASG-AYIFRPNGTVPISTDGQVSLTV 310
KL Y D + ++A + K+ +DGN S+P A Y PN V + TDG+ +
Sbjct: 62 KLQAYQDEQAAIKAALAELEKHK-NEDGNLSEPSAQSLVYDLEPNAQVSLVTDGK----L 116
Query: 311 LRGPILDE 334
L+ LDE
Sbjct: 117 LKASALDE 124
>ref|XP_537305.2| PREDICTED: similar to Rho-associated protein kinase 1
(Rho-associated, coiled-coil containing protein kinase 1)
(p160 ROCK-1) (p160ROCK) [Canis familiaris]
Length = 2025
Score = 35.4 bits (80), Expect = 7.0
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 11/58 (18%)
Frame = -1
Query: 1320 CDQS*R*MCGSPLAPAQRRASKDP-----------QGHPEPPSRPPQNLAPSISNASS 1180
CD R CGSPL PA+ S DP G PE P+ PP+ P+ + S
Sbjct: 610 CDFGRRSGCGSPLPPARGLGSGDPLSEGEEGEPGAPGDPEVPASPPRGREPTAGGSCS 667
>ref|XP_628930.1| hypothetical protein DDB0219906 [Dictyostelium discoideum]
gb|EAL60519.1| hypothetical protein DDB0219906 [Dictyostelium discoideum]
Length = 326
Score = 35.4 bits (80), Expect = 7.0
Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +2
Query: 113 LQYNEA-GKLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASGAYIFRP 262
+++N++ G + + + + Q+Y YYI G+ Q SGAYIFRP
Sbjct: 260 IRFNKSDGSIISIKNKTSSLVLEISQEYMYYISSTGDIESRQKSGAYIFRP 310
>emb|CAA40973.1| antigen I /II [Streptococcus sobrinus]
sp|P21979|SPAA_STRDO Cell surface antigen I/II precursor
pir||A60338 surface antigen A - Streptococcus sobrinus (strain 6715, serotype
g)
Length = 1528
Score = 35.4 bits (80), Expect = 7.0
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = +2
Query: 134 KLSLYSDSKTMVQANFEQKYKYYIGQDGNGSDPQASG-AYIFRPNGTVPISTDGQVSLTV 310
KL Y D + ++A + K+ +DGN S+P A Y PN V + TDG+ +
Sbjct: 484 KLQAYQDEQAAIKAALAELEKHK-NEDGNLSEPSAQSLVYDLEPNAQVALVTDGK----L 538
Query: 311 LRGPILDE 334
L+ LDE
Sbjct: 539 LKASALDE 546
>gb|EAQ84058.1| hypothetical protein CHGG_10462 [Chaetomium globosum CBS 148.51]
Length = 939
Score = 35.0 bits (79), Expect = 9.2
Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Frame = -1
Query: 1290 SPLAPAQRRASKDPQGHPEPPSRPPQNLAPSISNASSPWLRVLGLPISLSR*PCQSSSPG 1111
+PL +QRR+ G +PP+ PP++++P++ ++ + + S S P +S G
Sbjct: 2 NPLRSSQRRSPGAEPG--QPPAVPPRSISPAVGVGTNRPVAPRSMGSSRSMQPTSASGSG 59
Query: 1110 TLS*G-----RYSLKTKDPCPPRPHIDE 1042
+ + G R+S ++ PP P + +
Sbjct: 60 SRNDGTRRANRHSHNGREGTPPTPEVSD 87
Database: nr
Posted date: Apr 6, 2006 2:41 PM
Number of letters in database: 1,185,965,366
Number of sequences in database: 3,454,138
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,660,548,681
Number of Sequences: 3454138
Number of extensions: 83421162
Number of successful extensions: 260751
Number of sequences better than 10.0: 178
Number of HSP's better than 10.0 without gapping: 228924
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 258998
length of database: 1,185,965,366
effective HSP length: 135
effective length of database: 719,656,736
effective search space used: 292180634816
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)